6NEF
Outer Membrane Cytochrome S Filament from Geobacter Sulfurreducens
Summary for 6NEF
| Entry DOI | 10.2210/pdb6nef/pdb |
| EMDB information | 9357 |
| Descriptor | C-type cytochrome OmcS, HEME C, MAGNESIUM ION (3 entities in total) |
| Functional Keywords | conductive, filament, nanowire, six-heme multiheme c-type cytochrome, protein fibril |
| Biological source | Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) |
| Total number of polymer chains | 1 |
| Total formula weight | 46721.33 |
| Authors | Filman, D.J.,Marino, S.F.,Ward, J.E.,Yang, L.,Mester, Z.,Bullitt, E.,Lovley, D.R.,Strauss, M. (deposition date: 2018-12-17, release date: 2019-07-03, Last modification date: 2024-10-23) |
| Primary citation | Filman, D.J.,Marino, S.F.,Ward, J.E.,Yang, L.,Mester, Z.,Bullitt, E.,Lovley, D.R.,Strauss, M. Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire. Commun Biol, 2:219-219, 2019 Cited by PubMed Abstract: Electrically conductive pili from species, termed bacterial nanowires, are intensely studied for their biological significance and potential in the development of new materials. Using cryo-electron microscopy, we have characterized nanowires from conductive pili preparations that are composed solely of head-to-tail stacked monomers of the six-heme C-type cytochrome OmcS. The unique fold of OmcS - closely wrapped around a continuous stack of hemes that can serve as an uninterrupted path for electron transport - generates a scaffold that supports the unbranched chain of hemes along the central axis of the filament. We present here, at 3.4 Å resolution, the structure of this cytochrome-based filament and discuss its possible role in long-range biological electron transport. PubMed: 31240257DOI: 10.1038/s42003-019-0448-9 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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