4GRR
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![BU of 4grr by Molmil](/molmil-images/mine/4grr) | characterization of N- and C- terminus mutants of human MIF | Descriptor: | (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor, ... | Authors: | Fan, C, Lolis, E. | Deposit date: | 2012-08-26 | Release date: | 2013-09-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Characterization of N- and C- terminus mutants of human MIF To be Published
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4GUM
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![BU of 4gum by Molmil](/molmil-images/mine/4gum) | Cystal structure of locked-trimer of human MIF | Descriptor: | CHLORIDE ION, Macrophage migration inhibitory factor | Authors: | Fan, C, Lolis, E. | Deposit date: | 2012-08-29 | Release date: | 2013-07-03 | Last modified: | 2020-11-18 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations. Proc.Natl.Acad.Sci.USA, 110, 2013
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7S7V
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![BU of 7s7v by Molmil](/molmil-images/mine/7s7v) | Crystal structure of iNicSnFR3a Fluorescent Nicotine Sensor | Descriptor: | iNicSnFR 3.0 Fluorescent Nicotine Sensor | Authors: | Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands. Elife, 11, 2022
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7S7T
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![BU of 7s7t by Molmil](/molmil-images/mine/7s7t) | iNicSnFR3a Nicotine Sensor comprising Periplasmic Binding sequence plus Fluorescent Sequence with varenicline bound | Descriptor: | IODIDE ION, VARENICLINE, iNicSnFR 3.0 Fluorescent Nicotine Sensor | Authors: | Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands. Elife, 11, 2022
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7S7U
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![BU of 7s7u by Molmil](/molmil-images/mine/7s7u) | Crystal structure of iNicSnFR3a Fluorescent Nicotine Sensor with nicotine bound | Descriptor: | iNicSnFR 3.0 Fluorescent Nicotine Sensor | Authors: | Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands. Elife, 11, 2022
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7SC1
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![BU of 7sc1 by Molmil](/molmil-images/mine/7sc1) | |
7S7Y
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![BU of 7s7y by Molmil](/molmil-images/mine/7s7y) | Crystal structure of iCytSnFR Cytisine Sensor precursor binding protein | Descriptor: | IMIDAZOLE, iNicSnFR 4.0 Fluorescent Nicotine Sensor precursor binding protein | Authors: | Fan, C, Nichols, N.L, Luebbert, L, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure, Function, and Application of Bacterial ABC Transporters Ph.D.Thesis,California Institute of Technology, 2020
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7S7Z
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![BU of 7s7z by Molmil](/molmil-images/mine/7s7z) | Crystal structure of iAChSnFR Acetylcholine Sensor precursor binding protein with choline bound | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHOLINE ION, iAchSnFR Fluorescent Acetylcholine Sensor precursor binding protein | Authors: | Fan, C, Borden, P.M, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure, Function, and Application of Bacterial ABC Transporters Ph.D.Thesis,California Institute of Technology, 2020
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7S7W
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![BU of 7s7w by Molmil](/molmil-images/mine/7s7w) | Crystal structure of iNicSnFR3a Nicotine Sensor precursor binding protein | Descriptor: | 1,2-ETHANEDIOL, SODIUM ION, iNicSnFR 3.0 Fluorescent Nicotine Sensor precursor binding protein | Authors: | Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structure, Function, and Application of Bacterial ABC Transporters Ph.D.Thesis,California Institute of Technology, 2020
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7S80
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![BU of 7s80 by Molmil](/molmil-images/mine/7s80) | Crystal structure of iAChSnFR Acetylcholine Sensor precursor binding protein | Descriptor: | 1,2-ETHANEDIOL, MALONATE ION, iAchSnFR Fluorescent Acetylcholine Sensor precursor binding protein | Authors: | Fan, C, Borden, P.M, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure, Function, and Application of Bacterial ABC Transporters Ph.D.Thesis,California Institute of Technology, 2020
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7S7X
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![BU of 7s7x by Molmil](/molmil-images/mine/7s7x) | Crystal structure of iCytSnFR Cytisine Sensor precursor binding protein with varenicline bound | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, DI(HYDROXYETHYL)ETHER, VARENICLINE, ... | Authors: | Fan, C, Nichols, N.L, Luebbert, L, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure, Function, and Application of Bacterial ABC Transporters Ph.D.Thesis,California Institute of Technology, 2020
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6C5W
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![BU of 6c5w by Molmil](/molmil-images/mine/6c5w) | Crystal structure of the mitochondrial calcium uniporter | Descriptor: | CALCIUM ION, calcium uniporter, nanobody | Authors: | Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L. | Deposit date: | 2018-01-17 | Release date: | 2018-07-11 | Last modified: | 2019-04-24 | Method: | X-RAY DIFFRACTION (3.10010242 Å) | Cite: | X-ray and cryo-EM structures of the mitochondrial calcium uniporter. Nature, 559, 2018
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6C5R
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![BU of 6c5r by Molmil](/molmil-images/mine/6c5r) | Crystal structure of the soluble domain of the mitochondrial calcium uniporter | Descriptor: | calcium uniporter | Authors: | Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L. | Deposit date: | 2018-01-16 | Release date: | 2018-07-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.09608316 Å) | Cite: | X-ray and cryo-EM structures of the mitochondrial calcium uniporter. Nature, 559, 2018
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7N59
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![BU of 7n59 by Molmil](/molmil-images/mine/7n59) | Structure of AtAtm3 in the inward-facing conformation with GSSG bound | Descriptor: | ABC transporter B family member 25, mitochondrial, OXIDIZED GLUTATHIONE DISULFIDE | Authors: | Fan, C, Rees, D.C. | Deposit date: | 2021-06-05 | Release date: | 2022-04-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters. Elife, 11, 2022
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6U5R
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![BU of 6u5r by Molmil](/molmil-images/mine/6u5r) | Calcium-bound MthK closed state | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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6U5P
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![BU of 6u5p by Molmil](/molmil-images/mine/6u5p) | Calcium-bound MthK gating ring state 1 | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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6U68
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![BU of 6u68 by Molmil](/molmil-images/mine/6u68) | |
6U6D
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![BU of 6u6d by Molmil](/molmil-images/mine/6u6d) | MthK closed state with EDTA | Descriptor: | Calcium-gated potassium channel MthK, POTASSIUM ION | Authors: | Fan, C, Rheinberger, J, Nimigean, C.M. | Deposit date: | 2019-08-29 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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6U5N
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![BU of 6u5n by Molmil](/molmil-images/mine/6u5n) | Calcium-bound MthK gating ring state 2 | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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6U6E
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![BU of 6u6e by Molmil](/molmil-images/mine/6u6e) | |
7UZ9
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![BU of 7uz9 by Molmil](/molmil-images/mine/7uz9) | |
7UZ8
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![BU of 7uz8 by Molmil](/molmil-images/mine/7uz8) | |
7UZA
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![BU of 7uza by Molmil](/molmil-images/mine/7uza) | |
7UZ5
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![BU of 7uz5 by Molmil](/molmil-images/mine/7uz5) | |
7UZ6
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![BU of 7uz6 by Molmil](/molmil-images/mine/7uz6) | |