1WQJ

Structural Basis for the Regulation of Insulin-Like Growth Factors (IGFs) by IGF Binding Proteins (IGFBPs)

Summary for 1WQJ

• Entry DOI: 10.2210/pdb1wqj/pdb
• Related: 1H59
• Descriptor: Insulin-like growth factor binding protein 4, Insulin-like growth factor IB (3 entities in total)
• Functional Keywords: protein-protein complex, disulfide rich, disulfide bond ladder, protein binding-hormone-growth factor complex, protein binding/hormone/growth factor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P22692 P05019
• Total number of polymer chains: 2
• Total formula weight: 16161.87

Authors

Siwanowicz, I.,Popowicz, G.M.,Wisniewska, M.,Huber, R.,Kuenkele, K.P.,Lang, K.,Engh, R.A.,Holak, T.A. (deposition date: 2004-09-29, release date: 2005-03-01, Last modification date: 2023-10-25)

• Primary citation: Siwanowicz, I.,Popowicz, G.M.,Wisniewska, M.,Huber, R.,Kuenkele, K.P.,Lang, K.,Engh, R.A.,Holak, T.A.; Structural basis for the regulation of insulin-like growth factors by IGF binding proteins; Structure, 13:155-167, 2005; PubMed: 15642270; DOI: 10.1016/j.str.2004.11.009

Experimental method

X-RAY DIFFRACTION (1.6 Å)