1J04
Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro
Summary for 1J04
Entry DOI | 10.2210/pdb1j04/pdb |
Related | 1H0C |
Descriptor | alanine--glyoxylate aminotransferase, (AMINOOXY)ACETIC ACID, GLYCEROL, ... (4 entities in total) |
Functional Keywords | transferase, aminotransferase, pyridoxal phosphate |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 44126.82 |
Authors | Zhang, X.,Djordjevic, S.,Bartlam, M.,Ye, S.,Rao, Z.,Danpure, C.J. (deposition date: 2002-10-30, release date: 2003-11-11, Last modification date: 2023-11-15) |
Primary citation | Djordjevic, S.,Zhang, X.,Bartlam, M.,Ye, S.,Rao, Z.,Danpure, C.J. Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting. Acta Crystallogr.,Sect.F, 66:233-236, 2010 Cited by PubMed: 20208150DOI: 10.1107/S1744309109054645 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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