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4HSI

Glycoprotein B from Herpes simplex virus type 1, A504P/R505G/Q507G/N511G mutant, low-pH

Summary for 4HSI
Entry DOI10.2210/pdb4hsi/pdb
Related2gum 3nw8 3nwa 3nwd 3nwf
DescriptorEnvelope glycoprotein B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywordsviral fusion protein, viral envelope, viral protein
Biological sourceHuman herpesvirus 1 (HHV-1)
Cellular locationVirion membrane; Single-pass type I membrane protein (By similarity): P06437
Total number of polymer chains4
Total formula weight317350.48
Authors
Heldwein, E.E. (deposition date: 2012-10-30, release date: 2013-03-27, Last modification date: 2023-09-20)
Primary citationVitu, E.,Sharma, S.,Stampfer, S.D.,Heldwein, E.E.
Extensive Mutagenesis of the HSV-1 gB Ectodomain Reveals Remarkable Stability of Its Postfusion Form.
J.Mol.Biol., 425:2056-2071, 2013
Cited by
PubMed: 23500487
DOI: 10.1016/j.jmb.2013.03.001
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.101 Å)
Structure validation

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