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PDB: 72 件

4V8Y
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Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex
分子名称: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ...
著者Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W.
登録日2013-07-20
公開日2014-07-09
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
3BSQ
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Crystal structure of human kallikrein 7 produced as a secretion protein in E.coli
分子名称: Kallikrein-7, SULFATE ION
著者Fernandez, I.S, Standker, L, Magert, H.J, Forssmann, W.G, Gimenez-Gallego, G, Romero, A.
登録日2007-12-26
公開日2008-04-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human epidermal kallikrein 7 (hK7) synthesized directly in its native state in E. coli: insights into the atomic basis of its inhibition by LEKTI domain 6 (LD6)
J.Mol.Biol., 377, 2008
3FIM
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Crystal structure of aryl-alcohol-oxidase from Pleurotus eryingii
分子名称: Aryl-alcohol oxidase, FLAVIN-ADENINE DINUCLEOTIDE
著者Fernandez, I.S.
登録日2008-12-12
公開日2009-11-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Novel structural features in the GMC family of oxidoreductases revealed by the crystal structure of fungal aryl-alcohol oxidase
Acta Crystallogr.,Sect.D, 65, 2009
4V92
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Kluyveromyces lactis 80S ribosome in complex with CrPV-IRES
分子名称: 18S RRNA, ES1, ES10, ...
著者Fernandez, I.S, Bai, X, Scheres, S.H.W, Ramakrishnan, V.
登録日2014-03-21
公開日2014-07-09
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
4V91
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Kluyveromyces lactis 80S ribosome in complex with CrPV-IRES
分子名称: 25S RRNA, 5.8S RRNA, 5S RRNA, ...
著者Fernandez, I.S, Bai, X, Scheres, S.H.W, Ramakrishnan, V.
登録日2014-03-21
公開日2014-07-09
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
4V9I
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Crystal structure of thermus thermophilus 70S in complex with tRNAs and mRNA containing a pseudouridine in a stop codon
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S Ribosomal protein S10, ...
著者Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V.
登録日2013-04-04
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
4V8Z
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Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex
分子名称: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ...
著者Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W.
登録日2013-07-20
公開日2014-07-09
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
7UFI
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VchTnsC AAA+ ATPase with DNA, single heptamer
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*TP*CP*CP*AP*GP*TP*AP*CP*AP*GP*CP*GP*CP*GP*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*AP*GP*CP*CP*GP*CP*GP*CP*TP*GP*TP*AP*CP*TP*GP*GP*AP*G)-3'), ...
著者Fernandez, I.S, Sternberg, S.H.
登録日2022-03-22
公開日2022-06-08
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Selective TnsC recruitment enhances the fidelity of RNA-guided transposition.
Nature, 609, 2022
7UFM
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VchTnsC AAA+ with DNA (double heptamer)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (36-MER), VchTnsC
著者Fernandez, I.S, Sternberg, S.H.
登録日2022-03-22
公開日2022-06-08
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Selective TnsC recruitment enhances the fidelity of RNA-guided transposition.
Nature, 609, 2022
6UZ7
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K.lactis 80S ribosome with p/PE tRNA and eIF5B
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
著者Fernandez, I.S, Huang, B.Y.
登録日2019-11-14
公開日2020-01-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation.
Proc.Natl.Acad.Sci.USA, 117, 2020
1BR0
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THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A
分子名称: PROTEIN (SYNTAXIN 1-A)
著者Fernandez, I, Ubach, J, Dubulova, I, Zhang, X, Sudhof, T.C, Rizo, J.
登録日1998-08-25
公開日1998-09-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A.
Cell(Cambridge,Mass.), 94, 1998
4JYA
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Crystal structures of pseudouridinilated stop codons with ASLs
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V.
登録日2013-03-29
公開日2013-06-26
最終更新日2013-08-21
実験手法X-RAY DIFFRACTION (3.098 Å)
主引用文献Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
4JV5
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Crystal structures of pseudouridinilated stop codons with ASLs
分子名称: 16S ribosomal RNA, 30S ribosomal protein 20, 30S ribosomal protein S10, ...
著者Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V.
登録日2013-03-25
公開日2013-06-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.162 Å)
主引用文献Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
4K0K
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Crystal structure of the Thermus thermophilus 30S ribosomal subunit complexed with a serine-ASL and mRNA containing a stop codon
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V.
登録日2013-04-04
公開日2013-06-26
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
2YMZ
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Crystal structure of chicken Galectin 2
分子名称: GALECTIN 2, SULFATE ION, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Fernandez, I.S, Ruiz, F.M, Solis, D, Gabius, H.-J, Romero, A.
登録日2012-10-11
公開日2013-08-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fine-Tuning of Prototype Chicken Galectins: Structure of Cg-2 and Structure-Activity Correlations
Acta Crystallogr.,Sect.D, 69, 2013
1KTX
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KALIOTOXIN (1-37) SHOWS STRUCTURAL DIFFERENCES WITH RELATED POTASSIUM CHANNEL BLOCKERS
分子名称: KALIOTOXIN
著者Fernandez, I, Romi, R, Szendefi, S, Martin-Eauclaire, M.-F, Rochat, H, Van Rietschtoten, J, Pons, M, Giralt, E.
登録日1994-06-02
公開日1995-01-26
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Kaliotoxin (1-37) shows structural differences with related potassium channel blockers.
Biochemistry, 33, 1994
1K5W
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THREE-DIMENSIONAL STRUCTURE OF THE SYNAPTOTAGMIN 1 C2B-DOMAIN: SYNAPTOTAGMIN 1 AS A PHOSPHOLIPID BINDING MACHINE
分子名称: CALCIUM ION, Synaptotagmin I
著者Fernandez, I, Arac, D, Ubach, J, Gerber, S.H, Shin, O, Gao, Y, Anderson, R.G.W, Sudhof, T.C, Rizo, J.
登録日2001-10-12
公開日2002-01-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.
Neuron, 32, 2001
7Q3Q
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Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing nanobody VHH-12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Fernandez, I, Pederzoli, R, Rey, F.A.
登録日2021-10-28
公開日2022-11-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献NANOBODIES AGAINST SARS-COV-2 NEUTRALIZE VARIANTS OF CONCERN AND EXPLORE CONFORMATIONAL DIFFERENCES ON THE SPIKE PROTEIN
To Be Published
7Q3R
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Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing nanobodies VHH-F04 and VHH-G09
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Spike glycoprotein, ...
著者Fernandez, I, Pederzoli, R, Rey, F.A.
登録日2021-10-28
公開日2022-11-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献NANOBODIES AGAINST SARS-COV-2 NEUTRALIZE VARIANTS OF CONCERN AND EXPLORE CONFORMATIONAL DIFFERENCES ON THE SPIKE PROTEIN
To Be Published
7QF1
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Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.6264
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV2.6264 heavy chain, CV2.6264 light chain, ...
著者Fernandez, I, Pederzoli, R, Rey, F.A.
登録日2021-12-03
公開日2022-05-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
J.Exp.Med., 219, 2022
7QF0
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Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.2325
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CV2.2325 heavy chain, ...
著者Fernandez, I, Pederzoli, R, Rey, F.A.
登録日2021-12-03
公開日2022-05-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
J.Exp.Med., 219, 2022
7QEZ
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Crystal structure of the SARS-CoV-2 RBD in complex with the ultrapotent antibody CV2.1169 and CR3022
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 heavy chain, CR3022 light chain, ...
著者Fernandez, I, Rey, F.A.
登録日2021-12-03
公開日2022-05-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
J.Exp.Med., 219, 2022
3JUT
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Acidic Fibroblast Growth Factor (FGF-1) complexed with gentisic acid
分子名称: 2,5-dihydroxybenzoic acid, Heparin-binding growth factor 1
著者Fernandez, I.S, Gimenez-Gallego, G, Romero, A.
登録日2009-09-15
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors.
J.Biol.Chem., 285, 2010
7PC2
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HIV-1 Env (BG505 SOSIP.664) in complex with the IgA bNAb 7-269 and the antibody 3BNC117.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC IgG Fab heavy chain, ...
著者Fernandez, I, Bontems, F, Pehau-Arnaudet, G, Rey, F.
登録日2021-08-03
公開日2022-02-23
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller.
J.Exp.Med., 219, 2022
8RM0
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Cryo-EM structure of a Foamy Virus fusion glycoprotein stabilized in the prefusion conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp130, ...
著者Fernandez, I, Backovic, M.
登録日2024-01-04
公開日2024-10-23
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo- and pneumoviruses.
Sci Adv, 10, 2024

 

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