2KT5

RRM domain of mRNA export adaptor REF2-I bound to HSV-1 ICP27 peptide

Summary for 2KT5

• Entry DOI: 10.2210/pdb2kt5/pdb
• Related: 2F3J
• NMR Information: BMRB: 16683
• Descriptor: RNA and export factor-binding protein 2, ICP27 (2 entities in total)
• Functional Keywords: ref icp27 hsv-1, chaperone, mrna processing, mrna splicing, mrna transport, nucleus, rna-binding, spliceosome, transport, rna binding protein - viral protein complex, rna binding protein / viral protein
• Biological source: Mus musculus (mouse); More
• Cellular location: Nucleus: Q9JJW6
• Total number of polymer chains: 2
• Total formula weight: 17865.06

Authors

Tunnicliffe, N.B.,Golovanov, A.P.,Wilson, S.A.,Hautbergue, G.M. (deposition date: 2010-01-18, release date: 2011-01-12, Last modification date: 2011-07-13)

• Primary citation: Tunnicliffe, R.B.,Hautbergue, G.M.,Kalra, P.,Jackson, B.R.,Whitehouse, A.,Wilson, S.A.,Golovanov, A.P.; Structural Basis for the Recognition of Cellular mRNA Export Factor REF by Herpes Viral Proteins HSV-1 ICP27 and HVS ORF57.; Plos Pathog., 7:e1001244-e1001244, 2011; PubMed: 21253573; DOI: 10.1371/journal.ppat.1001244

Experimental method

SOLUTION NMR