1K5W

THREE-DIMENSIONAL STRUCTURE OF THE SYNAPTOTAGMIN 1 C2B-DOMAIN: SYNAPTOTAGMIN 1 AS A PHOSPHOLIPID BINDING MACHINE

Summary for 1K5W

DescriptorSynaptotagmin I, CALCIUM ION (2 entities in total)
Functional Keywordsc2b-domain, c2-domain, synaptotagmin i, calcium-binding, phospholipid-binding, synapsis, neurotransmitter release, synaptic vesicle exocytosis, endocytosis-exocytosis complex, endocytosis/exocytosis
Biological sourceRattus norvegicus (Norway rat)
Cellular locationCytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein P21707
Total number of polymer chains1
Total molecular weight17432.36
Authors
Fernandez, I.,Arac, D.,Ubach, J.,Gerber, S.H.,Shin, O.,Gao, Y.,Anderson, R.G.W.,Sudhof, T.C.,Rizo, J. (deposition date: 2001-10-12, release date: 2002-01-23, Last modification date: 2011-07-13)
Primary citation
Fernandez, I.,Arac, D.,Ubach, J.,Gerber, S.H.,Shin, O.,Gao, Y.,Anderson, R.G.,Sudhof, T.C.,Rizo, J.
Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.
Neuron, 32:1057-1069, 2001
PubMed: 11754837 (PDB entries with the same primary citation)
DOI: 10.1016/S0896-6273(01)00548-7
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

ClashscoreRamachandran outliersSidechain outliers301.0%18.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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