4E0K
 
 | | Crystal Structure of the amyloid-fibril forming peptide KDWSFY derived from human Beta 2 Microglobulin (58-63) | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Amyloidogenic peptide segment KDWSFY, SODIUM ION | | 著者 | Zhao, M, Liu, C, Sawaya, M.R, Eisenberg, D. | | 登録日 | 2012-03-04 | | 公開日 | 2012-12-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | | 主引用文献 | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5DBN
 | | Crystal structure of AtoDA complex | | 分子名称: | Acetate CoA-transferase subunit alpha, Acetate CoA-transferase subunit beta, CHLORIDE ION, ... | | 著者 | Arbing, M.A, Koo, C.W, Shin, A, Medrano-Soto, A, Eisenberg, D. | | 登録日 | 2015-08-21 | | 公開日 | 2016-08-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.549 Å) | | 主引用文献 | Crystal structure of AtoDA complex
To Be Published
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5E61
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5E5X
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5E5V
 | | Structure of amyloid forming peptide NFGAILS (residues 22-28) from Islet Amyloid Polypeptide | | 分子名称: | NFGAILS (22-28) from islet amyloid polypeptide, synthesized | | 著者 | Soriaga, A.B, Macdonald, R, Sawaya, M.R, Sangwan, S, Eisenberg, D. | | 登録日 | 2015-10-09 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
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5E5Z
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5DB5
 | | Crystal structure of PLP-bound E. coli SufS (cysteine persulfide intermediate) in space group P21 | | 分子名称: | 1,2-ETHANEDIOL, CITRIC ACID, CYSTEINE, ... | | 著者 | Arbing, M.A, Shin, A, Koo, C.W, Medrano-Soto, A, Eisenberg, D. | | 登録日 | 2015-08-20 | | 公開日 | 2016-08-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal structure of PLP-bound E. coli SufS (cysteine persulfide intermediate) in space group P21
To Be Published
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4QX0
 | | Cry3A Toxin structure obtained by Serial Femtosecond Crystallography from in vivo grown crystals isolated from Bacillus thuringiensis and data processed with the cctbx.xfel software suite | | 分子名称: | Pesticidal crystal protein cry3Aa | | 著者 | Sawaya, M.R, Cascio, D, Gingery, M, Rodriguez, J, Goldschmidt, L, Colletier, J.-P, Messerschmidt, M, Boutet, S, Koglin, J.E, Williams, G.J, Brewster, A.S, Nass, K, Hattne, J, Botha, S, Doak, R.B, Shoeman, R.L, DePonte, D.P, Park, H.-W, Federici, B.A, Sauter, N.K, Schlichting, I, Eisenberg, D. | | 登録日 | 2014-07-17 | | 公開日 | 2014-08-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4GZR
 | | Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP (Rv2346c-Rv2347c) complex in space group C2221 | | 分子名称: | ESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION | | 著者 | Arbing, M.A, Chan, S, He, Q, Harris, L, Zhou, T.T, Kuo, E, Ahn, C.J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI) | | 登録日 | 2012-09-06 | | 公開日 | 2012-09-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.553 Å) | | 主引用文献 | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
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4QX3
 | | Cry3A Toxin structure obtained by injecting Bacillus thuringiensis cells in an XFEL beam, collecting data by serial femtosecond crystallographic methods and processing data with the CrystFEL software suite | | 分子名称: | Pesticidal crystal protein cry3Aa | | 著者 | Sawaya, M.R, Cascio, D, Gingery, M, Rodriguez, J, Goldschmidt, L, Colletier, J.-P, Messerschmidt, M, Boutet, S, Koglin, J.E, Williams, G.J, Brewster, A.S, Nass, K, Hattne, J, Botha, S, Doak, R.B, Shoeman, R.L, DePonte, D.P, Park, H.-W, Federici, B.A, Sauter, N.K, Schlichting, I, Eisenberg, D. | | 登録日 | 2014-07-17 | | 公開日 | 2014-08-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4QX2
 | | Cry3A Toxin structure obtained by injecting Bacillus thuringiensis cells in an XFEL beam, collecting data by serial femtosecond crystallographic methods and processing data with the cctbx.xfel software suite | | 分子名称: | Pesticidal crystal protein cry3Aa | | 著者 | Sawaya, M.R, Cascio, D, Gingery, M, Rodriguez, J, Goldschmidt, L, Colletier, J.-P, Messerschmidt, M, Boutet, S, Koglin, J.E, Williams, G.J, Brewster, A.S, Nass, K, Hattne, J, Botha, S, Doak, R.B, Shoeman, R.L, DePonte, D.P, Park, H.-W, Federici, B.A, Sauter, N.K, Schlichting, I, Eisenberg, D. | | 登録日 | 2014-07-17 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4E0N
 | | SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form II) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION | | 著者 | Zhao, M, Liu, C, Michael, S.R, Eisenberg, D. | | 登録日 | 2012-03-04 | | 公開日 | 2012-12-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4E0O
 | | SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form III) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION | | 著者 | Zhao, M, Liu, C, Sawaya, M.R, Eisenberg, D. | | 登録日 | 2012-03-04 | | 公開日 | 2012-12-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4E0M
 | | SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form I) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION | | 著者 | Zhao, M, Liu, C, Michael, S.R, Eisenberg, D. | | 登録日 | 2012-03-04 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Out-of-register beta-sheets suggest a pathway
to toxic amyloid aggregates
Proc.Natl.Acad.Sci.USA, 109, 2012
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4RUB
 | | A CRYSTAL FORM OF RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE FROM NICOTIANA TABACUM IN THE ACTIVATED STATE | | 分子名称: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, FORMIC ACID, MAGNESIUM ION, ... | | 著者 | Schreuder, H, Cascio, D, Curmi, P.M.G, Eisenberg, D. | | 登録日 | 1990-05-25 | | 公開日 | 1992-10-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A crystal form of ribulose-1,5-bisphosphate carboxylase/oxygenase from Nicotiana tabacum in the activated state.
J.Mol.Biol., 197, 1987
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3NHC
 | | GYMLGS segment 127-132 from human prion with M129 | | 分子名称: | Major prion protein | | 著者 | Apostol, M.I, Eisenberg, D. | | 登録日 | 2010-06-14 | | 公開日 | 2010-08-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease.
J.Biol.Chem., 285, 2010
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1LNX
 | | Crystal structure of the P.aerophilum SmAP1 heptamer in a new crystal form (C2221) | | 分子名称: | ACETIC ACID, GLYCEROL, URIDINE, ... | | 著者 | Mura, C, Kozhukhovsky, A, Eisenberg, D. | | 登録日 | 2002-05-04 | | 公開日 | 2003-03-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
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3NHD
 | | GYVLGS segment 127-132 from human prion with V129 | | 分子名称: | ACETIC ACID, Major prion protein | | 著者 | Apostol, M.I, Eisenberg, D. | | 登録日 | 2010-06-14 | | 公開日 | 2010-08-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease.
J.Biol.Chem., 285, 2010
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3MML
 | | Allophanate Hydrolase Complex from Mycobacterium smegmatis, Msmeg0435-Msmeg0436 | | 分子名称: | Allophanate hydrolase subunit 1, Allophanate hydrolase subunit 2, CHLORIDE ION | | 著者 | Kaufmann, M, Chernishof, I, Shin, A, Germano, D, Sawaya, M.R, Waldo, G.S, Arbing, M.A, Perry, J, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2010-04-20 | | 公開日 | 2010-04-28 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of Allphanate Hydrolase Complex from M. smegmatis, Msmeg0435-Msmeg0436
To be Published
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3NVH
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1Z6K
 | | Citrate lyase beta subunit complexed with oxaloacetate and magnesium from M. tuberculosis | | 分子名称: | Citrate Lyase beta subunit, MAGNESIUM ION, OXALOACETATE ION | | 著者 | Goulding, C.W, Bowers, P.M, Segelke, B, Lekin, T, Kim, C.Y, Terwilliger, T.C, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2005-03-22 | | 公開日 | 2005-05-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function.
J.Mol.Biol., 365, 2007
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1LOJ
 | | Crystal structure of a Methanobacterial Sm-like archaeal protein (SmAP1) bound to uridine-5'-monophosphate (UMP) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, URIDINE, URIDINE-5'-MONOPHOSPHATE, ... | | 著者 | Mura, C, Kozhukhovsky, A, Eisenberg, D. | | 登録日 | 2002-05-06 | | 公開日 | 2003-03-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
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4I0X
 | | Crystal structure of the Mycobacterum abscessus EsxEF (Mab_3112-Mab_3113) complex | | 分子名称: | BETA-MERCAPTOETHANOL, ESAT-6-like protein MAB_3112, ESAT-6-like protein MAB_3113, ... | | 著者 | Arbing, M.A, Chan, S, Lu, J, Kuo, E, Harris, L, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2012-11-19 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.956 Å) | | 主引用文献 | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
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1I8F
 | | THE CRYSTAL STRUCTURE OF A HEPTAMERIC ARCHAEAL SM PROTEIN: IMPLICATIONS FOR THE EUKARYOTIC SNRNP CORE | | 分子名称: | GLYCEROL, PUTATIVE SNRNP SM-LIKE PROTEIN | | 著者 | Mura, C, Cascio, D, Sawaya, M.R, Eisenberg, D. | | 登録日 | 2001-03-14 | | 公開日 | 2001-05-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP core.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1EWF
 | | THE 1.7 ANGSTROM CRYSTAL STRUCTURE OF BPI | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN | | 著者 | Kleiger, G, Beamer, L.J, Grothe, R, Mallick, P, Eisenberg, D. | | 登録日 | 2000-04-25 | | 公開日 | 2000-06-21 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The 1.7 A crystal structure of BPI: a study of how two dissimilar amino acid sequences can adopt the same fold.
J.Mol.Biol., 299, 2000
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