1S4Q
 
 | | Crystal Structure of Guanylate Kinase from Mycobacterium tuberculosis (Rv1389) | | 分子名称: | CHLORIDE ION, FORMIC ACID, Guanylate kinase | | 著者 | Chan, S, Sawaya, M.R, Perry, L.J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2004-01-16 | | 公開日 | 2004-01-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Crystal Structure of Guanylate Kinase from Mycobacterium tuberculosis
To be Published
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4RIL
 | | Structure of the amyloid forming segment, GAVVTGVTAVA, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 68-78, determined by electron diffraction | | 分子名称: | Alpha-synuclein | | 著者 | Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S. | | 登録日 | 2014-10-06 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.43 Å) | | 主引用文献 | Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
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3OEI
 | | Crystal structure of Mycobacterium tuberculosis RelJK (Rv3357-Rv3358-RelBE3) | | 分子名称: | CITRATE ANION, RelJ (Antitoxin Rv3357), RelK (Toxin Rv3358) | | 著者 | Miallau, L, Cascio, D, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2010-08-12 | | 公開日 | 2011-03-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.145 Å) | | 主引用文献 | Comparative proteomics identifies the cell-associated lethality of M. tuberculosis RelBE-like toxin-antitoxin complexes.
Structure, 21, 2013
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1LNX
 | | Crystal structure of the P.aerophilum SmAP1 heptamer in a new crystal form (C2221) | | 分子名称: | ACETIC ACID, GLYCEROL, URIDINE, ... | | 著者 | Mura, C, Kozhukhovsky, A, Eisenberg, D. | | 登録日 | 2002-05-04 | | 公開日 | 2003-03-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
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1LOJ
 | | Crystal structure of a Methanobacterial Sm-like archaeal protein (SmAP1) bound to uridine-5'-monophosphate (UMP) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, URIDINE, URIDINE-5'-MONOPHOSPHATE, ... | | 著者 | Mura, C, Kozhukhovsky, A, Eisenberg, D. | | 登録日 | 2002-05-06 | | 公開日 | 2003-03-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
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1M5Q
 | | Crystal structure of a novel Sm-like archaeal protein from Pyrobaculum aerophilum | | 分子名称: | ACETIC ACID, CADMIUM ION, GLYCEROL, ... | | 著者 | Mura, C, Phillips, M, Kozhukhovsky, A, Eisenberg, D. | | 登録日 | 2002-07-09 | | 公開日 | 2003-03-18 | | 最終更新日 | 2017-05-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and assembly of an augmented Sm-like archaeal protein 14-mer
Proc.Natl.Acad.Sci.USA, 100, 2003
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4RIK
 | | Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77 | | 分子名称: | Alpha-synuclein | | 著者 | Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S. | | 登録日 | 2014-10-06 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.854 Å) | | 主引用文献 | Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
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4NP8
 | | Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate polymorph) | | 分子名称: | Microtubule-associated protein tau | | 著者 | Landau, M, Eisenberg, D, Sawaya, M.R, Dannenberg, J, Kobko, N. | | 登録日 | 2013-11-20 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Molecular mechanisms for protein-encoded inheritance.
Nat.Struct.Mol.Biol., 16, 2009
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4PM4
 | | Structure of a putative periplasmic iron siderophore binding protein (Rv0265c) from Mycobacterium tuberculosis H37Rv | | 分子名称: | CHLORIDE ION, Iron complex transporter substrate-binding protein, SULFATE ION | | 著者 | Arbing, M.A, Chan, S, Tran, N, Kuo, E, Lu, J, Harris, L.R, Zhou, T.T, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2014-05-20 | | 公開日 | 2014-06-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a putative periplasmic iron siderophore binding protein (Rv0265c) from Mycobacterium tuberculosis H37Rv
To Be Published
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4R0U
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4R0W
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6BZP
 | | STGGYG from low-complexity domain of FUS, residues 77-82 | | 分子名称: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, RNA-binding protein FUS | | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S. | | 登録日 | 2017-12-25 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.1 Å) | | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
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6BZM
 | | GFGNFGTS from low-complexity/FG repeat domain of Nup98, residues 116-123 | | 分子名称: | Nuclear pore complex protein Nup98-Nup96 | | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Chong, L, Gonen, T, Eisenberg, D.S. | | 登録日 | 2017-12-24 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.9 Å) | | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
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6BXX
 | | GYNGFG from low-complexity domain of hnRNPA1, residues 243-248 | | 分子名称: | hnRNPA1 | | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S. | | 登録日 | 2017-12-19 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
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6CU7
 | | Alpha Synuclein fibril formed by full length protein - Rod Polymorph | | 分子名称: | Alpha-synuclein | | 著者 | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | | 登録日 | 2018-03-23 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
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6CF4
 | | Segment NFGTFS, with familial mutation A315T and phosphorylated threonine, from the low complexity domain of TDP-43, residues 312-317 | | 分子名称: | NFGTFS | | 著者 | Guenther, E.L, Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2018-02-13 | | 公開日 | 2018-05-23 | | 最終更新日 | 2021-06-30 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.75 Å) | | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
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6CU8
 | | Alpha Synuclein fibril formed by full length protein - Twister Polymorph | | 分子名称: | Alpha-synuclein | | 著者 | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | | 登録日 | 2018-03-23 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
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4R0P
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6AS9
 | | Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of 18-residues, viewed in space group P212121 form 2 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Green fluorescent protein | | 著者 | Sawaya, M.R, Heller, D.M, McPartland, L, Hochschild, A, Eisenberg, D.S. | | 登録日 | 2017-08-23 | | 公開日 | 2018-05-30 | | 最終更新日 | 2019-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Atomic insights into the genesis of cellular filaments by globular proteins.
Nat. Struct. Mol. Biol., 25, 2018
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6BCS
 | | LilrB2 D1D2 domains complexed with benzamidine | | 分子名称: | BENZAMIDINE, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Cao, Q, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2017-10-20 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Inhibiting amyloid-beta cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design.
Nat Chem, 10, 2018
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6BWZ
 | | SYSGYS from low-complexity domain of FUS, residues 37-42 | | 分子名称: | SYSGYS peptide from low-complexity domain of FUS | | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Tamir, G, Eisenberg, D.S. | | 登録日 | 2017-12-15 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
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6BXV
 | | SYSSYGQS from low-complexity domain of FUS, residues 54-61 | | 分子名称: | FUS | | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S. | | 登録日 | 2017-12-19 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
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6CFH
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6CB9
 | | Segment AALQSS from the low complexity domain of TDP-43, residues 328-333 | | 分子名称: | AALQSS | | 著者 | Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2018-02-02 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
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6CEW
 | | Segment AMMAAA from the low complexity domain of TDP-43, residues 321-326 | | 分子名称: | AMMAAA | | 著者 | Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2018-02-12 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
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