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PDB: 164 件
6WUR
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BU of 6wur by Molmil
Crystal structure of PRL-2 phosphatase C101D mutant in complex with the Bateman domain of CNNM3 magnesium transporter
分子名称: Metal transporter CNNM3, Protein tyrosine phosphatase type IVA 2, SODIUM ION
著者Kozlov, G, Gehring, K.
登録日2020-05-05
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.882 Å)
主引用文献Crystal structure of PRL phosphatase C104D mutant in complex with the Bateman domain of CNNM magnesium transporter
J.Biol.Chem., 2020
6N7E
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BU of 6n7e by Molmil
Crystal structure of the cytosolic domain of human CNNM2 in complex with AMP-PNP and Mg2+
分子名称: MAGNESIUM ION, Metal transporter CNNM2,Metal transporter CNNM2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Chen, Y.S, Gehring, K.
登録日2018-11-27
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Mg2+-ATP Sensing in CNNM, a Putative Magnesium Transporter.
Structure, 28, 2020
6DJX
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BU of 6djx by Molmil
Crystal Structure of pParkin-pUb-UbcH7 complex
分子名称: RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ...
著者Sauve, V, Sung, G, Trempe, J.F, Gehring, K.
登録日2018-05-27
公開日2018-07-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.801 Å)
主引用文献Mechanism of parkin activation by phosphorylation.
Nat. Struct. Mol. Biol., 25, 2018
4K95
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BU of 4k95 by Molmil
Crystal Structure of Parkin
分子名称: E3 ubiquitin-protein ligase parkin, ZINC ION
著者Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K.
登録日2013-04-19
公開日2013-05-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (6.499 Å)
主引用文献Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013
2QHO
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BU of 2qho by Molmil
Crystal structure of the UBA domain from EDD ubiquitin ligase in complex with ubiquitin
分子名称: E3 ubiquitin-protein ligase EDD1, Ubiquitin
著者Kozlov, G, Gehring, K.
登録日2007-07-02
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis of ubiquitin recognition by the ubiquitin-associated (UBA) domain of the ubiquitin ligase EDD.
J.Biol.Chem., 282, 2007
3KUR
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BU of 3kur by Molmil
Crystal structure of the MLLE domain of poly(A)-binding protein
分子名称: CHLORIDE ION, Polyadenylate-binding protein 1
著者Kozlov, G, Gehring, K.
登録日2009-11-27
公開日2010-02-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Determinants of PAM2 Recognition by the MLLE Domain of Poly(A)-Binding Protein.
J.Mol.Biol., 397, 2010
7SOR
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BU of 7sor by Molmil
LaM domain of human LARP1 in complex with AAA RNA
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Isoform 2 of La-related protein 1, ...
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOS
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BU of 7sos by Molmil
LaM domain of human LARP1 in complex with AAAA RNA
分子名称: Isoform 2 of La-related protein 1, POTASSIUM ION, RNA (5'-R(*AP*AP*AP*A)-3')
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7US1
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BU of 7us1 by Molmil
Structure of parkin (R0RB) bound to two phospho-ubiquitin molecules
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin, ...
著者Fakih, R, Sauve, V, Gehring, K.
登録日2022-04-22
公開日2022-06-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.484 Å)
主引用文献Structure of the second phosphoubiquitin-binding site in parkin.
J.Biol.Chem., 298, 2022
6MN6
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BU of 6mn6 by Molmil
Crystal structure of the cytosolic domain of human CNNM3
分子名称: Metal transporter CNNM3
著者Chen, Y.S, Yang, M, Gehring, K.
登録日2018-10-01
公開日2019-10-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Mg2+-ATP Sensing in CNNM, a Putative Magnesium Transporter.
Structure, 28, 2020
3EC3
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BU of 3ec3 by Molmil
Crystal structure of the bb fragment of ERp72
分子名称: Protein disulfide-isomerase A4
著者Kozlov, G, Gehring, K.
登録日2008-08-28
公開日2009-04-14
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structure of the Noncatalytic Domains and Global Fold of the Protein Disulfide Isomerase ERp72.
Structure, 17, 2009
5KES
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BU of 5kes by Molmil
Solution structure of the yeast Ddi1 HDD domain
分子名称: DNA damage-inducible protein 1
著者Trempe, J.-F, Ratcliffe, C, Veverka, V, Saskova, K, Gehring, K.
登録日2016-06-10
公開日2016-10-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.
Sci Rep, 6, 2016
4F02
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BU of 4f02 by Molmil
Crystal structure of the PABP-binding site of eIF4G in complex with RRM1-2 of PABP and poly(A)
分子名称: Eukaryotic translation initiation factor 4 gamma 1, Polyadenylate-binding protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
著者Safaee, N, Kozlov, G, Gehring, K.B.
登録日2012-05-03
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
6DJ3
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BU of 6dj3 by Molmil
Crystal structure of CNNM2 cyclic nucleotide-binding homology domain
分子名称: 1,2-ETHANEDIOL, Metal transporter CNNM2
著者Chen, Y.S, Gehring, K.
登録日2018-05-24
公開日2018-10-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg2+efflux activity.
J. Biol. Chem., 293, 2018
6DJW
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BU of 6djw by Molmil
Crystal Structure of pParkin (REP and RING2 deleted)-pUb-UbcH7 complex
分子名称: RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ...
著者Sauve, V, Sung, G, Trempe, J.F, Gehring, K.
登録日2018-05-26
公開日2018-07-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.801 Å)
主引用文献Mechanism of parkin activation by phosphorylation.
Nat. Struct. Mol. Biol., 25, 2018
6DFD
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BU of 6dfd by Molmil
Crystal structure of CNNM3 cyclic nucleotide-binding homology domain
分子名称: Metal transporter CNNM3
著者Kozlov, G, Gehring, K.
登録日2018-05-14
公開日2018-10-31
最終更新日2019-01-16
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg2+efflux activity.
J. Biol. Chem., 293, 2018
4K7D
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BU of 4k7d by Molmil
Crystal Structure of Parkin C-terminal RING domains
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, MALONATE ION, ...
著者Sauve, V, Trempe, J.-F, Menade, M, Gehring, K.
登録日2013-04-17
公開日2013-05-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013
7M1T
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BU of 7m1t by Molmil
Crystal structure of an archaeal CNNM, MtCorB, with C-terminal deletion in complex with Mg2+-ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Hemolysin, contains CBS domains, ...
著者Chen, Y.S, Kozlov, G, Gehring, K.
登録日2021-03-15
公開日2021-06-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献Crystal structure of an archaeal CorB magnesium transporter.
Nat Commun, 12, 2021
5K34
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BU of 5k34 by Molmil
Structure of the ankyrin domain of AnkB from Legionella Pneumophila
分子名称: Ankyrin-repeat protein B, GLYCEROL, SULFATE ION
著者Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2016-05-19
公開日2017-01-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System.
Structure, 25, 2017
5KDG
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BU of 5kdg by Molmil
Crystal Structure of Salmonella Typhimurium Effector GtgE
分子名称: GLYCEROL, Gifsy-2 prophage protein, SULFATE ION
著者Kozlov, G, Xu, C, Wong, K, Gehring, K, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2016-06-08
公開日2016-11-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal Structure of the Salmonella Typhimurium Effector GtgE.
PLoS ONE, 11, 2016
7SOT
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BU of 7sot by Molmil
LaM domain of human LARP1 in complex with AAAAAA oligonucleotide
分子名称: Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), SULFATE ION
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOV
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BU of 7sov by Molmil
LaM domain of human LARP1 in complex with AAAAAAAAAAA RNA polynucleotide
分子名称: GLYCEROL, Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOQ
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BU of 7soq by Molmil
LaM domain of human LARP1 in complex with AAA RNA
分子名称: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*A)-3')
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOO
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BU of 7soo by Molmil
LaM domain of human LARP1
分子名称: Isoform 2 of La-related protein 1, SODIUM ION, SULFATE ION
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOP
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BU of 7sop by Molmil
LaM domain of human LARP1 in complex with AAAUAA RNA
分子名称: Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*UP*AP*A)-3')
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022

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