8QXB
TDP-43 amyloid fibrils: Morphology-2
Summary for 8QXB
| Entry DOI | 10.2210/pdb8qxb/pdb |
| EMDB information | 18717 |
| Descriptor | TAR DNA-binding protein 43 (1 entity in total) |
| Functional Keywords | amyloidosis, protein misfolding disease, amyloid fibrils, cryo electron microscopy, amyloid key, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 18 |
| Total formula weight | 806125.36 |
| Authors | Sharma, K.,Shenoy, J.,Loquet, A.,Schmidt, M.,Faendrich, M. (deposition date: 2023-10-24, release date: 2024-01-24) |
| Primary citation | Sharma, K.,Stockert, F.,Shenoy, J.,Berbon, M.,Abdul-Shukkoor, M.B.,Habenstein, B.,Loquet, A.,Schmidt, M.,Fandrich, M. Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils. Nat Commun, 15:486-486, 2024 Cited by PubMed: 38212334DOI: 10.1038/s41467-023-44489-0 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.86 Å) |
Structure validation
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