8DYP

Crystal structure of human cystine transporter cystinosin

Summary for 8DYP

• Entry DOI: 10.2210/pdb8dyp/pdb
• Descriptor: Cystinosin, Nanobody P10, SULFATE ION, ... (4 entities in total)
• Functional Keywords: lysosomal transporter, proton-coupled transporter, cystine transporter, cystinosis, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 50741.30

Authors

Guo, X.,Feng, L. (deposition date: 2022-08-04, release date: 2022-11-16, Last modification date: 2023-10-18)

• Primary citation: Guo, X.,Schmiege, P.,Assafa, T.E.,Wang, R.,Xu, Y.,Donnelly, L.,Fine, M.,Ni, X.,Jiang, J.,Millhauser, G.,Feng, L.,Li, X.; Structure and mechanism of human cystine exporter cystinosin.; Cell, 185:3739-3752.e18, 2022; PubMed: 36113465; DOI: 10.1016/j.cell.2022.08.020

Experimental method

X-RAY DIFFRACTION (3.4 Å)