6R76
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6R77
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3ZUK
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![BU of 3zuk by Molmil](/molmil-images/mine/3zuk) | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ZINC METALLOPROTEASE ZMP1 IN COMPLEX WITH INHIBITOR | 分子名称: | 2,2',2''-NITRILOTRIETHANOL, ACETATE ION, CALCIUM ION, ... | 著者 | Ferraris, D.M, Sbardella, D, Petrera, A, Marini, S, Amstutz, B, Coletta, M, Sander, P, Rizzi, M. | 登録日 | 2011-07-19 | 公開日 | 2011-08-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Mycobacterium Tuberculosis Zinc-Dependent Metalloprotease-1 (Zmp1), a Metalloprotease Involved in Pathogenicity. J.Biol.Chem., 286, 2011
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4TVO
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4TVM
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4LVQ
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6T3E
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![BU of 6t3e by Molmil](/molmil-images/mine/6t3e) | Structure of Thermococcus litoralis Delta(1)-pyrroline-2-carboxylate reductase in complex with NADH and L-proline | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DELTA1-pyrroline-2-carboxylate reductase, PROLINE | 著者 | Ferraris, D.M, Miggiano, R, Ferrario, E, Rizzi, M. | 登録日 | 2019-10-10 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of Thermococcus litoralis Delta1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline. Acta Crystallogr D Struct Biol, 76, 2020
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2WQW
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7Z6C
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![BU of 7z6c by Molmil](/molmil-images/mine/7z6c) | Crystal structure of human Dihydroorotate Dehydrogenase in complex with the inhibitor 2-Hydroxy-N-(2-ispropyl-5-methyl-4-phenoxyphenyl)pyrazolo[1,5-a]pyridine-3-carboxamide. | 分子名称: | ACETATE ION, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | 著者 | Alberti, M, Lolli, M.L, Boschi, D, Sainas, S, Rizzi, M, Ferraris, D.M, Miggiano, R. | 登録日 | 2022-03-11 | 公開日 | 2022-10-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a ]pyridine Scaffold: SAR of the Aryloxyaryl Moiety. J.Med.Chem., 65, 2022
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5HKF
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![BU of 5hkf by Molmil](/molmil-images/mine/5hkf) | Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with 5-phospho-alpha-D-ribosyl 1-diphosphate (PRPP) | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Orotate phosphoribosyltransferase | 著者 | Donini, S, Ferraris, D.M, Bolognesi, G, Rizzi, M. | 登録日 | 2016-01-14 | 公開日 | 2017-01-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis. Sci Rep, 7, 2017
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5HKI
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![BU of 5hki by Molmil](/molmil-images/mine/5hki) | Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with Fe(III) dicitrate | 分子名称: | Iron(III) dicitrate, Orotate phosphoribosyltransferase | 著者 | Donini, S, Ferraris, D.M, Bolognesi, G, Rizzi, M. | 登録日 | 2016-01-14 | 公開日 | 2017-01-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis. Sci Rep, 7, 2017
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7QPO
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8OFW
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5MP7
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![BU of 5mp7 by Molmil](/molmil-images/mine/5mp7) | Crystal structure of phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis | 分子名称: | ACETATE ION, Ribose-phosphate pyrophosphokinase | 著者 | Donini, S, Garavaglia, S, Ferraris, D.M, Miggiano, R, Mori, S, Shibayama, K, Rizzi, M. | 登録日 | 2016-12-16 | 公開日 | 2017-04-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis. PLoS ONE, 12, 2017
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6S6W
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![BU of 6s6w by Molmil](/molmil-images/mine/6s6w) | Crystal Structure of human ALDH1A3 in complex with 2,6-diphenylimidazo[1,2-a]pyridine (compound GA11) and NAD+ | 分子名称: | 2,6-diphenylimidazo[1,2-a]pyridine, Aldehyde dehydrogenase family 1 member A3, GLYCEROL, ... | 著者 | Gelardi, E.L.M, Quattrini, L, LaMotta, C, Ferraris, D.M, Garavaglia, S. | 登録日 | 2019-07-03 | 公開日 | 2020-04-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells. J.Med.Chem., 63, 2020
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2WQX
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![BU of 2wqx by Molmil](/molmil-images/mine/2wqx) | InlB321_4R: S199R, D200R, G206R, A227R, C242A mutant of the Listeria monocytogenes InlB internalin domain | 分子名称: | INTERNALIN B | 著者 | Niemann, H.H, Ferraris, D.M, Heinz, D.W. | 登録日 | 2009-08-27 | 公開日 | 2009-11-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Ligand-Mediated Dimerization of the met Receptor Tyrosine Kinase by the Bacterial Invasion Protein Inlb. J.Mol.Biol., 395, 2010
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2UZX
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![BU of 2uzx by Molmil](/molmil-images/mine/2uzx) | Structure of the human receptor tyrosine kinase Met in complex with the Listeria monocytogenes invasion protein InlB: Crystal form I | 分子名称: | HEPATOCYTE GROWTH FACTOR RECEPTOR, INTERNALIN B | 著者 | Niemann, H.H, Jager, V, Butler, P.J.G, Van Den Heuvel, J, Schmidt, S, Ferraris, D, Gherardi, E, Heinz, D.W. | 登録日 | 2007-05-02 | 公開日 | 2007-08-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of the Human Receptor Tyrosine Kinase met in Complex with the Listeria Invasion Protein Inlb Cell(Cambridge,Mass.), 130, 2007
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2UZY
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![BU of 2uzy by Molmil](/molmil-images/mine/2uzy) | Structure of the human receptor tyrosine kinase Met in complex with the Listeria monocytogenes invasion protein inlb: low resolution, Crystal form II | 分子名称: | HEPATOCYTE GROWTH FACTOR RECEPTOR, INTERNALIN B | 著者 | Niemann, H.H, Jager, V, Butler, P.J.G, van den Heuvel, J, Schmidt, S, Ferraris, D, Gherardi, E, Heinz, D.W. | 登録日 | 2007-05-02 | 公開日 | 2007-08-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structure of the Human Receptor Tyrosine Kinase met in Complex with the Listeria Invasion Protein Inlb Cell(Cambridge,Mass.), 130, 2007
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6G0W
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![BU of 6g0w by Molmil](/molmil-images/mine/6g0w) | Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor MCD72 | 分子名称: | 4-[3-[4-(4-fluorophenyl)piperidin-1-yl]carbonylphenoxy]benzamide, Poly [ADP-ribose] polymerase 14 | 著者 | Karlberg, T, Thorsell, A.G, Holechek, J, Lease, R, Ferraris, D, Schuler, H. | 登録日 | 2018-03-20 | 公開日 | 2018-05-23 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Design, synthesis and evaluation of potent and selective inhibitors of mono-(ADP-ribosyl)transferases PARP10 and PARP14. Bioorg. Med. Chem. Lett., 28, 2018
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2C0F
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![BU of 2c0f by Molmil](/molmil-images/mine/2c0f) | Structure of Wind Y53F mutant | 分子名称: | WINDBEUTEL PROTEIN | 著者 | Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M. | 登録日 | 2005-09-02 | 公開日 | 2006-08-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants. Acta Crystallogr.,Sect.D, 62, 2006
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2C0G
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![BU of 2c0g by Molmil](/molmil-images/mine/2c0g) | Structure of PDI-related Chaperone, Wind mutant-Y53S | 分子名称: | CHLORIDE ION, SODIUM ION, WINDBEUTEL PROTEIN | 著者 | Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M. | 登録日 | 2005-09-02 | 公開日 | 2006-08-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants. Acta Crystallogr.,Sect.D, 62, 2006
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2C0E
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![BU of 2c0e by Molmil](/molmil-images/mine/2c0e) | Structure of PDI-related Chaperone, Wind with his-tag on C-terminus. | 分子名称: | WINDBEUTEL PROTEIN | 著者 | Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M. | 登録日 | 2005-09-01 | 公開日 | 2006-08-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants. Acta Crystallogr.,Sect.D, 62, 2006
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2C1Y
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![BU of 2c1y by Molmil](/molmil-images/mine/2c1y) | Structure of PDI-related Chaperone, Wind mutant-Y55K | 分子名称: | WINDBEUTEL PROTEIN | 著者 | Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M. | 登録日 | 2005-09-22 | 公開日 | 2006-08-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants. Acta Crystallogr.,Sect.D, 62, 2006
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2QC7
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![BU of 2qc7 by Molmil](/molmil-images/mine/2qc7) | Crystal structure of the protein-disulfide isomerase related chaperone ERp29 | 分子名称: | Endoplasmic reticulum protein ERp29 | 著者 | Barak, N.N, Sevvana, M, Neumann, P, Malesevic, M, Naumann, K, Fischer, G, Sheldrick, G.M, Stubbs, M.T, Ferrari, D.M. | 登録日 | 2007-06-19 | 公開日 | 2008-06-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure and functional analysis of the protein disulfide isomerase-related protein ERp29. J.Mol.Biol., 385, 2009
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1OVN
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![BU of 1ovn by Molmil](/molmil-images/mine/1ovn) | Crystal Structure and Functional Analysis of Drosophila Wind-- a PDI-Related Protein | 分子名称: | CESIUM ION, Windbeutel | 著者 | Ma, Q, Guo, C, Barnewitz, K, Sheldrick, G.M, Soling, H.D, Uson, I, Ferrari, D.M. | 登録日 | 2003-03-27 | 公開日 | 2004-02-24 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure and functional analysis of Drosophila Wind, a protein-disulfide isomerase-related protein. J.Biol.Chem., 278, 2003
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