2P1C
T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-210
Summary for 2P1C
| Entry DOI | 10.2210/pdb2p1c/pdb |
| Related | 2EWG 2OGC 2OGD 2OGL |
| Descriptor | Farnesyl pyrophosphate synthase, MAGNESIUM ION, ACETATE ION, ... (6 entities in total) |
| Functional Keywords | protein-bisphosphonate complex, transferase |
| Biological source | Trypanosoma brucei |
| Total number of polymer chains | 2 |
| Total formula weight | 90115.17 |
| Authors | Cao, R.,Gao, Y.,Oldfield, E. (deposition date: 2007-03-04, release date: 2008-03-04, Last modification date: 2023-08-30) |
| Primary citation | Cao, R.,Chen, C.K.,Guo, R.T.,Wang, A.H.,Oldfield, E. Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases. Proteins, 73:431-439, 2008 Cited by PubMed: 18442135DOI: 10.1002/prot.22066 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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