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PDB: 66 件
3DFR
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CRYSTAL STRUCTURES OF ESCHERICHIA COLI AND LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE REFINED AT 1.7 ANGSTROMS RESOLUTION. I. GENERAL FEATURES AND BINDING OF METHOTREXATE
分子名称: DIHYDROFOLATE REDUCTASE, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Filman, D.J, Matthews, D.A, Bolin, J.T, Kraut, J.
登録日1982-06-25
公開日1982-10-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
J.Biol.Chem., 257, 1982
4DFR
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CRYSTAL STRUCTURES OF ESCHERICHIA COLI AND LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE REFINED AT 1.7 ANGSTROMS RESOLUTION. I. GENERAL FEATURES AND BINDING OF METHOTREXATE
分子名称: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
著者Filman, D.J, Matthews, D.A, Bolin, J.T, Kraut, J.
登録日1982-06-25
公開日1982-10-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
J.Biol.Chem., 257, 1982
2PLV
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BU of 2plv by Molmil
STRUCTURAL FACTORS THAT CONTROL CONFORMATIONAL TRANSITIONS AND SEROTYPE SPECIFICITY IN TYPE 3 POLIOVIRUS
分子名称: HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP1), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP2), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP3), ...
著者Filman, D.J, Hogle, J.M.
登録日1989-10-17
公開日1989-10-17
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus
EMBO J., 8, 1989
6NEF
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Outer Membrane Cytochrome S Filament from Geobacter Sulfurreducens
分子名称: C-type cytochrome OmcS, HEME C, MAGNESIUM ION
著者Filman, D.J, Marino, S.F, Ward, J.E, Yang, L, Mester, Z, Bullitt, E, Lovley, D.R, Strauss, M.
登録日2018-12-17
公開日2019-07-03
最終更新日2019-09-11
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire.
Commun Biol, 2, 2019
1EV1
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ECHOVIRUS 1
分子名称: ECHOVIRUS 1, MYRISTIC ACID, PALMITIC ACID
著者Wien, M.W, Filman, D.J, Hogle, J.M.
登録日1997-12-02
公開日1999-01-27
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Structure determination of echovirus 1.
Acta Crystallogr.,Sect.D, 54, 1998
4R0E
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BU of 4r0e by Molmil
Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Low-Fidelity Mutant 3Dpol H273R
分子名称: RNA-directed RNA polymerase
著者Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M.
登録日2014-07-30
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Dynamics as a Contributor to Error-prone Replication by an RNA-dependent RNA Polymerase.
J.Biol.Chem., 289, 2014
1HXS
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CRYSTAL STRUCTURE OF MAHONEY STRAIN OF POLIOVIRUS AT 2.2A RESOLUTION
分子名称: GENOME POLYPROTEIN, COAT PROTEIN VP1, COAT PROTEIN VP2, ...
著者Miller, S.T, Hogle, J.M, Filman, D.J.
登録日2001-01-16
公開日2002-01-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ab initio phasing of high-symmetry macromolecular complexes: successful phasing of authentic poliovirus data to 3.0 A resolution.
J.Mol.Biol., 307, 2001
5KWL
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expanded poliovirus in complex with VHH 10E
分子名称: VHH 10E, VP1, VP2, ...
著者Strauss, M, Schotte, L, Filman, D.J, Hogle, J.M.
登録日2016-07-18
公開日2016-11-02
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State.
J. Virol., 91, 2017
433D
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CRYSTAL STRUCTURE OF A 14 BASE PAIR RNA DUPLEX WITH NONSYMMETRICAL TANDEM G.U WOBBLE BASE PAIRS
分子名称: 5'-R(*GP*GP*UP*AP*UP*UP*GP*CP*GP*GP*UP*AP*CP*C)-3'
著者Trikha, J, Filman, D.J, Hogle, J.M.
登録日1998-10-22
公開日1998-12-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of a 14 bp RNA duplex with non-symmetrical tandem GxU wobble base pairs.
Nucleic Acids Res., 27, 1999
1PO1
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POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R80633, AN INHIBITOR OF VIRAL REPLICATION
分子名称: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
著者Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
登録日1997-01-08
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1PO2
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POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R77975, AN INHIBITOR OF VIRAL REPLICATION
分子名称: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
著者Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
登録日1997-01-08
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1PVC
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REFINEMENT OF THE SABIN STRAIN OF TYPE 3 POLIOVIRUS AT 2.4 ANGSTROMS AND THE CRYSTAL STRUCTURES OF ITS VARIANTS AT 2.9 ANGSTROMS RESOLUTION
分子名称: MYRISTIC ACID, POLIOVIRUS TYPE 3, SABIN STRAIN, ...
著者Syed, R, Filman, D.J, Hogle, J.M.
登録日1995-03-30
公開日1995-09-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Refinement of the Sabin Strain of Type 3 Poliovirus at 2.4 Angstroms and the Crystal Structures of its Variants at 2.9 Angstroms Resolution
To be Published
1POV
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ROLE AND MECHANISM OF THE MATURATION CLEAVAGE OF VP0 IN POLIOVIRUS ASSEMBLY: STRUCTURE OF THE EMPTY CAPSID ASSEMBLY INTERMEDIATE AT 2.9 ANGSTROMS RESOLUTION
分子名称: MYRISTIC ACID, POLIOVIRUS NATIVE EMPTY CAPSID (TYPE 1), SPHINGOSINE
著者Basavappa, R, Filman, D.J, Hogle, J.M.
登録日1995-08-10
公開日1995-12-07
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty capsid assembly intermediate at 2.9 A resolution.
Protein Sci., 3, 1994
1VBE
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POLIOVIRUS (TYPE 3, SABIN STRAIN, MUTANT 242-H2) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBA
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POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBB
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BU of 1vbb by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R80633
分子名称: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBC
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POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R77975
分子名称: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBD
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POLIOVIRUS (TYPE 1, MAHONEY STRAIN) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1PIV
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BINDING OF THE ANTIVIRAL DRUG WIN51711 TO THE SABIN STRAIN OF TYPE 3 POLIOVIRUS: STRUCTURAL COMPARISON WITH DRUG BINDING IN RHINOVIRUS 14
分子名称: 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, MYRISTIC ACID, POLIOVIRUS TYPE 3 (SUBUNIT VP1), ...
著者Hiremath, C.N, Grant, R.A, Filman, D.J, Hogle, J.M.
登録日1995-02-02
公開日1995-06-03
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.
Acta Crystallogr.,Sect.D, 51, 1995
1G6Q
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CRYSTAL STRUCTURE OF YEAST ARGININE METHYLTRANSFERASE, HMT1
分子名称: HNRNP ARGININE N-METHYLTRANSFERASE
著者Weiss, V.H, McBride, A.E, Soriano, M.A, Filman, D.J, Silver, P.A, Hogle, J.M.
登録日2000-11-07
公開日2000-12-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structure and oligomerization of the yeast arginine methyltransferase, Hmt1.
Nat.Struct.Biol., 7, 2000
5IWD
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HCMV DNA polymerase subunit UL44 complex with a small molecule
分子名称: 5-methylidene-3-(methylsulfanyl)-2-benzothiophen-4(5H)-one, DNA polymerase processivity factor
著者Chen, H, Coen, D.M, Hogle, J.M, Filman, D.J.
登録日2016-03-22
公開日2016-11-30
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions.
ACS Infect Dis, 3, 2017
6Q0B
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Poliovirus (Type 1 Mahoney), receptor-catalysed 135S particle incubated with anti-VP1 mAb at RT for 1 hr
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Hogle, J.M, Filman, D.J, Shah, P.N.M.
登録日2019-08-01
公開日2020-08-05
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.
Plos Pathog., 16, 2020
5IXA
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HCMV DNA polymerase processivity subunit UL44 at neutral pH and low salt
分子名称: DNA polymerase processivity factor
著者Chen, H, Coen, D.M, Hogle, J.M, Filman, D.J.
登録日2016-03-23
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.684 Å)
主引用文献A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions.
ACS Infect Dis, 3, 2017
2IJD
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Crystal Structure of the Poliovirus Precursor Protein 3CD
分子名称: Picornain 3C, RNA-directed RNA polymerase, SULFATE ION, ...
著者Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M.
登録日2006-09-29
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase.
J.Virol., 81, 2007
5KTZ
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expanded poliovirus in complex with VHH 12B
分子名称: Genome polyprotein, VHH 12B, VP1, ...
著者Strauss, M, Schotte, L, Filman, D.J, Hogle, J.M.
登録日2016-07-12
公開日2016-11-02
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State.
J. Virol., 91, 2017

 

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