2DSP
Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Insulin-like growth factor-binding protein 4 | polymer | 92 | 9826.5 | 1 | UniProt (P22692) Pfam (PF00219) | Homo sapiens (human) | IGFBP-4, IBP-4, IGF-binding protein 4 |
| 2 | B (I) | Insulin-like growth factor IB | polymer | 70 | 7663.8 | 1 | UniProt (P05019) Pfam (PF00049) UniProt (by SIFTS) (Q9NP10) | Homo sapiens (human) | IGF-IB, Somatomedin C, Mechano growth factor, MGF |
| 3 | C, D (B, I) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 17490.3 | |
| All* | Total formula weight | 17490.3 |
