6K5L
| The crystal structure of isocitrate dehydrogenase kinase/phosphatase wtih two Mn2+ from E. coli | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ... | Authors: | Zhang, X, Lei, Z, Zheng, J, Jia, Z. | Deposit date: | 2019-05-29 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Characterization of metal binding of bifunctional kinase/phosphatase AceK and implication in activity modulation. Sci Rep, 9, 2019
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7CBQ
| Crystal structure of PDE4D catalytic domain in complex with Apremilast | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide, ... | Authors: | Zhang, X.L, Xu, Y.C. | Deposit date: | 2020-06-13 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment. Eur.J.Med.Chem., 211, 2021
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3RYT
| The Plexin A1 intracellular region in complex with Rac1 | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-A1, ... | Authors: | Zhang, X, He, H. | Deposit date: | 2011-05-11 | Release date: | 2012-01-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.582 Å) | Cite: | Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization. Sci.Signal., 5, 2012
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3SD6
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1J04
| Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro | Descriptor: | (AMINOOXY)ACETIC ACID, GLYCEROL, alanine--glyoxylate aminotransferase | Authors: | Zhang, X, Djordjevic, S, Bartlam, M, Ye, S, Rao, Z, Danpure, C.J. | Deposit date: | 2002-10-30 | Release date: | 2003-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting. Acta Crystallogr.,Sect.F, 66, 2010
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4O9L
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7CTH
| Cryo-EM structure of dengue virus serotype 2 in complex with the scFv fragment of the broadly neutralizing antibody EDE1 C10 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Core protein, Single Chain Variable Fragment | Authors: | Zhang, X, Sharma, A, Duquerroy, S, Zhou, Z.H, Rey, F.A. | Deposit date: | 2020-08-19 | Release date: | 2021-12-01 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses. Cell, 184, 2021
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8X2I
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8X2H
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4N6F
| Crystal structure of Amycolatopsis orientalis BexX complexed with G6P | Descriptor: | CALCIUM ION, FRUCTOSE -6-PHOSPHATE, Putative thiosugar synthase | Authors: | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | Deposit date: | 2013-10-11 | Release date: | 2014-05-14 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis. Nature, 509, 2014
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7DVG
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4N6E
| Crystal structure of Amycolatopsis orientalis BexX/CysO complex | Descriptor: | Putative thiosugar synthase, SULFATE ION, ThiS/MoaD family protein | Authors: | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | Deposit date: | 2013-10-11 | Release date: | 2014-05-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis. Nature, 509, 2014
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7FFF
| Structure of Venezuelan equine encephalitis virus with the receptor LDLRAD3 | Descriptor: | CALCIUM ION, Capsid protein, Low-density lipoprotein receptor class A domain-containing protein 3, ... | Authors: | Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. | Deposit date: | 2021-07-23 | Release date: | 2021-10-20 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3. Nature, 598, 2021
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4O9F
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4OA7
| Crystal structure of Tankyrase1 in complex with IWR1 | Descriptor: | 4-[(3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, Tankyrase-1, ZINC ION | Authors: | Zhang, X, He, H. | Deposit date: | 2014-01-03 | Release date: | 2015-01-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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7DV8
| The crystal structure of rice immune receptor RGA5-HMA2. | Descriptor: | Disease resistance protein RGA5 | Authors: | Zhang, X, Liu, J.F. | Deposit date: | 2021-01-12 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.447 Å) | Cite: | A designer rice NLR immune receptor confers resistance to the rice blast fungus carrying noncorresponding avirulence effectors. Proc.Natl.Acad.Sci.USA, 118, 2021
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4Q2M
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6J6A
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4Q2L
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4PR3
| Crystal structure of Brucella melitensis 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | Descriptor: | 5'-methylthioadenosine nucleosidase / s-adenosylhomocysteine nucleosidase, ADENINE, GLYCEROL, ... | Authors: | Zhang, X.C, Kang, X.S, Zhao, Y, Jiang, D.H, Li, X.M, Chen, Z.L. | Deposit date: | 2014-03-05 | Release date: | 2014-04-30 | Method: | X-RAY DIFFRACTION (2.606 Å) | Cite: | Crystal structure and biochemical studies of Brucella melitensis 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Biochem.Biophys.Res.Commun., 446, 2014
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2Q12
| Crystal Structure of BAR domain of APPL1 | Descriptor: | DCC-interacting protein 13 alpha | Authors: | Zhang, X.C, Zhu, G. | Deposit date: | 2007-05-23 | Release date: | 2007-08-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. Embo J., 26, 2007
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7FFO
| Cryo-EM structure of VEEV VLP at the 5-fold axes | Descriptor: | Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2, ... | Authors: | Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. | Deposit date: | 2021-07-23 | Release date: | 2021-10-20 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3. Nature, 598, 2021
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7FFQ
| Cryo-EM structure of VEEV VLP at the 2-fold axes | Descriptor: | Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2, ... | Authors: | Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. | Deposit date: | 2021-07-23 | Release date: | 2021-10-20 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3. Nature, 598, 2021
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7FFE
| Cryo-EM structure of VEEV VLP | Descriptor: | Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2, ... | Authors: | Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. | Deposit date: | 2021-07-23 | Release date: | 2021-10-20 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3. Nature, 598, 2021
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7FFL
| Cryo-EM structure of VEEV VLP-LDLRAD3-D1 complex at the 2-fold axes | Descriptor: | CALCIUM ION, Capsid protein, Low-density lipoprotein receptor class A domain-containing protein 3, ... | Authors: | Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. | Deposit date: | 2021-07-23 | Release date: | 2021-10-20 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3. Nature, 598, 2021
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