6L9V
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![BU of 6l9v by Molmil](/molmil-images/mine/6l9v) | Crystal structure of mouse TIFA (T9D/C36S mutant) | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | Authors: | Nakamura, T, Yamagata, Y. | Deposit date: | 2019-11-11 | Release date: | 2020-04-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity. Sci Rep, 10, 2020
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6L9U
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![BU of 6l9u by Molmil](/molmil-images/mine/6l9u) | Crystal structure of mouse TIFA | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | Authors: | Nakamura, T, Yamagata, Y. | Deposit date: | 2019-11-11 | Release date: | 2020-04-01 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity. Sci Rep, 10, 2020
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2Z3Q
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![BU of 2z3q by Molmil](/molmil-images/mine/2z3q) | Crystal structure of the IL-15/IL-15Ra complex | Descriptor: | Interleukin-15, Interleukin-15 receptor alpha chain | Authors: | Chirifu, M, Yamagata, Y, Davis, S.J, Ikemizu, S. | Deposit date: | 2007-06-05 | Release date: | 2007-09-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans Nat.Immunol., 8, 2007
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6ILI
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![BU of 6ili by Molmil](/molmil-images/mine/6ili) | Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 6.5 | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | Authors: | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2018-10-18 | Release date: | 2018-11-07 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity J. Biol. Chem., 292, 2017
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3APX
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![BU of 3apx by Molmil](/molmil-images/mine/3apx) | Crystal structure of the A variant of human alpha1-acid glycoprotein and chlorpromazine complex | Descriptor: | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, ACETIC ACID, Alpha-1-acid glycoprotein 2 | Authors: | Nishi, K, Ono, T, Nakamura, T, Fukunaga, N, Izumi, M, Watanabe, H, Suenaga, A, Maruyama, T, Yamagata, Y, Curry, S, Otagiri, M. | Deposit date: | 2010-10-21 | Release date: | 2011-02-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms. J. Biol. Chem., 286, 2011
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3APW
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![BU of 3apw by Molmil](/molmil-images/mine/3apw) | Crystal structure of the A variant of human alpha1-acid glycoprotein and disopyramide complex | Descriptor: | Alpha-1-acid glycoprotein 2, Disopyramide | Authors: | Nishi, K, Ono, T, Nakamura, T, Fukunaga, N, Izumi, M, Watanabe, H, Suenaga, A, Maruyama, T, Yamagata, Y, Curry, S, Otagiri, M. | Deposit date: | 2010-10-21 | Release date: | 2011-02-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms. J. Biol. Chem., 286, 2011
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3APV
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![BU of 3apv by Molmil](/molmil-images/mine/3apv) | Crystal structure of the A variant of human alpha1-acid glycoprotein and amitriptyline complex | Descriptor: | ACETIC ACID, Alpha-1-acid glycoprotein 2, Amitriptyline | Authors: | Nishi, K, Ono, T, Nakamura, T, Fukunaga, N, Izumi, M, Watanabe, H, Suenaga, A, Maruyama, T, Yamagata, Y, Curry, S, Otagiri, M. | Deposit date: | 2010-10-21 | Release date: | 2011-02-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms. J. Biol. Chem., 286, 2011
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2Z3R
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![BU of 2z3r by Molmil](/molmil-images/mine/2z3r) | Crystal structure of the IL-15/IL-15Ra complex | Descriptor: | GLYCEROL, Interleukin-15, Interleukin-15 receptor alpha chain | Authors: | Chirifu, M, Yamagata, Y, Davis, S.J, Ikemizu, S. | Deposit date: | 2007-06-05 | Release date: | 2007-09-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans Nat.Immunol., 8, 2007
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3APU
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![BU of 3apu by Molmil](/molmil-images/mine/3apu) | Crystal structure of the A variant of human alpha1-acid glycoprotein | Descriptor: | Alpha-1-acid glycoprotein 2, TETRAETHYLENE GLYCOL | Authors: | Nishi, K, Ono, T, Nakamura, T, Fukunaga, N, Izumi, M, Watanabe, H, Suenaga, A, Maruyama, T, Yamagata, Y, Curry, S, Otagiri, M. | Deposit date: | 2010-10-21 | Release date: | 2011-02-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms. J. Biol. Chem., 286, 2011
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6IJY
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![BU of 6ijy by Molmil](/molmil-images/mine/6ijy) | |
7EF9
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![BU of 7ef9 by Molmil](/molmil-images/mine/7ef9) | Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form II) | Descriptor: | Adenine DNA glycosylase, DNA (5'-D(*AP*TP*GP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*CP*CP*CP*(3DR)P*GP*TP*CP*TP*C)-3'), ... | Authors: | Nakamura, T, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2021-03-21 | Release date: | 2021-06-23 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. Nucleic Acids Res., 49, 2021
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7EF8
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![BU of 7ef8 by Molmil](/molmil-images/mine/7ef8) | Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form I) | Descriptor: | Adenine DNA glycosylase, DNA (5'-D(*TP*AP*GP*TP*CP*CP*CP*(3DR)P*GP*TP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*CP*T)-3'), ... | Authors: | Nakamura, T, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2021-03-21 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. Nucleic Acids Res., 49, 2021
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7EFA
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![BU of 7efa by Molmil](/molmil-images/mine/7efa) | |
8I1C
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![BU of 8i1c by Molmil](/molmil-images/mine/8i1c) | |
8I1A
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![BU of 8i1a by Molmil](/molmil-images/mine/8i1a) | |
8I1I
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![BU of 8i1i by Molmil](/molmil-images/mine/8i1i) | Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP at pH 7.7 | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | Authors: | Nakamura, T, Yamagata, Y. | Deposit date: | 2023-01-13 | Release date: | 2023-03-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition. Febs Lett., 597, 2023
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8I1D
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![BU of 8i1d by Molmil](/molmil-images/mine/8i1d) | Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 7.7 | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | Authors: | Nakamura, T, Yamagata, Y. | Deposit date: | 2023-01-13 | Release date: | 2023-03-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition. Febs Lett., 597, 2023
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8I1E
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![BU of 8i1e by Molmil](/molmil-images/mine/8i1e) | Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 8.0 | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | Authors: | Nakamura, T, Yamagata, Y. | Deposit date: | 2023-01-13 | Release date: | 2023-03-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition. Febs Lett., 597, 2023
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8I19
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![BU of 8i19 by Molmil](/molmil-images/mine/8i19) | |
8I18
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![BU of 8i18 by Molmil](/molmil-images/mine/8i18) | |
8I1H
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![BU of 8i1h by Molmil](/molmil-images/mine/8i1h) | |
8I1J
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![BU of 8i1j by Molmil](/molmil-images/mine/8i1j) | Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP at pH 9.7 | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | Authors: | Nakamura, T, Yamagata, Y. | Deposit date: | 2023-01-13 | Release date: | 2023-03-22 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition. Febs Lett., 597, 2023
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8I8T
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![BU of 8i8t by Molmil](/molmil-images/mine/8i8t) | |
8I1F
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![BU of 8i1f by Molmil](/molmil-images/mine/8i1f) | Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 8.6 | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | Authors: | Nakamura, T, Yamagata, Y. | Deposit date: | 2023-01-13 | Release date: | 2023-03-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition. Febs Lett., 597, 2023
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8I8S
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![BU of 8i8s by Molmil](/molmil-images/mine/8i8s) | |