RRM domain of mRNA export adaptor REF2-I bound to HSV-1 ICP27 peptide

Summary for 2KT5

DescriptorRNA and export factor-binding protein 2, ICP27 (2 entities in total)
Functional Keywordsref icp27 hsv-1, chaperone, mrna processing, mrna splicing, mrna transport, nucleus, rna-binding, spliceosome, transport, rna binding protein - viral protein complex, rna binding protein / viral protein
Biological sourceMus musculus (mouse)
Cellular locationNucleus Q9JJW6
Total number of polymer chains2
Total molecular weight17865.06
Tunnicliffe, N.B.,Golovanov, A.P.,Wilson, S.A.,Hautbergue, G.M. (deposition date: 2010-01-18, release date: 2011-01-12, Last modification date: 2011-07-13)
Primary citation
Tunnicliffe, R.B.,Hautbergue, G.M.,Kalra, P.,Jackson, B.R.,Whitehouse, A.,Wilson, S.A.,Golovanov, A.P.
Structural Basis for the Recognition of Cellular mRNA Export Factor REF by Herpes Viral Proteins HSV-1 ICP27 and HVS ORF57.
Plos Pathog., 7:e1001244-e1001244, 2011
PubMed: 21253573 (PDB entries with the same primary citation)
DOI: 10.1371/journal.ppat.1001244
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers223.7%28.4%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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