3L2B
 
 | | Crystal structure of the CBS and DRTGG domains of the regulatory region of Clostridium perfringens pyrophosphatase complexed with activator, diadenosine tetraphosphate | | 分子名称: | BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Probable manganase-dependent inorganic pyrophosphatase | | 著者 | Tuominen, H, Salminen, A, Oksanen, E, Jamsen, J, Heikkila, O, Lehtio, L, Magretova, N.N, Goldman, A, Baykov, A.A, Lahti, R. | | 登録日 | 2009-12-15 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Crystal Structures of the CBS and DRTGG Domains of the Regulatory Region of Clostridiumperfringens Pyrophosphatase Complexed with the Inhibitor, AMP, and Activator, Diadenosine Tetraphosphate.
J.Mol.Biol., 2010
|
|
3L31
 | | Crystal structure of the CBS and DRTGG domains of the regulatory region of Clostridium perfringens pyrophosphatase complexed with the inhibitor, AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, Probable manganase-dependent inorganic pyrophosphatase | | 著者 | Tuominen, H, Salminen, A, Oksanen, E, Jamsen, J, Heikkila, O, Lehtio, L, Magretova, N.N, Goldman, A, Baykov, A.A, Lahti, R. | | 登録日 | 2009-12-16 | | 公開日 | 2010-04-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of the CBS and DRTGG Domains of the Regulatory Region of Clostridiumperfringens Pyrophosphatase Complexed with the Inhibitor, AMP, and Activator, Diadenosine Tetraphosphate.
J.Mol.Biol., 2010
|
|
6QP4
 | | Structure of 299-452 fragment of the UspA1 protein from Moraxella catarrhalis | | 分子名称: | CHLORIDE ION, HEXANE-1,6-DIOL, UspA1, ... | | 著者 | Mikula, K.M, Kolodziejczyk, R, Goldman, A. | | 登録日 | 2019-02-13 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the UspA1 protein fragment from Moraxella catarrhalis responsible for C3d binding.
J.Struct.Biol., 208, 2019
|
|
3KXV
 | | Structure of complement Factor H variant Q1139A | | 分子名称: | Complement factor H, SULFATE ION | | 著者 | Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S. | | 登録日 | 2009-12-04 | | 公開日 | 2010-05-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | | 主引用文献 | Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d
Mol.Immunol., 47, 2010
|
|
5ML9
 | | Cocrystal structure of Fc gamma receptor IIIa interacting with Affimer F4, a specific binding protein which blocks IgG binding to the receptor. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Affimer F4 with specificity for Fc gamma receptor IIIa, CHLORIDE ION, ... | | 著者 | Robinson, J.I, Tomlinson, D.C, Baxter, E.W, Owen, R.L, Thomsen, M, Win, S.J, Nettleship, J.E, Tiede, C, Foster, R.J, Waterhouse, M.P, Harris, S.A, Owens, R.J, Fishwick, C.W.G, Goldman, A, McPherson, M.J, Morgan, A.W. | | 登録日 | 2016-12-06 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Affimer proteins inhibit immune complex binding to Fc gamma RIIIa with high specificity through competitive and allosteric modes of action.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
5MN2
 | | Cocrystal structure of Fc gamma receptor IIIa interacting with Affimer G3, a specific binding protein which blocks IgG binding to the receptor. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Affimer G3, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Robinson, J.I, Owen, R.L, Tomlinson, D.C, Baxter, E.W, Nettleship, J.E, Waterhouse, M.P, Harris, S.A, Owens, R.J, McPherson, M.J, Morgan, A.W, Tiede, C, Goldman, A, Thomsen, M. | | 登録日 | 2016-12-12 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Affimer proteins inhibit immune complex binding to Fc gamma RIIIa with high specificity through competitive and allosteric modes of action.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
1FAJ
 | |
5LZQ
 | | Crystal structure of Thermotoga maritima sodium pumping membrane integral pyrophosphatase in complex with imidodiphosphate and magnesium, and with bound sodium ion | | 分子名称: | IMIDODIPHOSPHORIC ACID, K(+)-stimulated pyrophosphate-energized sodium pump, MAGNESIUM ION, ... | | 著者 | Wilkinson, C, Kellosalo, J, Kajander, T, Goldman, A. | | 登録日 | 2016-10-01 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.495 Å) | | 主引用文献 | Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism.
Nat Commun, 7, 2016
|
|
3KZJ
 | | Structure of complement Factor H variant R1203A | | 分子名称: | Complement factor H, SULFATE ION | | 著者 | Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S. | | 登録日 | 2009-12-08 | | 公開日 | 2010-05-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d
Mol.Immunol., 47, 2010
|
|
5LZR
 | | Crystal structure of Thermotoga maritima sodium pumping membrane integral pyrophosphatase in complex with tungstate and magnesium | | 分子名称: | K(+)-stimulated pyrophosphate-energized sodium pump, MAGNESIUM ION, TUNGSTATE(VI)ION | | 著者 | Wilkinson, C, Kellosalo, J, Kajander, T, Goldman, A. | | 登録日 | 2016-10-01 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism.
Nat Commun, 7, 2016
|
|
2M4F
 | | Solution Structure of Outer surface protein E | | 分子名称: | Outer surface protein E | | 著者 | Bhattacharjee, A, Oeemig, J.S, Kolodziejczyk, R, Meri, T, Kajander, T, Iwai, H, Jokiranta, T, Goldman, A. | | 登録日 | 2013-02-05 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for Complement Evasion by Lyme Disease Pathogen Borrelia burgdorferi
J.Biol.Chem., 288, 2013
|
|
4MUC
 | | The 4th and 5th C-terminal domains of Factor H related protein 1 | | 分子名称: | Complement factor H-related protein 1, SULFATE ION | | 著者 | Bhattacharjee, A, Goldman, A, Kolodziejczyk, R, Jokiranta, T.S. | | 登録日 | 2013-09-21 | | 公開日 | 2015-02-18 | | 最終更新日 | 2015-05-06 | | 実験手法 | X-RAY DIFFRACTION (2.897 Å) | | 主引用文献 | The Major Autoantibody Epitope on Factor H in Atypical Hemolytic Uremic Syndrome Is Structurally Different from Its Homologous Site in Factor H-related Protein 1, Supporting a Novel Model for Induction of Autoimmunity in This Disease.
J.Biol.Chem., 290, 2015
|
|
2PK0
 | | Structure of the S. agalactiae serine/threonine phosphatase at 2.65 resolution | | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Rantanen, M.K, Lehtio, L, Rajagopal, L, Rubens, C.E, Goldman, A. | | 登録日 | 2007-04-17 | | 公開日 | 2007-06-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structure of Streptococcus agalactiae serine/threonine phosphatase. The subdomain conformation is coupled to the binding of a third metal ion
Febs J., 274, 2007
|
|
5LNL
 | | Crystal structure of Hsf 1608-1749 putative domain 1 | | 分子名称: | Hsf | | 著者 | Thomsen, M, Wright, J, Ridley, J, Goldman, A. | | 登録日 | 2016-08-05 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | The crystal structure of PD1, a Haemophilus surface fibril domain.
Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
2EIP
 | |
117E
 | | THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS | | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, PROTEIN (INORGANIC PYROPHOSPHATASE) | | 著者 | Tuominen, V, Heikinheimo, P, Kajander, T, Torkkel, T, Hyytia, T, Kapyla, J, Lahti, R, Cooperman, B.S, Goldman, A. | | 登録日 | 1998-09-15 | | 公開日 | 1998-12-23 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications.
J.Mol.Biol., 284, 1998
|
|
1QHM
 | | ESCHERICHIA COLI PYRUVATE FORMATE LYASE LARGE DOMAIN | | 分子名称: | PYRUVATE FORMATE-LYASE | | 著者 | Leppanen, V.-M, Merckel, M.C, Ollis, D.L, Wong, K.K, Kozarich, J.W, Goldman, A. | | 登録日 | 1999-05-19 | | 公開日 | 2000-05-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Pyruvate formate lyase is structurally homologous to type I ribonucleotide reductase.
Structure Fold.Des., 7, 1999
|
|
1E9G
 | | STRUCTURE OF INORGANIC PYROPHOSPHATASE | | 分子名称: | INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, PHOSPHATE ION | | 著者 | Heikinheimo, P, Tuominen, V, Ahonen, A.-K, Teplyakov, A, Cooperman, B.S, Baykov, A.A, Lahti, R, Goldman, A. | | 登録日 | 2000-10-12 | | 公開日 | 2001-03-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Toward a Quantum-Mechanical Description of Metal-Assisted Phosphoryl Transfer in Pyrophosphatase
Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
1E6A
 | | Fluoride-inhibited substrate complex of Saccharomyces cerevisiae inorganic pyrophosphatase | | 分子名称: | FLUORIDE ION, INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, ... | | 著者 | Heikinheimo, P, Tuominen, V, Ahonen, A.-K, Teplyakov, A, Cooperman, B.S, Baykov, A.A, Lahti, R, Goldman, A. | | 登録日 | 2000-08-09 | | 公開日 | 2001-03-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase.
Proc. Natl. Acad. Sci. U.S.A., 98, 2001
|
|
1F9C
 | | CRYSTAL STRUCTURE OF MLE D178N VARIANT | | 分子名称: | MANGANESE (II) ION, PROTEIN (MUCONATE CYCLOISOMERASE I) | | 著者 | Kajander, T, Lehtio, L, Kahn, P.C, Goldman, A. | | 登録日 | 2000-07-10 | | 公開日 | 2001-03-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Buried charged surface in proteins.
Structure Fold.Des., 8, 2000
|
|
1Q8D
 | | The crystal structure of GDNF family co-receptor alpha 1 domain 3 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GDNF family receptor alpha 1 | | 著者 | Leppanen, V.M, Bespalov, M.M, Runeberg-Roos, P, Puurand, U, Merits, A, Saarma, M, Goldman, A. | | 登録日 | 2003-08-21 | | 公開日 | 2004-08-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation.
Embo J., 23, 2004
|
|
1NU5
 | |
1P9H
 | |
1QEZ
 | | SULFOLOBUS ACIDOCALDARIUS INORGANIC PYROPHOSPHATASE: AN ARCHAEL PYROPHOSPHATASE. | | 分子名称: | MAGNESIUM ION, PROTEIN (INORGANIC PYROPHOSPHATASE) | | 著者 | Leppanen, V.-M, Nummelin, H, Hansen, T, Lahti, R, Schafer, G, Goldman, A. | | 登録日 | 1999-04-06 | | 公開日 | 1999-04-14 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Sulfolobus acidocaldarius inorganic pyrophosphatase: structure, thermostability, and effect of metal ion in an archael pyrophosphatase.
Protein Sci., 8, 1999
|
|
2AWU
 | | Synapse associated protein 97 PDZ2 domain variant C378G | | 分子名称: | AHH, Synapse-associated protein 97 | | 著者 | Von Ossowski, I, Oksanen, E, Von Ossowski, L, Cai, C, Sundberg, M, Goldman, A, Keinanen, K. | | 登録日 | 2005-09-02 | | 公開日 | 2006-08-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide
Febs J., 273, 2006
|
|
