6IC3
AL amyloid fibril from a lambda 1 light chain
Summary for 6IC3
| Entry DOI | 10.2210/pdb6ic3/pdb |
| EMDB information | 4452 |
| Descriptor | lambda 1 light chain fragment, residues 3-118 (1 entity in total) |
| Functional Keywords | amyloid fibril, beta sheet, antibody, heart, protein fibril |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 8 |
| Total formula weight | 97419.70 |
| Authors | Fritz, G.,Faendrich, M.,Schmidt, M.,Radamaker, L. (deposition date: 2018-12-02, release date: 2019-04-03, Last modification date: 2019-12-18) |
| Primary citation | Radamaker, L.,Lin, Y.H.,Annamalai, K.,Huhn, S.,Hegenbart, U.,Schonland, S.O.,Fritz, G.,Schmidt, M.,Fandrich, M. Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis. Nat Commun, 10:1103-1103, 2019 Cited by PubMed: 30894526DOI: 10.1038/s41467-019-09032-0 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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