1Q8D

The crystal structure of GDNF family co-receptor alpha 1 domain 3

Summary for 1Q8D

• Entry DOI: 10.2210/pdb1q8d/pdb
• Descriptor: GDNF family receptor alpha 1, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
• Functional Keywords: all-alpha, cys-rich, hormone-growth factor receptor complex, hormone/growth factor receptor
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Cell membrane; Lipid-anchor, GPI-anchor: Q62997
• Total number of polymer chains: 1
• Total formula weight: 12193.56

Authors

Leppanen, V.M.,Bespalov, M.M.,Runeberg-Roos, P.,Puurand, U.,Merits, A.,Saarma, M.,Goldman, A. (deposition date: 2003-08-21, release date: 2004-08-31, Last modification date: 2011-07-13)

• Primary citation: Leppanen, V.M.,Bespalov, M.M.,Runeberg-Roos, P.,Puurand, U.,Merits, A.,Saarma, M.,Goldman, A.; The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation.; Embo J., 23:1452-1462, 2004; PubMed: 15044950; DOI: 10.1038/sj.emboj.7600174

Experimental method

X-RAY DIFFRACTION (1.8 Å)