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PDB: 24 件

9EME
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AL amyloid fibril from the FOR103 light chain
分子名称: lambda 3 immunoglobulin light chain fragment, residues 2-116
著者Pfeiffer, P.B, Karimi-Farsijani, S, Kupfer, N, Schmidt, M, Faendrich, M.
登録日2024-03-08
公開日2024-06-26
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis.
Nat Commun, 15, 2024
8B3A
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catalytic amyloid fibril formed by Ac-LHLHLRL-amide
分子名称: ACE-LEU-HIS-LEU-HIS-LEU-ARG-LEU-NH2
著者Heerde, T, Schmidt, M, Faendrich, M.
登録日2022-09-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of a catalytic amyloid fibril.
Sci Rep, 13, 2023
8QX9
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TDP-43 amyloid fibrils: Morphology-1a
分子名称: TAR DNA-binding protein 43
著者Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M.
登録日2023-10-24
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils.
Nat Commun, 15, 2024
7ZKY
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Amyloid fibril from human systemic AA amyloidosis (vascular variant)
分子名称: Amyloid protein A
著者Banerjee, S, Schmidt, M, Faendrich, M.
登録日2022-04-13
公開日2022-12-07
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献Amyloid fibril structure from the vascular variant of systemic AA amyloidosis.
Nat Commun, 13, 2022
8R47
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AL amyloid fibril from the FOR010 light chain
分子名称: lambda 3 immunoglobulin light chain fragment, residues 4-116
著者Pfeiffer, P.B, Banerjee, S, Schmidt, M, Faendrich, M.
登録日2023-11-13
公開日2024-06-26
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.25 Å)
主引用文献Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis.
Nat Commun, 15, 2024
7ZJ2
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Amyloid fibril (in vitro) from full-length hnRNPA1 protein
分子名称: Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1
著者Sharma, K, Banerjee, S, Schmidt, M, Faendrich, M.
登録日2022-04-08
公開日2023-08-02
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril.
J.Mol.Biol., 435, 2023
6ZCH
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Amyloid fibril morphology II (ex vivo) from murine SAA1.1 protein.
分子名称: Serum amyloid A-2 protein
著者Bansal, A, Schmidt, M, Faendrich, M.
登録日2020-06-11
公開日2021-02-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils.
Nat Commun, 12, 2021
6ZCF
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Amyloid fibril morphology i (in vitro) from murine SAA1.1 protein
分子名称: Serum amyloid A-2 protein
著者Bansal, A, Schmidt, M, Faendrich, M.
登録日2020-06-11
公開日2021-02-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils.
Nat Commun, 12, 2021
8OQ4
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AApoAII amyloid fibril Morphology II (ex vivo)
分子名称: Apolipoprotein A-II
著者Andreotti, G, Schmidt, M, Faendrich, M.
登録日2023-04-11
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Insights into the Structural Basis of Amyloid Resistance Provided by Cryo-EM Structures of AApoAII Amyloid Fibrils.
J.Mol.Biol., 436, 2024
7OVT
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major seeded in vitro fibril morphology from murine SAA1.1 protein
分子名称: Serum amyloid A-2 protein
著者Heerde, T, Schmidt, M, Faendrich, M.
登録日2021-06-15
公開日2022-02-02
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology by seeding.
Nat Commun, 13, 2022
8OT3
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unseeded Abeta(1-40) amyloid fibril (morphology ii)
分子名称: Amyloid-beta A4 protein
著者Pfeiffer, P.B, Schmidt, M, Faendrich, M.
登録日2023-04-20
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Cryo-EM Analysis of the Effect of Seeding with Brain-derived A beta Amyloid Fibrils.
J.Mol.Biol., 436, 2023
8OT1
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unseeded Abeta(1-40) amyloid fibril (morphology i)
分子名称: Amyloid-beta A4 protein
著者Pfeiffer, P.B, Schmidt, M, Faendrich, M.
登録日2023-04-20
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Cryo-EM Analysis of the Effect of Seeding with Brain-derived A beta Amyloid Fibrils.
J.Mol.Biol., 436, 2023
8OT4
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seeded Abeta(1-40) amyloid fibril (morphology I)
分子名称: Amyloid-beta A4 protein
著者Pfeiffer, P.B, Schmidt, M, Faendrich, M.
登録日2023-04-20
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Cryo-EM Analysis of the Effect of Seeding with Brain-derived A beta Amyloid Fibrils.
J.Mol.Biol., 436, 2023
8OQ5
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AApoAII amyloid fibril Morphology I (ex vivo)
分子名称: Apolipoprotein A-II
著者Andreotti, G, Schmidt, M, Faendrich, M.
登録日2023-04-11
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Insights into the Structural Basis of Amyloid Resistance Provided by Cryo-EM Structures of AApoAII Amyloid Fibrils.
J.Mol.Biol., 436, 2024
8PKE
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BU of 8pke by Molmil
ATTRV20I amyloid fibril from hereditary ATTR amloidosis
分子名称: Transthyretin
著者Steinebrei, M, Schmidt, M, Faendrich, M.
登録日2023-06-26
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis.
Nat Commun, 14, 2023
8PKG
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ATTRV122I amyloid fibril from hereditary ATTR amloidosis
分子名称: Transthyretin
著者Steinebrei, M, Schmidt, M, Faendrich, M.
登録日2023-06-26
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis.
Nat Commun, 14, 2023
5L6Q
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Refolded AL protein from cardiac amyloidosis
分子名称: CARBONATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Annamalai, K, Liberta, F, Vielberg, M.-T, Lilie, H, Guehrs, K.-H, Schierhorn, A, Koehler, R, Schmidt, A, Haupt, C, Hegenbart, O, Schoenland, S, Groll, M, Faendrich, M.
登録日2016-05-31
公開日2017-05-31
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo.
Angew. Chem. Int. Ed. Engl., 56, 2017
8PKF
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ATTRG47E amyloid fibril from hereditary ATTR amloidosis
分子名称: Transthyretin
著者Steinebrei, M, Schmidt, M, Faendrich, M.
登録日2023-06-26
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.3673 Å)
主引用文献Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis.
Nat Commun, 14, 2023
8OKR
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virus enhancing amyloid fibril formed by CKFKFQF
分子名称: PNF-18
著者Heerde, T, Schmidt, M, Faendrich, M.
登録日2023-03-29
公開日2023-08-02
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Cryo-EM structure and polymorphic maturation of a viral transduction enhancing amyloid fibril.
Nat Commun, 14, 2023
8QXB
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TDP-43 amyloid fibrils: Morphology-2
分子名称: TAR DNA-binding protein 43
著者Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M.
登録日2023-10-24
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils.
Nat Commun, 15, 2024
8QXA
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TDP-43 amyloid fibrils: Morphology-1b
分子名称: TAR DNA-binding protein 43
著者Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M.
登録日2023-10-24
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils.
Nat Commun, 15, 2024
3LN9
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Crystal structure of the fibril-specific B10 antibody fragment
分子名称: CITRATE ANION, GLYCEROL, Immunoglobulin heavy chain antibody variable domain B10, ...
著者Parthier, C, Morgado, I, Stubbs, M.T, Faendrich, M.
登録日2010-02-02
公開日2010-12-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Amyloid Fibril Recognition with the Conformational B10 Antibody Fragment Depends on Electrostatic Interactions.
J.Mol.Biol., 2010
6SDZ
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transthyritin derived amyloid fibril from patient with hereditary V30M ATTR amyloidosis
分子名称: Transthyretin
著者Fritz, G, Agarwal, S, Faendrich, M.
登録日2019-07-29
公開日2019-11-13
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis.
Nat Commun, 10, 2019
6IC3
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AL amyloid fibril from a lambda 1 light chain
分子名称: lambda 1 light chain fragment, residues 3-118
著者Fritz, G, Faendrich, M, Schmidt, M, Radamaker, L.
登録日2018-12-02
公開日2019-04-03
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis.
Nat Commun, 10, 2019

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