2DSP
Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins
Summary for 2DSP
| Entry DOI | 10.2210/pdb2dsp/pdb |
| Related | 1WQJ 2DSQ 2DSR |
| Descriptor | Insulin-like growth factor-binding protein 4, Insulin-like growth factor IB (3 entities in total) |
| Functional Keywords | igf, igfbp, insulin, protein binding-hormone-growth factor complex, protein binding/hormone/growth factor |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted: P22692 P05019 |
| Total number of polymer chains | 2 |
| Total formula weight | 17490.25 |
| Authors | Sitar, T.,Popowicz, G.M.,Siwanowicz, I.,Huber, R.,Holak, T.A. (deposition date: 2006-07-05, release date: 2006-08-22, Last modification date: 2023-10-25) |
| Primary citation | Sitar, T.,Popowicz, G.M.,Siwanowicz, I.,Huber, R.,Holak, T.A. Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc.Natl.Acad.Sci.Usa, 103:13028-13033, 2006 Cited by PubMed: 16924115DOI: 10.1073/pnas.0605652103 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report
