8DYP
Crystal structure of human cystine transporter cystinosin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cystinosin | polymer | 332 | 37173.4 | 1 | UniProt (O60931) Pfam (PF04193) | Homo sapiens (human) | |
| 2 | B (B) | Nanobody P10 | polymer | 118 | 13019.3 | 1 | synthetic construct | ||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 1 | Chemie (OLC) |
Sequence modifications
A: 25 - 356 (UniProt: O60931)
| PDB | External Database | Details |
|---|---|---|
| Ala 36 | Asn 36 | conflict |
| Ala 41 | Asn 41 | conflict |
| Ala 51 | Asn 51 | conflict |
| Ala 66 | Asn 66 | conflict |
| Ala 84 | Asn 84 | conflict |
| Ala 104 | Asn 104 | conflict |
| Ala 107 | Asn 107 | conflict |
| Ile 260 | Thr 260 | variant |
| Ala 301 | Asn 301 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50192.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 548.7 | |
| All* | Total formula weight | 50741.3 |
