6SDZ

transthyritin derived amyloid fibril from patient with hereditary V30M ATTR amyloidosis

Summary for 6SDZ

• Entry DOI: 10.2210/pdb6sdz/pdb
• EMDB information: 10150
• Descriptor: Transthyretin (1 entity in total)
• Functional Keywords: amyloid fibril, systemic attr amyloidosis, ex vivo, misfolding, patient tissue, transthyritin, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 11
• Total formula weight: 151903.69

Authors

Fritz, G.,Agarwal, S.,Faendrich, M. (deposition date: 2019-07-29, release date: 2019-11-13, Last modification date: 2024-05-22)

• Primary citation: Schmidt, M.,Wiese, S.,Adak, V.,Engler, J.,Agarwal, S.,Fritz, G.,Westermark, P.,Zacharias, M.,Fandrich, M.; Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis.; Nat Commun, 10:5008-5008, 2019; PubMed: 31676763; DOI: 10.1038/s41467-019-13038-z

Experimental method