1WAN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wan by Molmil](/molmil-images/mine/1wan) | DNA DTA TRIPLEX, NMR, 7 STRUCTURES | Descriptor: | DNA (5'-D(*AP*GP*AP*TP*AP*GP*AP*AP*CP*CP*CP*CP*TP*TP*CP*TP*AP*TP*CP*TP*TP*AP*TP*AP*TP*CP*TP*(D3)P*TP*CP*TP*T)-3') | Authors: | Wang, E, Koshlap, K.M, Gillespie, P, Dervan, P.B, Feigon, J. | Deposit date: | 1996-01-14 | Release date: | 1996-07-11 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3. J.Mol.Biol., 257, 1996
|
|
7LMA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lma by Molmil](/molmil-images/mine/7lma) | Tetrahymena telomerase T3D2 structure at 3.3 Angstrom | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. | Deposit date: | 2021-02-05 | Release date: | 2021-05-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
|
|
7LMB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lmb by Molmil](/molmil-images/mine/7lmb) | Tetrahymena telomerase T5D5 structure at 3.8 Angstrom | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. | Deposit date: | 2021-02-05 | Release date: | 2021-05-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
|
|
7TRC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7trc by Molmil](/molmil-images/mine/7trc) | Human telomerase H/ACA RNP at 3.3 Angstrom | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
|
|
5KQE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kqe by Molmil](/molmil-images/mine/5kqe) | |
4ERD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4erd by Molmil](/molmil-images/mine/4erd) | Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 in complex with stem IV of telomerase RNA | Descriptor: | 5'-R(P*GP*GP*UP*CP*GP*AP*CP*AP*UP*CP*UP*UP*CP*GP*GP*AP*UP*GP*GP*AP*CP*C)-3', POTASSIUM ION, Telomerase associated protein p65 | Authors: | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | Deposit date: | 2012-04-19 | Release date: | 2012-06-20 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.589 Å) | Cite: | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol.Cell, 47, 2012
|
|
6D6V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d6v by Molmil](/molmil-images/mine/6d6v) | CryoEM structure of Tetrahymena telomerase with telomeric DNA at 4.8 Angstrom resolution | Descriptor: | DNA (5'-D(P*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3'), RNA (159-MER), Telomerase associated protein p65, ... | Authors: | Jiang, J, Wang, Y, Susac, L, Chan, H, Basu, R, Zhou, Z.H, Feigon, J. | Deposit date: | 2018-04-22 | Release date: | 2018-05-30 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure of Telomerase with Telomeric DNA. Cell, 173, 2018
|
|
7TRD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7trd by Molmil](/molmil-images/mine/7trd) | Human telomerase catalytic core structure at 3.3 Angstrom | Descriptor: | Telomerase RNA, partial sequence, Telomerase reverse transcriptase, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
|
|
7TRE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tre by Molmil](/molmil-images/mine/7tre) | Human telomerase catalytic core with shelterin protein TPP1 | Descriptor: | Adrenocortical dysplasia protein homolog, Telomerase RNA, partial sequence, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
|
|
7TRF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7trf by Molmil](/molmil-images/mine/7trf) | Human telomerase catalytic core RNP with H2A/H2B | Descriptor: | Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
|
|
1Y2Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y2y by Molmil](/molmil-images/mine/1y2y) | Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy | Descriptor: | Ribosome biogenesis protein Nop10 | Authors: | Khanna, M, Wu, H, Johansson, C, Caizergues-Ferrer, M, Feigon, J. | Deposit date: | 2004-11-23 | Release date: | 2005-12-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA RNA, 12, 2006
|
|
5KNW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5knw by Molmil](/molmil-images/mine/5knw) | |
1TLR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tlr by Molmil](/molmil-images/mine/1tlr) | |
156D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 156d by Molmil](/molmil-images/mine/156d) | |
1K4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k4x by Molmil](/molmil-images/mine/1k4x) | POTASSIUM FORM OF OXY-1.5 QUADRUPLEX DNA | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3') | Authors: | Schultze, P, Hud, N.V, Smith, F.W, Feigon, J. | Deposit date: | 1999-06-08 | Release date: | 1999-06-23 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | The effect of sodium, potassium and ammonium ions on the conformation of the dimeric quadruplex formed by the Oxytricha nova telomere repeat oligonucleotide d(G(4)T(4)G(4)). Nucleic Acids Res., 27, 1999
|
|
1LWM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lwm by Molmil](/molmil-images/mine/1lwm) | Solution Structure of the Sequence-Non-Specific HMGB protein NHP6A | Descriptor: | NONHISTONE CHROMOSOMAL PROTEIN 6A | Authors: | Masse, J.E, Wong, B, Yen, Y.-M, Allain, F.H.-T, Johnson, R.C, Feigon, J. | Deposit date: | 2002-05-31 | Release date: | 2002-10-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding J.Mol.Biol., 323, 2002
|
|
185D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 185d by Molmil](/molmil-images/mine/185d) | |
1LWA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lwa by Molmil](/molmil-images/mine/1lwa) | Solution Structure of SRY_DNA | Descriptor: | 5'-D(*CP*TP*GP*AP*AP*CP*AP*AP*TP*CP*AP*CP*CP*CP*C)-3', 5'-D(*GP*GP*GP*GP*TP*GP*AP*TP*TP*GP*TP*TP*CP*AP*G)-3' | Authors: | Masse, J.E, Wong, B, Yen, Y.-M, Allain, F.H.-T, Johnson, R.C, Feigon, J. | Deposit date: | 2002-05-30 | Release date: | 2002-10-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding J.Mol.Biol., 323, 2002
|
|
148D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 148d by Molmil](/molmil-images/mine/148d) | |
2K96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2k96 by Molmil](/molmil-images/mine/2k96) | Solution structure of the RDC-refined P2B-P3 pseudoknot from human telomerase RNA (delta U177) | Descriptor: | TELOMERASE RNA P2B-P3 PSEUDOKNOT | Authors: | Kim, N.-K, Zhang, Q, Zhou, J, Theimer, C.A, Peterson, R.D, Feigon, J. | Deposit date: | 2008-09-29 | Release date: | 2008-11-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure and Dynamics of the Wild-type Pseudoknot of Human Telomerase RNA. J.Mol.Biol., 384, 2008
|
|
6D12
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d12 by Molmil](/molmil-images/mine/6d12) | Crystal structure of C-terminal xRRM domain of human Larp7 bound to 7SK stem-loop 4 RNA | Descriptor: | La-related protein 7, human 7SK RNA stem-loop 4 | Authors: | Eichhorn, C.D, Cascio, D, Sawaya, M.R, Feigon, J. | Deposit date: | 2018-04-11 | Release date: | 2018-06-27 | Last modified: | 2020-01-15 | Method: | X-RAY DIFFRACTION (2.205 Å) | Cite: | Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6DCC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dcc by Molmil](/molmil-images/mine/6dcc) | Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA | Descriptor: | 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | Authors: | Yang, Y, Eichhorn, C, Cascio, D, Feigon, J. | Deposit date: | 2018-05-04 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE. Nat. Chem. Biol., 15, 2019
|
|
6DCB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dcb by Molmil](/molmil-images/mine/6dcb) | Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA | Descriptor: | 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | Authors: | Yang, Y, Eichhorn, C, Cascio, D, Feigon, J. | Deposit date: | 2018-05-04 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE. Nat. Chem. Biol., 15, 2019
|
|
1K4B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k4b by Molmil](/molmil-images/mine/1k4b) | STRUCTURE OF AGUU RNA TETRALOOP, NMR, 20 STRUCTURES | Descriptor: | 5'-R(*GP*GP*UP*UP*CP*AP*GP*UP*UP*GP*AP*AP*CP*C)-3' | Authors: | Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J. | Deposit date: | 2001-10-07 | Release date: | 2001-12-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III. EMBO J., 20, 2001
|
|
1K4A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k4a by Molmil](/molmil-images/mine/1k4a) | STRUCTURE OF AGAA RNA TETRALOOP, NMR, 20 STRUCTURES | Descriptor: | 5'-R(*GP*GP*UP*UP*CP*AP*GP*AP*AP*GP*AP*AP*CP*C)-3' | Authors: | Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J. | Deposit date: | 2001-10-07 | Release date: | 2001-12-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III. EMBO J., 20, 2001
|
|