6A6P

Crystal Structure of Peroxisome Proliferator-Activated Receptor Delta (PPARd)LBD in Complex with DN003316

Summary for 6A6P

DescriptorPeroxisome proliferator-activated receptor delta, {2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl}methyl)sulfanyl]phenoxy}acetic acid, HEPTYL-BETA-D-GLUCOPYRANOSIDE, ... (5 entities in total)
Functional Keywordsppardelta, complex, nuclear receptor, peroxisome proliferator-activated receptor family, ligand binding domain (lbd), structural protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight64414.88
Authors
Chin, J.W.,Cho, S.J.,Song, J.Y.,Ha, J.H. (deposition date: 2018-06-29, release date: 2019-07-10)
Primary citation
Chin, J.W.,Cho, S.J.,Song, J.Y.,Ha, J.H.
Crystal Structure of Peroxisome Proliferator-Activated Receptor Delta (PPARd)LBD in Complex with DN003316
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22811 0.2% 0.4% 5.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution