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PDB: 101 件
5E6Y
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BU of 5e6y by Molmil
Crystal structure of E.Coli branching enzyme in complex with alpha cyclodextrin
分子名称: 1,4-alpha-glucan branching enzyme GlgB, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), GLYCEROL
著者Feng, L, Nosrati, M, Geiger, J.H.
登録日2015-10-11
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of Escherichia coli branching enzyme in complex with cyclodextrins.
Acta Crystallogr D Struct Biol, 72, 2016
3ORG
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BU of 3org by Molmil
Crystal Structure of a eukaryotic CLC transporter
分子名称: CHLORIDE ION, CmCLC
著者Feng, L, MacKinnon, R.
登録日2010-09-07
公開日2010-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycle.
Science, 330, 2010
6WDO
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BU of 6wdo by Molmil
Cryo-EM structure of mitochondrial calcium uniporter holocomplex in high Ca2+
分子名称: CALCIUM ION, Calcium uniporter protein, mitochondrial, ...
著者Feng, L, Zhang, J, Fan, M.
登録日2020-04-01
公開日2020-05-27
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex.
Nature, 582, 2020
4LQ1
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BU of 4lq1 by Molmil
Crystal Structure of E.Coli Branching Enzyme in complex with maltohexaose
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者Feng, L, Geiger, J.H.
登録日2013-07-17
公開日2015-04-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structures of Escherichia coli Branching Enzyme in Complex with Linear Oligosaccharides.
Biochemistry, 54, 2015
4LPC
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BU of 4lpc by Molmil
Crystal Structure of E.Coli Branching Enzyme in complex with maltoheptaose
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者Feng, L, Geiger, J.H.
登録日2013-07-16
公開日2015-04-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal Structures of Escherichia coli Branching Enzyme in Complex with Linear Oligosaccharides.
Biochemistry, 54, 2015
6NPK
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Structure of the TM domain
分子名称: Solute carrier family 12 (sodium/potassium/chloride transporter), member 2
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2019-08-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
6NPJ
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Structure of the NKCC1 CTD
分子名称: Sodium-potassium-chloride cotransporter 1
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
6NPL
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Cryo-EM structure of NKCC1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ...
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2019-08-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
6NPH
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Structure of NKCC1 TM domain
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ...
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2020-01-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
4O0J
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HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[4-(4-chlorophenyl)-6-(3,4-dimethylphenyl)-2,5-dimethylpyridin-3-yl]ethanoic acid
分子名称: (2S)-tert-butoxy[4-(4-chlorophenyl)-6-(3,4-dimethylphenyl)-2,5-dimethylpyridin-3-yl]ethanoic acid, Integrase, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2013-12-13
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase.
Plos Pathog., 10, 2014
4ID1
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HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor
分子名称: (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, Gag-Pol polyprotein, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2012-12-11
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GVM
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BU of 4gvm by Molmil
HIV-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor
分子名称: (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](tert-butoxy)ethanoic acid, ARSENIC, Gag-Pol polyprotein
著者Feng, L, Kvaratskhelia, M.
登録日2012-08-30
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors.
J.Biol.Chem., 288, 2013
4GW6
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BU of 4gw6 by Molmil
HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor
分子名称: (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](tert-butoxy)ethanoic acid, ARSENIC, Gag-Pol polyprotein
著者Feng, L, Kvaratskhelia, M.
登録日2012-08-31
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors.
J.Biol.Chem., 288, 2013
4TSX
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BU of 4tsx by Molmil
HIV-1 Integrase Catalytic Core Domain Mutant Complexed with Allosteric Inhibitor
分子名称: (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, Integrase, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2014-06-19
公開日2014-12-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The mechanism of H171T resistance reveals the importance of N -protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase.
Retrovirology, 11, 2014
4JLH
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BU of 4jlh by Molmil
HIV-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor
分子名称: (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](methoxy)ethanoic acid, HIV-1 Integrase catalytic core domain, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2013-03-12
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors.
J.Biol.Chem., 288, 2013
5JL4
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BU of 5jl4 by Molmil
Inhibitor resistant mutant catalytic core domain of HIV-1 Integrase
分子名称: Integrase, SULFATE ION
著者Feng, L, Kobe, M, Kvaratskhelia, M.
登録日2016-04-26
公開日2017-10-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.758 Å)
主引用文献Resistance to pyridine-based inhibitor KF116 reveals an unexpected role of integrase in HIV-1 Gag-Pol polyprotein proteolytic processing.
J. Biol. Chem., 292, 2017
8INJ
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BU of 8inj by Molmil
Crystal structure of UGT74AN3-UDP-DIG
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIGITOXIGENIN, Glycosyltransferase, ...
著者Feng, L, Wei, H.
登録日2023-03-10
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal structure of UGT74AN3-UDP-DIG
To Be Published
8JJQ
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BU of 8jjq by Molmil
Structure of SenB in complex with UDP-GalNAc at 1.64 Angstroms resolution
分子名称: TIGR04348 family glycosyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE
著者Feng, L, Wei, H.
登録日2023-05-31
公開日2024-02-07
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structure of SenB in complex with UDP-GalNAc at 1.64 Angstroms resolution
To Be Published
8IN7
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BU of 8in7 by Molmil
Crystal structure of UGT74AN3-UDP
分子名称: Glycosyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Feng, L, Wei, H.
登録日2023-03-08
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of UGT74AN3-UDP
To Be Published
4RZE
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BU of 4rze by Molmil
Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant
分子名称: GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者Fengwei, L, Xuyang, T, Anzhong, L, Li, L, Yuan, L, Hangzi, C, Qiao, W, Tianwei, L.
登録日2014-12-21
公開日2015-03-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
8DYP
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BU of 8dyp by Molmil
Crystal structure of human cystine transporter cystinosin
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Cystinosin, Nanobody P10, ...
著者Guo, X, Feng, L.
登録日2022-08-04
公開日2022-11-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure and mechanism of human cystine exporter cystinosin.
Cell, 185, 2022
7N98
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Cryo-EM structure of MFSD2A
分子名称: Sodium-dependent lysophosphatidylcholine symporter 1
著者Zhang, J, Feng, L.
登録日2021-06-17
公開日2021-08-04
最終更新日2021-09-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A.
Nature, 596, 2021
7SL9
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CryoEM structure of SMCT1
分子名称: Sodium-coupled monocarboxylate transporter 1, butanoic acid, nanobody Nb2
著者Qu, Q, Han, L, Panova, O, Feng, L, Skiniotis, G.
登録日2021-10-23
公開日2021-12-15
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure and mechanism of the SGLT family of glucose transporters.
Nature, 601, 2022
7SLA
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CryoEM structure of SGLT1 at 3.15 Angstrom resolution
分子名称: CHOLESTEROL HEMISUCCINATE, Sodium/glucose cotransporter 1, nanobody Nb1
著者Qu, Q, Han, L, Panova, O, Feng, L, Skiniotis, G.
登録日2021-10-23
公開日2021-12-15
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structure and mechanism of the SGLT family of glucose transporters.
Nature, 601, 2022
7SL8
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CryoEM structure of SGLT1 at 3.4 A resolution
分子名称: CHOLESTEROL, Sodium/glucose cotransporter 1, nanobody Nb1
著者Qu, Q, Han, L, Panova, O, Feng, L, Skiniotis, G.
登録日2021-10-23
公開日2021-12-15
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure and mechanism of the SGLT family of glucose transporters.
Nature, 601, 2022

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