8GWN
| A mechanism for SARS-CoV-2 RNA capping and its inhibitor of AT-527 | Descriptor: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | Authors: | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | Deposit date: | 2022-09-17 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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4NQ0
| Structural insights into yeast histone chaperone Hif1: a scaffold protein recruiting protein complexes to core histones | Descriptor: | HAT1-interacting factor 1 | Authors: | Liu, H, Zhang, M, He, W, Zhu, Z, Teng, M, Gao, Y, Niu, L. | Deposit date: | 2013-11-23 | Release date: | 2014-07-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into yeast histone chaperone Hif1: a scaffold protein recruiting protein complexes to core histones Biochem.J., 462, 2014
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8GWK
| SARS-CoV-2 RNA E-RTC complex with RMP-nsp9 and GMPPNP | Descriptor: | Helicase, MAGNESIUM ION, Non-structural protein 7, ... | Authors: | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | Deposit date: | 2022-09-17 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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4OQT
| LINGO-1/Li81 Fab complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Li81 Fab, ... | Authors: | Pepinsky, R.B, Arndt, J.W, Quan, C, Gao, Y, Quintero-Monzon, O, Lee, X, Mi, S. | Deposit date: | 2014-02-10 | Release date: | 2014-05-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Structure of the LINGO-1-Anti-LINGO-1 Li81 Antibody Complex Provides Insights into the Biology of LINGO-1 and the Mechanism of Action of the Antibody Therapy. J.Pharmacol.Exp.Ther., 350, 2014
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5EJO
| Crystal structure of the winged helix domain in Chromatin assembly factor 1 subunit p90 | Descriptor: | Chromatin assembly factor 1 subunit p90 | Authors: | Zhang, K, Gao, Y, Li, J, Burgess, R, Han, J, Liang, H, Zhang, Z, Liu, Y. | Deposit date: | 2015-11-02 | Release date: | 2016-03-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks Nucleic Acids Res., 44, 2016
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7BTK
| E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSA01 | Descriptor: | 4-[[2-[(E)-2-[4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethenyl]-3,3-dimethyl-2H-indol-1-yl]methyl]benzoic acid, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | Authors: | Chen, X, Hu, Y.L, Liu, Q.M, Gao, Y, Yuan, R, Guo, Y. | Deposit date: | 2020-04-01 | Release date: | 2021-03-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Two-Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence. Angew.Chem.Int.Ed.Engl., 60, 2021
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7BRS
| E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSA02 | Descriptor: | 8-[2-[(E)-2-[4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethenyl]-3,3-dimethyl-indol-1-ium-1-yl]octanoic acid, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | Authors: | Chen, X, Hu, Y.L, Gao, Y, Yuan, R, Guo, Y. | Deposit date: | 2020-03-30 | Release date: | 2021-03-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Two-Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence. Angew.Chem.Int.Ed.Engl., 60, 2021
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2P1C
| T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-210 | Descriptor: | ACETATE ION, BETA-MERCAPTOETHANOL, Farnesyl pyrophosphate synthase, ... | Authors: | Cao, R, Gao, Y, Oldfield, E. | Deposit date: | 2007-03-04 | Release date: | 2008-03-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases. Proteins, 73, 2008
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7CXN
| Architecture of a SARS-CoV-2 mini replication and transcription complex | Descriptor: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | Authors: | Yan, L, Zhang, Y, Ge, J, Zheng, L, Gao, Y, Wang, T, Jia, Z, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | Deposit date: | 2020-09-02 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Architecture of a SARS-CoV-2 mini replication and transcription complex. Nat Commun, 11, 2020
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8VNM
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8VNO
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8VNS
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8V7D
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8V7F
| Human DNA polymerase eta-DNA-araC-ended primer-dAMPNPP ternary complex with Mn2+ | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T*())-3'), DNA (5'-D(*CP*AP*TP*GP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | Authors: | Chang, C, Gao, Y. | Deposit date: | 2023-12-04 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human DNA polymerase eta-DNA-araC-ended primer-dAMPNPP ternary complex with Mn2+ To Be Published
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8V7B
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8V7H
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8V7E
| Human DNA polymerase eta-DNA-araC-ended primer-dAMPNPP ternary complex with Mg2+ | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*C)-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ... | Authors: | Chang, C, Gao, Y. | Deposit date: | 2023-12-04 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Human DNA polymerase eta-DNA-araC-ended primer-dAMPNPP ternary complex with Mg2+ To Be Published
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8V7A
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8V7G
| Human DNA polymerase eta-DNA-gemC-ended primer-dAMPNPP ternary complex with Mg2+ | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*(U7B))-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ... | Authors: | Chang, C, Gao, Y. | Deposit date: | 2023-12-04 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Human DNA polymerase eta-DNA-araC-ended primer-dAMPNPP ternary complex with Mn2+ To Be Published
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8V7I
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8V7C
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8V7K
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8V7J
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8VMP
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8VMS
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