2BBM
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![BU of 2bbm by Molmil](/molmil-images/mine/2bbm) | SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR | Descriptor: | CALCIUM ION, CALMODULIN, MYOSIN LIGHT CHAIN KINASE | Authors: | Clore, G.M, Bax, A, Ikura, M, Gronenborn, A.M. | Deposit date: | 1992-07-16 | Release date: | 1994-01-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of a calmodulin-target peptide complex by multidimensional NMR. Science, 256, 1992
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2BBN
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![BU of 2bbn by Molmil](/molmil-images/mine/2bbn) | SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR | Descriptor: | CALCIUM ION, CALMODULIN, MYOSIN LIGHT CHAIN KINASE | Authors: | Clore, G.M, Bax, A, Ikura, M, Gronenborn, A.M. | Deposit date: | 1992-07-16 | Release date: | 1994-01-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of a calmodulin-target peptide complex by multidimensional NMR. Science, 256, 1992
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2HF5
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![BU of 2hf5 by Molmil](/molmil-images/mine/2hf5) | The structure and function of a novel two-site calcium-binding fragment of calmodulin | Descriptor: | CALCIUM ION, Calmodulin | Authors: | Lakowski, T.M, Lee, G.M, Reid, R.E, McIntosh, L.P. | Deposit date: | 2006-06-23 | Release date: | 2007-05-01 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Calcium-induced folding of a fragment of calmodulin composed of EF-hands 2 and 3 Protein Sci., 16, 2007
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2AWI
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![BU of 2awi by Molmil](/molmil-images/mine/2awi) | Structure of PrgX Y153C mutant | Descriptor: | PrgX | Authors: | Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.k, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A. | Deposit date: | 2005-09-01 | Release date: | 2005-12-06 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AW6
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![BU of 2aw6 by Molmil](/molmil-images/mine/2aw6) | Structure of a bacterial peptide pheromone/receptor complex and its mechanism of gene regulation | Descriptor: | PrgX, peptide | Authors: | Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.K, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A. | Deposit date: | 2005-08-31 | Release date: | 2005-12-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AZ8
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![BU of 2az8 by Molmil](/molmil-images/mine/2az8) | HIV-1 Protease NL4-3 in complex with inhibitor, TL-3 | Descriptor: | PROTEASE RETROPEPSIN, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate | Authors: | Heaslet, H, Kutilek, V, Morris, G.M, Lin, Y.-C, Elder, J.H, Torbett, B.E, Stout, C.D. | Deposit date: | 2005-09-09 | Release date: | 2006-02-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Insights into the Mechanisms of Drug Resistance in HIV-1 Protease NL4-3 J.Mol.Biol., 356, 2006
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2KT5
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![BU of 2kt5 by Molmil](/molmil-images/mine/2kt5) | RRM domain of mRNA export adaptor REF2-I bound to HSV-1 ICP27 peptide | Descriptor: | ICP27, RNA and export factor-binding protein 2 | Authors: | Tunnicliffe, N.B, Golovanov, A.P, Wilson, S.A, Hautbergue, G.M. | Deposit date: | 2010-01-18 | Release date: | 2011-01-12 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Basis for the Recognition of Cellular mRNA Export Factor REF by Herpes Viral Proteins HSV-1 ICP27 and HVS ORF57. Plos Pathog., 7, 2011
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2AXU
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![BU of 2axu by Molmil](/molmil-images/mine/2axu) | Structure of PrgX | Descriptor: | PrgX | Authors: | Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.K, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A. | Deposit date: | 2005-09-06 | Release date: | 2005-12-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2CM6
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![BU of 2cm6 by Molmil](/molmil-images/mine/2cm6) | crystal structure of the C2B domain of rabphilin3A | Descriptor: | CALCIUM ION, PHOSPHATE ION, RABPHILIN-3A | Authors: | Schlicker, C, Montaville, P, Sheldrick, G.M, Becker, S. | Deposit date: | 2006-05-04 | Release date: | 2006-12-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The C2A-C2B Linker Defines the High Affinity Ca2+ Binding Mode of Rabphilin-3A. J.Biol.Chem., 282, 2007
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2KMD
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![BU of 2kmd by Molmil](/molmil-images/mine/2kmd) | Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to co-activator CBP | Descriptor: | Protein C-ets-1 | Authors: | Nelson, M.L, Kang, H, Lee, G.M, Blaszczak, A.G, Lau, D.K.W, McIntosh, L.P, Graves, B.J. | Deposit date: | 2009-07-27 | Release date: | 2010-05-05 | Last modified: | 2012-03-21 | Method: | SOLUTION NMR | Cite: | Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP. Proc.Natl.Acad.Sci.USA, 107, 2010
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2HT8
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![BU of 2ht8 by Molmil](/molmil-images/mine/2ht8) | N8 neuraminidase in complex with oseltamivir | Descriptor: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | Deposit date: | 2006-07-25 | Release date: | 2006-09-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature, 443, 2006
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2HTV
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![BU of 2htv by Molmil](/molmil-images/mine/2htv) | N4 neuraminidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | Deposit date: | 2006-07-26 | Release date: | 2006-09-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature, 443, 2006
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2AXV
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![BU of 2axv by Molmil](/molmil-images/mine/2axv) | Structure of PrgX Y153C mutant | Descriptor: | PrgX | Authors: | Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.K, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A. | Deposit date: | 2005-09-06 | Release date: | 2005-12-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AZB
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![BU of 2azb by Molmil](/molmil-images/mine/2azb) | HIV-1 Protease NL4-3 3X mutant in complex with inhibitor, TL-3 | Descriptor: | PROTEASE RETROPEPSIN, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate | Authors: | Heaslet, H, Kutilek, V, Morris, G.M, Lin, Y.-C, Elder, J.H, Torbett, B.E, Stout, C.D. | Deposit date: | 2005-09-09 | Release date: | 2006-02-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural Insights into the Mechanisms of Drug Resistance in HIV-1 Protease NL4-3 J.Mol.Biol., 356, 2006
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2HTQ
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![BU of 2htq by Molmil](/molmil-images/mine/2htq) | N8 neuraminidase in complex with zanamivir | Descriptor: | Neuraminidase, ZANAMIVIR | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | Deposit date: | 2006-07-26 | Release date: | 2006-09-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature, 443, 2006
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2AS9
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![BU of 2as9 by Molmil](/molmil-images/mine/2as9) | Functional and structural characterization of Spl proteases from staphylococcus aureus | Descriptor: | ZINC ION, serine protease | Authors: | Popowicz, G.M, Dubin, G, Stec-Niemczyk, J, Czarny, A, Dubin, A, Potempa, J, Holak, T.A. | Deposit date: | 2005-08-23 | Release date: | 2005-09-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Functional and Structural Characterization of Spl Proteases from Staphylococcus aureus J.Mol.Biol., 358, 2006
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2AZ9
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![BU of 2az9 by Molmil](/molmil-images/mine/2az9) | HIV-1 Protease NL4-3 1X mutant | Descriptor: | PROTEASE RETROPEPSIN, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate | Authors: | Heaslet, H, Kutilek, V, Morris, G.M, Lin, Y.-C, Elder, J.H, Torbett, B.E, Stout, C.D. | Deposit date: | 2005-09-09 | Release date: | 2006-02-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Insights into the Mechanisms of Drug Resistance in HIV-1 Protease NL4-3 J.Mol.Biol., 356, 2006
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2AIO
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![BU of 2aio by Molmil](/molmil-images/mine/2aio) | Metallo beta lactamase L1 from Stenotrophomonas maltophilia complexed with hydrolyzed moxalactam | Descriptor: | (2R)-2-((R)-CARBOXY{[CARBOXY(4-HYDROXYPHENYL)ACETYL]AMINO}METHOXYMETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBO XYLIC ACID, Metallo-beta-lactamase L1, SULFATE ION, ... | Authors: | Spencer, J, Read, J, Sessions, R.B, Howell, S, Blackburn, G.M, Gamblin, S.J. | Deposit date: | 2005-07-30 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Antibiotic Recognition by Binuclear Metallo-beta-Lactamases Revealed by X-ray Crystallography J.Am.Chem.Soc., 127, 2005
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2GRM
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![BU of 2grm by Molmil](/molmil-images/mine/2grm) | Crystal structure of PrgX/iCF10 complex | Descriptor: | PrgX, peptide | Authors: | Shi, K, Kozlowicz, B.K, Gu, Z.Y, Ohlendorf, D.H, Earhart, C.A, Dunny, G.M. | Deposit date: | 2006-04-24 | Release date: | 2007-04-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular basis for control of conjugation by bacterial pheromone and inhibitor peptides. Mol.Microbiol., 62, 2006
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2EU2
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![BU of 2eu2 by Molmil](/molmil-images/mine/2eu2) | Human Carbonic Anhydrase II in complex with novel inhibitors | Descriptor: | (R)-1-AMINO-1-[5-(DIMETHYLAMINO)-1,3,4-THIADIAZOL-2-YL]METHANESULFONAMIDE, Carbonic anhydrase 2, ZINC ION | Authors: | Fisher, S.Z, Govindasamy, L, Boyle, N, Agbandje-McKenna, M, Silverman, D.N, Blackburn, G.M, McKenna, R. | Deposit date: | 2005-10-28 | Release date: | 2006-07-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes. Acta Crystallogr.,Sect.F, 62, 2006
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2CG6
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![BU of 2cg6 by Molmil](/molmil-images/mine/2cg6) | Second and third fibronectin type I module pair (crystal form I). | Descriptor: | HUMAN FIBRONECTIN, SULFATE ION | Authors: | Rudino-Pinera, E, Ravelli, R.B.G, Sheldrick, G.M, Nanao, M.H, Werner, J.M, Schwarz-Linek, U, Potts, J.R, Garman, E.F. | Deposit date: | 2006-02-27 | Release date: | 2007-02-27 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The Solution and Crystal Structures of a Module Pair from the Staphylococcus Aureus-Binding Site of Human Fibronectin-A Tale with a Twist. J.Mol.Biol., 368, 2007
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2EVA
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![BU of 2eva by Molmil](/molmil-images/mine/2eva) | Structural Basis for the Interaction of TAK1 Kinase with its Activating Protein TAB1 | Descriptor: | ADENOSINE, TAK1 kinase - TAB1 chimera fusion protein | Authors: | Brown, K, Vial, S.C, Dedi, N, Long, J.M, Dunster, N.J, Cheetham, G.M. | Deposit date: | 2005-10-31 | Release date: | 2006-05-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the interaction of TAK1 kinase with its activating protein TAB1 J.Mol.Biol., 354, 2005
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2EZN
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![BU of 2ezn by Molmil](/molmil-images/mine/2ezn) | |
2DSP
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![BU of 2dsp by Molmil](/molmil-images/mine/2dsp) | Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins | Descriptor: | Insulin-like growth factor IB, Insulin-like growth factor-binding protein 4 | Authors: | Sitar, T, Popowicz, G.M, Siwanowicz, I, Huber, R, Holak, T.A. | Deposit date: | 2006-07-05 | Release date: | 2006-08-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GMN
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![BU of 2gmn by Molmil](/molmil-images/mine/2gmn) | Crystal structure of BJP-1, a subclass B3 metallo-beta-lactamase of Bradyrhizobium japonicum | Descriptor: | Metallo-beta-lactamase, ZINC ION | Authors: | Calderone, V, Benvenuti, M, Stoczko, M, Docquier, J.D, Rossolini, G.M, Mangani, S. | Deposit date: | 2006-04-07 | Release date: | 2007-04-24 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Postgenomic scan of metallo-beta-lactamase homologues in rhizobacteria: identification and characterization of BJP-1, a subclass B3 ortholog from Bradyrhizobium japonicum. Antimicrob.Agents Chemother., 50, 2006
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