Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 17 results

7PLR
DownloadVisualize
BU of 7plr by Molmil
Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound Baloxavir
Descriptor: Baloxavir acid, FORMIC ACID, GLYCEROL, ...
Authors:Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K.
Deposit date:2021-09-01
Release date:2022-09-14
Last modified:2024-09-18
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Biophysical and structural study of La Crosse virus endonuclease inhibition for the development of new antiviral options.
Iucrj, 11, 2024
7OA4
DownloadVisualize
BU of 7oa4 by Molmil
Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001
Descriptor: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, FORMIC ACID, MANGANESE (II) ION, ...
Authors:Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K.
Deposit date:2021-04-19
Release date:2022-08-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Biophysical and structural study of La Crosse virus endonuclease inhibition for the development of new antiviral options.
Iucrj, 11, 2024
8PIE
DownloadVisualize
BU of 8pie by Molmil
Crystal structure of the human nucleoside diphosphate kinase B domain in complex with the product AT-8500 formed by catalysis of compound AT-9010
Descriptor: GLYCEROL, Nucleoside diphosphate kinase B, [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methyl phosphono hydrogen phosphate
Authors:Feracci, M, Chazot, A, Ferron, F, Alvarez, K, Canard, B.
Deposit date:2023-06-21
Release date:2024-07-31
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolution.
Plos Biol., 22, 2024
6RLC
DownloadVisualize
BU of 6rlc by Molmil
Crystal structure of the PDZ tandem of syntenin in complex with fragment F13
Descriptor: (2~{S})-2-[3-(4-chlorophenyl)sulfanylpropanoylamino]-3-methyl-butanoic acid, ACETATE ION, Syntenin-1
Authors:Feracci, M, Barral, K.
Deposit date:2019-05-02
Release date:2021-02-03
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loadifing with syndecan and EpCAM cargo.
J Extracell Vesicles, 10, 2020
6R9H
DownloadVisualize
BU of 6r9h by Molmil
Crystal structure of the PDZ tandem of syntenin in complex with fragment C58
Descriptor: (2~{S})-2-[2-(4-chlorophenyl)sulfanylethanoylamino]-3-methyl-butanoic acid, ACETATE ION, PHOSPHATE ION, ...
Authors:Feracci, M, Barral, K.
Deposit date:2019-04-03
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loadifing with syndecan and EpCAM cargo.
J Extracell Vesicles, 10, 2020
8PYW
DownloadVisualize
BU of 8pyw by Molmil
Crystal structure of the human Nucleoside-diphosphate kinase B domain bound to compound diphosphate form of AT-9052-Sp.
Descriptor: GLYCEROL, Nucleoside diphosphate kinase B, [[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-sulfanyl-phosphoryl] dihydrogen phosphate
Authors:Feracci, M, Chazot, A.
Deposit date:2023-07-26
Release date:2023-12-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.553 Å)
Cite:An exonuclease-resistant chain-terminating nucleotide analogue targeting the SARS-CoV-2 replicase complex.
Nucleic Acids Res., 52, 2024
8AAK
DownloadVisualize
BU of 8aak by Molmil
Crystal structure of the PDZ tandem of syntenin in complex with compound 29
Descriptor: (2~{S})-2-[[(2~{S})-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)-3-phenyl-propanoyl]amino]propanoic acid, GLYCEROL, Syntenin-1
Authors:Feracci, M, Barral, K.
Deposit date:2022-07-01
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.554 Å)
Cite:Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach.
J.Med.Chem., 66, 2023
8AAP
DownloadVisualize
BU of 8aap by Molmil
Crystal structure of the PDZ tandem of syntenin in complex with compound SYNTi
Descriptor: (2S)-2-[[(2S)-2-(6-bromanyl-3-oxidanylidene-1H-isoindol-2-yl)-3-[4-(5-ethanoyl-2-fluoranyl-phenyl)phenyl]propanoyl]amino]propanoic acid, Syntenin-1
Authors:Feracci, M, Barral, K.
Deposit date:2022-07-01
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.174 Å)
Cite:Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach.
J.Med.Chem., 66, 2023
8AAO
DownloadVisualize
BU of 8aao by Molmil
Crystal structure of the PDZ tandem of syntenin in complex with compound 95
Descriptor: (2~{S})-2-[[(2~{S})-3-[4-(5-ethanoyl-2-fluoranyl-phenyl)phenyl]-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)propanoyl]amino]propanoic acid, Syntenin-1
Authors:Feracci, M, Barral, K.
Deposit date:2022-07-01
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.469 Å)
Cite:Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach.
J.Med.Chem., 66, 2023
8AAI
DownloadVisualize
BU of 8aai by Molmil
Crystal structure of the PDZ tandem of syntenin in complex with fragment E5
Descriptor: (2~{S})-2-[[(2~{S})-3-methyl-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)butanoyl]amino]propanoic acid, Syntenin-1
Authors:Feracci, M, Barral, K.
Deposit date:2022-07-01
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach.
J.Med.Chem., 66, 2023
2LKQ
DownloadVisualize
BU of 2lkq by Molmil
NMR structure of the lambda 5 22-45 peptide
Descriptor: Immunoglobulin lambda-like polypeptide 1
Authors:Elantak, L, Espeli, M, Boned, A, Bornet, O, Breton, C, Feracci, M, Roche, P, Guerlesquin, F, Schiff, C.
Deposit date:2011-10-19
Release date:2012-10-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis for Galectin-1-dependent Pre-B Cell Receptor (Pre-BCR) Activation.
J.Biol.Chem., 287, 2012
7ED5
DownloadVisualize
BU of 7ed5 by Molmil
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase
Descriptor: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ...
Authors:Shannon, A, Fattorini, V, Sama, B, Selisko, B, Feracci, M, Falcou, C, Gauffre, P, El Kazzi, P, Delpal, A, Decroly, E, Alvarez, K, Eydoux, C, Guillemot, J.-C, Moussa, A, Good, S, Colla, P, Lin, K, Sommadossi, J.-P, Zhu, Y.X, Yan, X.D, Shi, H, Ferron, F, Canard, B.
Deposit date:2021-03-15
Release date:2022-02-16
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.
Nat Commun, 13, 2022
5ELR
DownloadVisualize
BU of 5elr by Molmil
Structure of the KH-QUA2 domain of T-STAR in complex with AAUAAU RNA
Descriptor: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
Authors:Dominguez, C, Feracci, M.
Deposit date:2015-11-05
Release date:2016-01-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016
5ELT
DownloadVisualize
BU of 5elt by Molmil
Structure of the QUA1-KH domain of T-STAR in complex with UAAU RNA
Descriptor: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
Authors:Dominguez, C, Feracci, M.
Deposit date:2015-11-05
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016
5EL3
DownloadVisualize
BU of 5el3 by Molmil
Structure of the KH domain of T-STAR
Descriptor: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
Authors:Dominguez, C, Feracci, M.
Deposit date:2015-11-04
Release date:2016-01-13
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016
5EMO
DownloadVisualize
BU of 5emo by Molmil
Structure of the star domain of T-STAR in complex with AUUAAA RNA
Descriptor: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
Authors:Dominguez, C, Feracci, M.
Deposit date:2015-11-06
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016
5ELS
DownloadVisualize
BU of 5els by Molmil
Structure of the KH domain of T-STAR in complex with AAAUAA RNA
Descriptor: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
Authors:Dominguez, C, Feracci, M.
Deposit date:2015-11-05
Release date:2016-01-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.873 Å)
Cite:Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon