5X3S
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5XDA
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5Y7K
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![BU of 5y7k by Molmil](/molmil-images/mine/5y7k) | Crystal structure of human DPP4 in complex with inhibitor1 | Descriptor: | (R)-4-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazine-2-one, Dipeptidyl peptidase 4 | Authors: | Lee, H.K, Kim, E.E. | Deposit date: | 2017-08-17 | Release date: | 2019-03-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.512 Å) | Cite: | Unique binding mode of Evogliptin with human dipeptidyl peptidase IV. Biochem.Biophys.Res.Commun., 494, 2017
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5Y7J
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![BU of 5y7j by Molmil](/molmil-images/mine/5y7j) | Crystal structure of human DPP4 in complex with inhibitor2 | Descriptor: | (S)-4-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazin-2-one, Dipeptidyl peptidase 4 | Authors: | Lee, H.K, Kim, E.E. | Deposit date: | 2017-08-17 | Release date: | 2019-03-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.521 Å) | Cite: | Unique binding mode of Evogliptin with human dipeptidyl peptidase IV. Biochem.Biophys.Res.Commun., 494, 2017
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5Y7H
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![BU of 5y7h by Molmil](/molmil-images/mine/5y7h) | Crystal structure of human DPP4 in complex with inhibitor3 | Descriptor: | (R)-4-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)piperazin-2-one, Dipeptidyl peptidase 4 | Authors: | Lee, H.K, Kim, E.E. | Deposit date: | 2017-08-17 | Release date: | 2019-03-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Unique binding mode of Evogliptin with human dipeptidyl peptidase IV. Biochem.Biophys.Res.Commun., 494, 2017
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5WTH
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![BU of 5wth by Molmil](/molmil-images/mine/5wth) | Cryo-EM structure for Hepatitis A virus complexed with FAB | Descriptor: | FAB Heavy Chain, FAB Light Chain, Polyprotein, ... | Authors: | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | Deposit date: | 2016-12-12 | Release date: | 2017-01-25 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WTF
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![BU of 5wtf by Molmil](/molmil-images/mine/5wtf) | Cryo-EM structure for Hepatitis A virus empty particle | Descriptor: | VP0, VP1, VP3 | Authors: | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | Deposit date: | 2016-12-11 | Release date: | 2017-01-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WTE
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![BU of 5wte by Molmil](/molmil-images/mine/5wte) | Cryo-EM structure for Hepatitis A virus full particle | Descriptor: | VP1, VP2, VP3 | Authors: | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | Deposit date: | 2016-12-11 | Release date: | 2017-01-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WTG
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![BU of 5wtg by Molmil](/molmil-images/mine/5wtg) | Crystal structure of the Fab fragment of anti-HAV antibody R10 | Descriptor: | FAB Heavy chain, FAB Light chain | Authors: | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | Deposit date: | 2016-12-11 | Release date: | 2017-01-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.907 Å) | Cite: | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WSN
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![BU of 5wsn by Molmil](/molmil-images/mine/5wsn) | Structure of Japanese encephalitis virus | Descriptor: | E protein, M protein | Authors: | Wang, X, Zhu, L, Li, S, Yuan, S, Qin, C, Fry, E.E, Stuart, I.D, Rao, Z. | Deposit date: | 2016-12-07 | Release date: | 2017-05-17 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability Nat Commun, 8, 2017
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5ZQM
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5ZQL
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4HSI
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4HQH
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4I8V
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4FDK
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![BU of 4fdk by Molmil](/molmil-images/mine/4fdk) | F78L Tt H-NOX | Descriptor: | Methyl-accepting chemotaxis protein, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Weinert, E.E, Phillips-Piro, C.M, Marletta, M.A. | Deposit date: | 2012-05-28 | Release date: | 2013-08-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Porphyrin pi-stacking in a heme protein scaffold tunes gas ligand affinity. J.Inorg.Biochem., 127C, 2013
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4GWM
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![BU of 4gwm by Molmil](/molmil-images/mine/4gwm) | Crystal structure of human promeprin beta | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Arolas, J.L, Broder, C, Jefferson, T, Guevara, T, Sterchi, E.E, Bode, W, Stocker, W, Becker-Pauly, C, Gomis-Ruth, F.X. | Deposit date: | 2012-09-03 | Release date: | 2012-09-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane Proc.Natl.Acad.Sci.USA, 109, 2012
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4GWN
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![BU of 4gwn by Molmil](/molmil-images/mine/4gwn) | Crystal structure of human mature meprin beta | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Arolas, J.L, Broder, C, Jefferson, T, Guevara, T, Sterchi, E.E, Bode, W, Stocker, W, Becker-Pauly, C, Gomis-Ruth, F.X. | Deposit date: | 2012-09-03 | Release date: | 2012-09-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane Proc.Natl.Acad.Sci.USA, 109, 2012
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4IRG
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![BU of 4irg by Molmil](/molmil-images/mine/4irg) | Uninhibited DNA-binding domain of the Ets transcription factor ERG | Descriptor: | Transcriptional regulator ERG | Authors: | Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H. | Deposit date: | 2013-01-14 | Release date: | 2013-07-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited. Proc.Natl.Acad.Sci.USA, 110, 2013
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4IRH
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![BU of 4irh by Molmil](/molmil-images/mine/4irh) | Auto-inhibited ERG Ets domain | Descriptor: | Transcriptional regulator ERG | Authors: | Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H. | Deposit date: | 2013-01-14 | Release date: | 2013-07-31 | Last modified: | 2013-08-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited. Proc.Natl.Acad.Sci.USA, 110, 2013
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4IRI
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![BU of 4iri by Molmil](/molmil-images/mine/4iri) | Auto-inhibited ERG Ets Domain-DNA Complex | Descriptor: | DNA (5'-D(*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*G)-3'), Transcriptional regulator ERG | Authors: | Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H. | Deposit date: | 2013-01-14 | Release date: | 2013-07-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited. Proc.Natl.Acad.Sci.USA, 110, 2013
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4IV1
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![BU of 4iv1 by Molmil](/molmil-images/mine/4iv1) | Crystal structure of recombinant foot-and-mouth-disease virus A22 empty capsid | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Porta, C, Kotecha, A, Burman, A, Jackson, T, Ren, J, Loureiro, S, Jones, I.M, Fry, E.E, Stuart, D.I, Charleston, B. | Deposit date: | 2013-01-22 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen. Plos Pathog., 9, 2013
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4IV3
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![BU of 4iv3 by Molmil](/molmil-images/mine/4iv3) | Crystal structure of recombinant foot-and-mouth-disease virus A22-H2093C empty capsid | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Porta, C, Kotecha, A, Burman, A, Jackson, T, Ren, J, Loureiro, S, Jones, I.M, Fry, E.E, Stuart, D.I, Charleston, B. | Deposit date: | 2013-01-22 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen. Plos Pathog., 9, 2013
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7KQ8
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![BU of 7kq8 by Molmil](/molmil-images/mine/7kq8) | Structure of iron bound MEMO1 | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FE (II) ION, ... | Authors: | Boniecki, M.T, Uhlemann, E.E, Dmitriev, O.Y. | Deposit date: | 2020-11-13 | Release date: | 2021-11-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | MEMO1 binds iron and modulates iron homeostasis in cancer cells. Elife, 13, 2024
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7KXS
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![BU of 7kxs by Molmil](/molmil-images/mine/7kxs) | Computational design of constitutively active cGAS | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | Authors: | Dowling, Q, Volkman, H.E, Gray, E.E, Ovchinnikov, S, Cambier, S, Bera, A.K, Bick, M, Kang, A, Stetson, D.B, King, N.P. | Deposit date: | 2020-12-04 | Release date: | 2021-12-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Computational design of constitutively active cGAS. Nat.Struct.Mol.Biol., 30, 2023
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