8JJ8
| Cryo-EM structure of the beta2AR-mBRIL/1b3 Fab/Glue complex with a partial agonist | Descriptor: | Beta-2 adrenergic receptor,Soluble cytochrome b562, ~{N}-[5-[(1~{R})-2-[[(2~{R})-1-(4-methoxyphenyl)propan-2-yl]amino]-1-oxidanyl-ethyl]-2-oxidanyl-phenyl]methanamide | Authors: | He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. | Deposit date: | 2023-05-29 | Release date: | 2023-09-06 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
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2WC0
| crystal structure of human insulin degrading enzyme in complex with iodinated insulin | Descriptor: | 1,4-DIETHYLENE DIOXIDE, INSULIN A CHAIN, INSULIN B CHAIN, ... | Authors: | Manolopoulou, M, Guo, Q, Malito, E, Schilling, A.B, Tang, W.J. | Deposit date: | 2009-03-06 | Release date: | 2009-03-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular Basis of Catalytic Chamber-Assisted Unfolding and Cleavage of Human Insulin by Human Insulin Degrading Enzyme. J.Biol.Chem., 284, 2009
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8X5X
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8X5Y
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8X64
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8X63
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6XS8
| Crystal structure of Chaetomium thermophilum Vps29 complexed with RaPID-derived cyclic peptide RT-D3 | Descriptor: | 48V-DTY-GLY-TYR-ASP-PRO-LEU-GLY-LEU-LYS-TYR-PHE-ALA, Vacuolar protein sorting-associated protein 29 | Authors: | Chen, K.-E, Guo, Q, Collins, B.M. | Deposit date: | 2020-07-15 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95009851 Å) | Cite: | De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. Sci Adv, 7, 2021
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6XS7
| Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-D2 | Descriptor: | 48V-DTY-THR-THR-ILE-TYR-TRP-THR-PRO-LEU-GLY-THR-PHE-PRO-ARG-ILE-ARG, FORMIC ACID, GLYCEROL, ... | Authors: | Chen, K.-E, Guo, Q, Collins, B.M. | Deposit date: | 2020-07-15 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. Sci Adv, 7, 2021
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6XSA
| Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-L2 | Descriptor: | 48V-TYR-LEU-PRO-THR-ILE-THR-GLY-VAL-GLY-HIS-LEU-TRP-HIS-PRO-LEU, SULFATE ION, Vacuolar protein sorting-associated protein 29 | Authors: | Chen, K.-E, Guo, Q, Collins, B.M. | Deposit date: | 2020-07-15 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. Sci Adv, 7, 2021
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6XS5
| Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-D1 | Descriptor: | 48V-DTY-ILE-ILE-ASP-THR-PRO-LEU-GLY-VAL-PHE-LEU-SER-SER-LEU-LYS-ARG, FORMIC ACID, GLYCEROL, ... | Authors: | Chen, K.-E, Guo, Q, Collins, B.M. | Deposit date: | 2020-07-15 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. Sci Adv, 7, 2021
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2WBY
| Crystal structure of human insulin-degrading enzyme in complex with insulin | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN, INSULIN-DEGRADING ENZYME, ... | Authors: | Manolopoulou, M, Guo, Q, Malito, E, Schilling, A.B, Tang, W.J. | Deposit date: | 2009-03-06 | Release date: | 2009-03-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular Basis of Catalytic Chamber-Assisted Unfolding and Cleavage of Human Insulin by Human Insulin Degrading Enzyme. J.Biol.Chem., 284, 2009
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3N57
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3J3V
| Atomic model of the immature 50S subunit from Bacillus subtilis (state I-a) | Descriptor: | 50S ribosomal protein L1, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | Authors: | Li, N, Guo, Q, Zhang, Y, Yuan, Y, Ma, C, Lei, J, Gao, N. | Deposit date: | 2013-04-28 | Release date: | 2013-06-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (13.3 Å) | Cite: | Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit Nucleic Acids Res., 41, 2013
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3J3W
| Atomic model of the immature 50S subunit from Bacillus subtilis (state II-a) | Descriptor: | 50S ribosomal protein L1, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | Authors: | Li, N, Guo, Q, Zhang, Y, Yuan, Y, Ma, C, Lei, J, Gao, N. | Deposit date: | 2013-04-28 | Release date: | 2013-06-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (10.7 Å) | Cite: | Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit Nucleic Acids Res., 41, 2013
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3BM4
| Crystal Structure of Human ADP-ribose Pyrophosphatase NUDT5 In complex with magnesium and AMPcpr | Descriptor: | ADP-sugar pyrophosphatase, ALPHA-BETA METHYLENE ADP-RIBOSE, MAGNESIUM ION | Authors: | Zha, M, Guo, Q, Zhang, Y, Zhong, C, Ou, Y, Ding, J. | Deposit date: | 2007-12-12 | Release date: | 2008-05-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular Mechanism of ADP-Ribose Hydrolysis By Human NUDT5 From Structural and Kinetic Studies J.Mol.Biol., 379, 2008
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8J30
| Crystal structure of ApNGT with Q469A and M218A mutations in complex with UDP-GLC | Descriptor: | UDP-glucose:protein N-beta-glucosyltransferase, URIDINE-5'-DIPHOSPHATE, URIDINE-5'-DIPHOSPHATE-GLUCOSE | Authors: | Feng, Y, Hao, Z, Guo, Q, Zheng, J, Da, L, Peng, W. | Deposit date: | 2023-04-15 | Release date: | 2023-08-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Investigation of the Catalytic Mechanism of a Soluble N-glycosyltransferase Allows Synthesis of N-glycans at Noncanonical Sequons. Jacs Au, 3, 2023
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3H44
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3N56
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4KR1
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5XXB
| Large subunit of Toxoplasma gondii ribosome | Descriptor: | 25S RNA, 5.8S RNA, 5S RNA, ... | Authors: | Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | Deposit date: | 2017-07-03 | Release date: | 2017-08-30 | Last modified: | 2017-10-18 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii Cell Res., 27, 2017
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5XY3
| Large subunit of Trichomonas vaginalis ribosome | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | Deposit date: | 2017-07-06 | Release date: | 2017-08-30 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii Cell Res., 27, 2017
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5XYI
| Small subunit of Trichomonas vaginalis ribosome | Descriptor: | 18S, 40S ribosomal protein S13, putative, ... | Authors: | Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | Deposit date: | 2017-07-08 | Release date: | 2017-08-30 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii Cell Res., 27, 2017
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5XXU
| Small subunit of Toxoplasma gondii ribosome | Descriptor: | 18S RNA, Ribosomal protein eL41, Ribosomal protein eS1, ... | Authors: | LI, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | Deposit date: | 2017-07-05 | Release date: | 2017-08-30 | Last modified: | 2018-10-24 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii Cell Res., 27, 2017
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6L8H
| Crystal structure of CYP97C1 | Descriptor: | Carotene epsilon-monooxygenase, chloroplastic, GLYCEROL, ... | Authors: | Niu, G, Guo, Q, Liu, L. | Deposit date: | 2019-11-06 | Release date: | 2020-06-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for plant lutein biosynthesis from alpha-carotene. Proc.Natl.Acad.Sci.USA, 117, 2020
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6J94
| Crystal structure of CYP97A3 | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Protein LUTEIN DEFICIENT 5, chloroplastic | Authors: | Niu, G, Guo, Q, Wang, J, Zhao, S. | Deposit date: | 2019-01-22 | Release date: | 2020-01-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Structural basis for plant lutein biosynthesis from alpha-carotene. Proc.Natl.Acad.Sci.USA, 117, 2020
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