Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 128 results
5DXE
DownloadVisualize
BU of 5dxe by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-P4 and Estradiol
Descriptor: ESTRADIOL, Estrogen receptor, Nuclear receptor coactivator 2
Authors:Fanning, S.W, Speltz, T.E, Mayne, C.G, Tajkhorshid, E, Greene, G.L, Moore, T.W.
Deposit date:2015-09-23
Release date:2016-08-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Angew.Chem.Int.Ed.Engl., 55, 2016
3QXV
DownloadVisualize
BU of 3qxv by Molmil
Structure of an Anti-Methotrexate CDR1-4 Graft VHH Antibody in Complex with Methotrexate
Descriptor: Anti-Methotrexate CDR1-4 Graft VHH, METHOTREXATE, SULFATE ION
Authors:Fanning, S.W, Horn, J.R.
Deposit date:2011-03-02
Release date:2011-07-27
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop.
Protein Sci., 20, 2011
6V8T
DownloadVisualize
BU of 6v8t by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with LSZ102
Descriptor: Estrogen receptor, LSZ102
Authors:Fanning, S.W, Greene, G.L.
Deposit date:2019-12-12
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022
6VPF
DownloadVisualize
BU of 6vpf by Molmil
Estrogen Receptor Alpha Ligand Binding Domain in Complex with the Selective Estrogen Receptor Modulator Clomiphene
Descriptor: Clomifene, Estrogen receptor
Authors:Fanning, S.W, Greene, G.L.
Deposit date:2020-02-03
Release date:2020-09-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022
4POY
DownloadVisualize
BU of 4poy by Molmil
Engineered Dual Specific VHH antibody
Descriptor: VHH-metal
Authors:Fanning, S.W, Walter, R, Horn, J.R.
Deposit date:2014-02-26
Release date:2014-09-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.
Protein Eng.Des.Sel., 27, 2014
4POU
DownloadVisualize
BU of 4pou by Molmil
VHH-metal in Complex with RNase A
Descriptor: Ribonuclease pancreatic, VHH Antibody
Authors:Fanning, S.W, Walter, R, Horn, J.R.
Deposit date:2014-02-26
Release date:2014-09-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.
Protein Eng.Des.Sel., 27, 2014
4PPT
DownloadVisualize
BU of 4ppt by Molmil
Engineered Dual Specific VHH Antibody in Complex with a Nickel (II) Ion
Descriptor: Engineered single domain VHH antibody, NICKEL (II) ION, SULFATE ION
Authors:Fanning, S.W, Walter, R, Horn, J.R.
Deposit date:2014-02-27
Release date:2014-09-03
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.
Protein Eng.Des.Sel., 27, 2014
7UJ7
DownloadVisualize
BU of 7uj7 by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with RU39411
Descriptor: 11alpha-{4-[2-(dimethylamino)ethoxy]phenyl}estra-1(10),2,4-triene-3,17beta-diol, Estrogen receptor
Authors:Fanning, S.W, Greene, G.L.
Deposit date:2022-03-30
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022
4Q13
DownloadVisualize
BU of 4q13 by Molmil
Apo Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant with a glucocorticoid receptor-interacting protein 1 NR box II peptide
Descriptor: Estrogen receptor, Glucocorticoid receptor-interacting protein 1 NR box II peptide
Authors:Fanning, S.W, Panchamukhi, S, Greene, G.L.
Deposit date:2014-04-02
Release date:2015-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Elife, 5, 2016
4PXM
DownloadVisualize
BU of 4pxm by Molmil
The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with Estradiol and a glucocorticoid receptor-interacting protein 1 NR box II peptide
Descriptor: ESTRADIOL, Estrogen receptor, Nuclear receptor coactivator 2
Authors:Fanning, S.W, Panchamukhi, S, Greene, G.L.
Deposit date:2014-03-24
Release date:2015-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Elife, 5, 2016
4Q50
DownloadVisualize
BU of 4q50 by Molmil
The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with 4-hydroxytamoxifen
Descriptor: 4-HYDROXYTAMOXIFEN, Estrogen receptor, SULFATE ION
Authors:Fanning, S.W, Greene, G.L.
Deposit date:2014-04-15
Release date:2015-04-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Elife, 5, 2016
8JHW
DownloadVisualize
BU of 8jhw by Molmil
The first crystal structure of a H-2Kb-restricted decapeptide from Cryptosporidium parvum
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
Authors:Fan, S, Wang, Y.
Deposit date:2023-05-25
Release date:2024-05-29
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:The first crystal structure of a H-2Kb-restricted decapeptide from Cryptosporidium parvum
To Be Published
8JHV
DownloadVisualize
BU of 8jhv by Molmil
The first crystal structure of a H-2Kb-restricted decapeptide from Cryptosporidium parvum
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ...
Authors:Fan, S, Wang, Y, Zhao, J.
Deposit date:2023-05-25
Release date:2024-05-29
Method:X-RAY DIFFRACTION (3.47 Å)
Cite:The first crystal structure of a H-2Kb-restricted decapeptide from Cryptosporidium parvum
To Be Published
8GZO
DownloadVisualize
BU of 8gzo by Molmil
Crystal structure of collagen heterotrimer with K, D, E, R residuesC
Descriptor: collagen-like peptide
Authors:Fan, S.
Deposit date:2022-09-27
Release date:2023-07-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Stability of collagen heterotrimer with same charge pattern and different charged residue identities.
Biophys.J., 122, 2023
8H0F
DownloadVisualize
BU of 8h0f by Molmil
Crystal structure of collagen heterotrimer with KD,ER and KE axial pairs
Descriptor: collagen-like peptide chain A, collagen-like peptide chain B, collagen-like peptide chain C
Authors:Fan, S.
Deposit date:2022-09-28
Release date:2023-07-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Stability of collagen heterotrimer with same charge pattern and different charged residue identities.
Biophys.J., 122, 2023
8H0E
DownloadVisualize
BU of 8h0e by Molmil
Crystal structure of collagen heterotrimer with KD, ER and KE axial pairs
Descriptor: collagen-like peptide chain A, collagen-like peptide chain B, collagen-like peptide chain C
Authors:Fan, S.
Deposit date:2022-09-28
Release date:2023-07-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Stability of collagen heterotrimer with same charge pattern and different charged residue identities.
Biophys.J., 122, 2023
7YRV
DownloadVisualize
BU of 7yrv by Molmil
Solution structures of a disulfide-directed multicyclic peptide with affinity for FGFR1
Descriptor: LF1
Authors:Fan, S.H, Wu, C.L.
Deposit date:2022-08-10
Release date:2023-08-16
Last modified:2024-09-04
Method:SOLUTION NMR
Cite:Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Peptide Ligands and Drugs.
J.Am.Chem.Soc., 145, 2023
7YRW
DownloadVisualize
BU of 7yrw by Molmil
Solution structures of a disulfide-directed multicyclic peptide with affinity for HER2
Descriptor: LH2
Authors:Fan, S.H, Wu, C.L.
Deposit date:2022-08-10
Release date:2023-08-16
Last modified:2024-09-04
Method:SOLUTION NMR
Cite:Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Peptide Ligands and Drugs.
J.Am.Chem.Soc., 145, 2023
7YRX
DownloadVisualize
BU of 7yrx by Molmil
Solution structures of a disulfide-directed multicyclic peptide with affinity for HER3
Descriptor: LH3
Authors:Fan, S.H, Wu, C.L.
Deposit date:2022-08-11
Release date:2023-08-16
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Peptide Ligands and Drugs.
J.Am.Chem.Soc., 145, 2023
8WW1
DownloadVisualize
BU of 8ww1 by Molmil
Cyclic peptide with affinity for HER3
Descriptor: HER3-1
Authors:Fan, S.H, Wu, C.L.
Deposit date:2023-10-24
Release date:2024-10-30
Method:SOLUTION NMR
Cite:Combinations of Disulfide-Directing Motifs in Tandem Enabling the De-sign and Discovery of Multicyclic Peptide Binders
To Be Published
8WVS
DownloadVisualize
BU of 8wvs by Molmil
The structure of CPPCXC motif
Descriptor: SER-CYS-PRO-PRO-CYS-LYS-CYS-GLY-TRP
Authors:Fan, S.H, Wu, C.L.
Deposit date:2023-10-24
Release date:2024-10-30
Method:SOLUTION NMR
Cite:Combinations of Disulfide-Directing Motifs in Tandem Enabling the De-sign and Discovery of Multicyclic Peptide Binders
To Be Published
8WW0
DownloadVisualize
BU of 8ww0 by Molmil
Cyclic peptide with affinity for ICOS
Descriptor: icos-1
Authors:Fan, S.H, Wu, C.L.
Deposit date:2023-10-24
Release date:2024-10-30
Method:SOLUTION NMR
Cite:Combinations of Disulfide-Directing Motifs in Tandem Enabling the De-sign and Discovery of Multicyclic Peptide Binders
To Be Published
3L6A
DownloadVisualize
BU of 3l6a by Molmil
Crystal structure of the C-terminal region of Human p97
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Eukaryotic translation initiation factor 4 gamma 2, ...
Authors:Fan, S.
Deposit date:2009-12-23
Release date:2010-04-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the C-terminal region of human p97/DAP5.
Proteins, 78, 2010
8GUC
DownloadVisualize
BU of 8guc by Molmil
Solution structures of a disulfide-rich peptide selected via Cellular Protein Quality Control
Descriptor: xm63
Authors:Fan, S.H, Wu, C.L.
Deposit date:2022-09-11
Release date:2023-09-13
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:selection and evolution of Disulfide-rich peptides via cellular protein quality control
To Be Published
6K34
DownloadVisualize
BU of 6k34 by Molmil
Crystal Structure of DphMB1
Descriptor: Lipase
Authors:Fan, S.
Deposit date:2019-05-16
Release date:2020-06-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of DphMB1
To Be Published

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon