3ZJD
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![BU of 3zjd by Molmil](/molmil-images/mine/3zjd) | A20 OTU domain in reduced, active state at 1.87 A resolution | Descriptor: | 1,2-ETHANEDIOL, A20P50, CHLORIDE ION | Authors: | Kulathu, Y, Garcia, F.J, Mevissen, T.E.T, Busch, M, Arnaudo, N, Carroll, K.S, Barford, D, Komander, D. | Deposit date: | 2013-01-17 | Release date: | 2013-03-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation Nat.Commun., 4, 2013
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2IZY
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![BU of 2izy by Molmil](/molmil-images/mine/2izy) | Molecular Basis of AKAP Specificity for PKA Regulatory Subunits | Descriptor: | CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT II | Authors: | Gold, M.G, Lygren, B, Dokurno, P, Hoshi, N, McConnachie, G, Tasken, K, Carlson, C.R, Scott, J.D, Barford, D. | Deposit date: | 2006-07-27 | Release date: | 2006-11-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular Basis of Akap Specificity for Pka Regululatory Subunits Mol.Cell, 24, 2006
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4ADY
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![BU of 4ady by Molmil](/molmil-images/mine/4ady) | Crystal structure of 26S proteasome subunit Rpn2 | Descriptor: | 26S PROTEASOME REGULATORY SUBUNIT RPN2 | Authors: | Kulkarni, K, He, J, Da Fonseca, P.C.A, Krutauz, D, Glickman, M.H, Barford, D, Morris, E.P. | Deposit date: | 2012-01-04 | Release date: | 2012-03-14 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Structure of the 26S Proteasome Subunit Rpn2 Reveals its Pc Repeat Domain as a Closed Toroid of Two Concentric Alpha-Helical Rings Structure, 20, 2012
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4AEZ
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![BU of 4aez by Molmil](/molmil-images/mine/4aez) | Crystal Structure of Mitotic Checkpoint Complex | Descriptor: | MITOTIC SPINDLE CHECKPOINT COMPONENT MAD2, MITOTIC SPINDLE CHECKPOINT COMPONENT MAD3, WD REPEAT-CONTAINING PROTEIN SLP1 | Authors: | Kulkarni, K.A, Chao, W.C.H, Zhang, Z, Barford, D. | Deposit date: | 2012-01-13 | Release date: | 2012-03-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the Mitotic Checkpoint Complex Nature, 484, 2012
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4BH6
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![BU of 4bh6 by Molmil](/molmil-images/mine/4bh6) | Insights into degron recognition by APC coactivators from the structure of an Acm1-Cdh1 complex | Descriptor: | APC/C ACTIVATOR PROTEIN CDH1, APC/C-CDH1 MODULATOR 1 | Authors: | He, J, Chao, W.C.H, Zhang, Z, Yang, J, Cronin, N, Barford, D. | Deposit date: | 2013-03-29 | Release date: | 2013-06-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Insights Into Degron Recognition by Apc/C Coactivators from the Structure of an Acm1-Cdh1 Complex. Mol.Cell, 50, 2013
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4BLP
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![BU of 4blp by Molmil](/molmil-images/mine/4blp) | P4 PROTEIN FROM BACTERIOPHAGE PHI13 | Descriptor: | CITRATE ANION, GLYCEROL, PACKAGING ENZYME P4 | Authors: | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | Deposit date: | 2013-05-04 | Release date: | 2013-08-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
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4A8F
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![BU of 4a8f by Molmil](/molmil-images/mine/4a8f) | Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation | Descriptor: | 5'-D(*DAP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2011-11-21 | Release date: | 2012-07-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
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4BWY
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![BU of 4bwy by Molmil](/molmil-images/mine/4bwy) | P4 PROTEIN FROM BACTERIOPHAGE PHI8 (R32) | Descriptor: | P4 | Authors: | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | Deposit date: | 2013-07-05 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
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4A8W
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![BU of 4a8w by Molmil](/molmil-images/mine/4a8w) | Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation | Descriptor: | 5'-D(*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2011-11-21 | Release date: | 2012-07-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.04 Å) | Cite: | Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
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2XPI
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![BU of 2xpi by Molmil](/molmil-images/mine/2xpi) | Crystal structure of APC/C hetero-tetramer Cut9-Hcn1 | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT CUT9, ANAPHASE-PROMOTING COMPLEX SUBUNIT HCN1 HCN1/CDC26,20S CYCLOSOME/APC COMPLEX PROTEIN HCN1, CHAPERONE-LIKE PROTEIN HCN1, ... | Authors: | Zhang, Z, Kulkarni, K.A, Barford, D. | Deposit date: | 2010-08-26 | Release date: | 2011-03-30 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Apc/C Subunit Cdc16/Cut9 is a Contiguous Tetratricopeptide Superhelix with a Homo-Dimer Interface Similar to Cdc27 Embo J., 29, 2010
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4A8K
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![BU of 4a8k by Molmil](/molmil-images/mine/4a8k) | Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation | Descriptor: | 5'-D(*AP*AP*TP*CP)-3', 5'-D(*TP*CP)-3', GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2011-11-21 | Release date: | 2012-07-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
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4A8M
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![BU of 4a8m by Molmil](/molmil-images/mine/4a8m) | Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation | Descriptor: | 5'-D(*AP*AP*TP*CP)-3', ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2011-11-21 | Release date: | 2012-07-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
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4A8Q
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![BU of 4a8q by Molmil](/molmil-images/mine/4a8q) | Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation | Descriptor: | 5'-D(*DTP*TP*CP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2011-11-21 | Release date: | 2012-07-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
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2YIN
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![BU of 2yin by Molmil](/molmil-images/mine/2yin) | STRUCTURE OF THE COMPLEX BETWEEN Dock2 AND Rac1. | Descriptor: | DEDICATOR OF CYTOKINESIS PROTEIN 2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 | Authors: | Kulkarni, K.A, Yang, J, Zhang, Z, Barford, D. | Deposit date: | 2011-05-16 | Release date: | 2011-05-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (Dock) Nucleotide Exchange Factors. J.Biol.Chem., 286, 2011
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4A8S
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![BU of 4a8s by Molmil](/molmil-images/mine/4a8s) | Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation | Descriptor: | 5'-D(*TP*TP*TP*TP*CP*GP*CP*GP*TP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2011-11-21 | Release date: | 2012-07-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
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1HI1
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![BU of 1hi1 by Molmil](/molmil-images/mine/1hi1) | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2001-01-01 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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2YI9
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![BU of 2yi9 by Molmil](/molmil-images/mine/2yi9) | Structure of the RNA polymerase VP1 from Infectious Pancreatic Necrosis Virus in complex with magnesium | Descriptor: | CHLORIDE ION, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Graham, S.C, Sarin, L.P, Bahar, M.W, Myers, R.A, Stuart, D.I, Bamford, D.H, Grimes, J.M. | Deposit date: | 2011-05-11 | Release date: | 2011-07-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The N-Terminus of the RNA Polymerase from Infectious Pancreatic Necrosis Virus is the Determinant of Genome Attachment. Plos Pathog., 7, 2011
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4BLQ
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![BU of 4blq by Molmil](/molmil-images/mine/4blq) | P4 PROTEIN FROM BACTERIOPHAGE PHI8 | Descriptor: | P4 | Authors: | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | Deposit date: | 2013-05-04 | Release date: | 2013-08-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
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5A31
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![BU of 5a31 by Molmil](/molmil-images/mine/5a31) | Structure of the human APC-Cdh1-Hsl1-UbcH10 complex. | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | Authors: | Chang, L, Zhang, Z, Yang, J, Mclaughlin, S.H, Barford, D. | Deposit date: | 2015-05-26 | Release date: | 2015-11-18 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Atomic Structure of the Apc/C and its Mechanism of Protein Ubiquitination. Nature, 522, 2015
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2B4S
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![BU of 2b4s by Molmil](/molmil-images/mine/2b4s) | Crystal structure of a complex between PTP1B and the insulin receptor tyrosine kinase | Descriptor: | Insulin receptor, SULFATE ION, Tyrosine-protein phosphatase, ... | Authors: | Li, S, Depetris, R.S, Barford, D, Chernoff, J, Hubbard, S.R. | Deposit date: | 2005-09-26 | Release date: | 2005-11-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of a Complex between Protein Tyrosine Phosphatase 1B and the Insulin Receptor Tyrosine Kinase. Structure, 13, 2005
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4A8Y
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![BU of 4a8y by Molmil](/molmil-images/mine/4a8y) | Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation | Descriptor: | 5'-D(*TP*TP*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2011-11-21 | Release date: | 2012-07-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.41 Å) | Cite: | Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
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5BPZ
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![BU of 5bpz by Molmil](/molmil-images/mine/5bpz) | Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain | Descriptor: | 1,2-ETHANEDIOL, Anapc5 protein | Authors: | Cronin, N, Yang, J, Zhang, Z, Barford, D. | Deposit date: | 2015-05-28 | Release date: | 2015-09-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain. J.Mol.Biol., 427, 2015
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5BPT
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![BU of 5bpt by Molmil](/molmil-images/mine/5bpt) | |
7FRT
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![BU of 7frt by Molmil](/molmil-images/mine/7frt) | PanDDA analysis group deposition of ground-state model of PTP1B, using pre-clustering, cluster 1 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Mehlman, T, Biel, J, Azeem, S.M, Nelson, E.R, Hossain, S, Dunnett, L.E, Paterson, N.G, Douangamath, A, Talon, R, Axford, D, Orins, H, von Delft, F, Keedy, D.A. | Deposit date: | 2022-10-26 | Release date: | 2022-11-23 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B. Elife, 12, 2023
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7FRU
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![BU of 7fru by Molmil](/molmil-images/mine/7fru) | PanDDA analysis group deposition of ground-state model of PTP1B, using pre-clustering, cluster 2 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Mehlman, T, Biel, J, Azeem, S.M, Nelson, E.R, Hossain, S, Dunnett, L.E, Paterson, N.G, Douangamath, A, Talon, R, Axford, D, Orins, H, von Delft, F, Keedy, D.A. | Deposit date: | 2022-10-26 | Release date: | 2022-11-23 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B. Elife, 12, 2023
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