4V0L
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7MDO
| Structure of human p97 ATPase L464P mutant | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. | 登録日 | 2021-04-05 | 公開日 | 2021-08-25 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | 主引用文献 | Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity. Biochem.J., 478, 2021
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4W8Y
| Structure of full length Cmr2 from Pyrococcus furiosus (Manganese bound form) | 分子名称: | CRISPR system Cmr subunit Cmr2, MANGANESE (II) ION, ZINC ION | 著者 | Benda, C, Ebert, J, Baumgaertner, M, Conti, E. | 登録日 | 2014-08-26 | 公開日 | 2014-10-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4. Mol.Cell, 56, 2014
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7MDM
| Structure of human p97 ATPase L464P mutant | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. | 登録日 | 2021-04-05 | 公開日 | 2021-08-25 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.86 Å) | 主引用文献 | Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity. Biochem.J., 478, 2021
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6E1X
| Crystal structure of product-bound complex of spermidine/spermine N-acetyltransferase SpeG | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Filippova, E.V, Minasov, G, Kiryukhina, O, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-07-10 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal structure of product-bound complex of spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae. To Be Published
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7MDZ
| 80S rabbit ribosome stalled with benzamide-CHX | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S21, ... | 著者 | Koga, Y, Hoang, E.M, Park, Y, Keszei, A.F.A, Murray, J, Shao, S, Liau, B.B. | 登録日 | 2021-04-06 | 公開日 | 2021-09-01 | 最終更新日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation. J.Am.Chem.Soc., 143, 2021
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1UPX
| The crystal structure of the Hybrid Cluster Protein from Desulfovibrio desulfuricans containing molecules in the oxidized and reduced states. | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FE4-S3 CLUSTER, HYDROXYLAMINE REDUCTASE, ... | 著者 | Aragao, D, Macedo, S, Mitchell, E.P, Lindley, P.F. | 登録日 | 2003-10-14 | 公開日 | 2003-12-02 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structure of the Hybrid Cluster Protein (Hcp) from Desulfovibrio Desulfuricans Atcc 27774 Containing Molecules in the Oxidized and Reduced States Acta Crystallogr.,Sect.D, 59, 2003
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5I1S
| Villin headpiece subdomain with a Lys30 to APC substitution | 分子名称: | D-Villin headpiece subdomain, Villin-1 | 著者 | Kreitler, D.F, Mortenson, D.E, Gellman, S.H, Forest, K.T. | 登録日 | 2016-02-05 | 公開日 | 2016-05-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization. J.Am.Chem.Soc., 138, 2016
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4WBH
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4NBY
| Crystal Structure of TcdA-A2 Bound to Two Molecules of A20.1 VHH | 分子名称: | A20.1 VHH, Cell wall-binding repeat protein | 著者 | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E, Klassen, J.S, Ng, K.K.S. | 登録日 | 2013-10-23 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. J.Biol.Chem., 289, 2014
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4WD0
| Crystal structure of HisAp form Arthrobacter aurescens | 分子名称: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | 著者 | MICHALSKA, K, VERDUZCO-CASTRO, E.A, ENDRES, M, BARONA-GOMEZ, F, JOACHIMIAK, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-09-05 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of HisAp form Arthrobacter aurescens To Be Published
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6DZW
| Cryo-EM structure of the ts2-inactive human serotonin transporter in complex with paroxetine and 15B8 Fab and 8B6 ScFv | 分子名称: | 15B8 antibody heavy chain, 15B8 antibody light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Coleman, J.A, Yang, D, Gouaux, E. | 登録日 | 2018-07-05 | 公開日 | 2019-04-24 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport. Nature, 569, 2019
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4NXJ
| Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum | 分子名称: | Bromodomain protein | 著者 | Wernimont, A.K, Loppnau, P, Knapp, S, Fonseca, M, Brennan, P.E, Dong, A, Walker, J.R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Hutchinson, A, Structural Genomics Consortium (SGC) | 登録日 | 2013-12-09 | 公開日 | 2014-03-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum TO BE PUBLISHED
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4NDV
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4NC1
| Crystal Structure of TcdA-A2 Bound to A20.1 VHH and A26.8 VHH | 分子名称: | A20.1 VHH, A26.8 VHH, Cell wall-binding repeat protein | 著者 | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | 登録日 | 2013-10-23 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. J.Biol.Chem., 289, 2014
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5I7Z
| Crystal structure of a Par-6 PDZ-Crumbs 3 C-terminal peptide complex | 分子名称: | Crb-3, DI(HYDROXYETHYL)ETHER, LD29223p | 著者 | Whitney, D.S, Peterson, F.C, Prehoda, K.E, Volkman, B.F. | 登録日 | 2016-02-18 | 公開日 | 2016-03-16 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Binding of Crumbs to the Par-6 CRIB-PDZ Module Is Regulated by Cdc42. Biochemistry, 55, 2016
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1V0R
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1V9C
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7MLU
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6E0L
| Structure of Rhodothermus marinus CdnE c-UMP-AMP synthase with Apcpp and Upnpp | 分子名称: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ... | 著者 | Eaglesham, J.B, Whiteley, A.T, de Oliveira Mann, C.C, Morehouse, B.R, Nieminen, E.A, King, D.S, Lee, A.S.Y, Mekalanos, J.J, Kranzusch, P.J. | 登録日 | 2018-07-06 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature, 567, 2019
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1V1K
| CDK2 IN COMPLEX WITH A DISUBSTITUTED 4, 6-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR | 分子名称: | (2R)-1-(DIMETHYLAMINO)-3-{4-[(6-{[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENOXY}PROPAN-2-OL, CELL DIVISION PROTEIN KINASE 2 | 著者 | Beattie, J.F, Breault, G.A, Ellston, R.P.A, Green, S, Jewsbury, P.J, Midgley, C.J, Naven, R.T, Minshull, C.A, Pauptit, R.A, Tucker, J.A, Pease, J.E. | 登録日 | 2004-04-16 | 公開日 | 2004-05-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines Bioorg.Med.Chem.Lett., 13, 2003
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4NKH
| Crystal structure of SspH1 LRR domain | 分子名称: | E3 ubiquitin-protein ligase sspH1 | 著者 | Keszei, A.F.A, Xiaojing, T, Mccormick, C, Zeqiraj, E, Rohde, J.R, Tyers, M, Sicheri, F. | 登録日 | 2013-11-12 | 公開日 | 2013-12-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase. Mol.Cell.Biol., 34, 2014
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6U9K
| MLL1 SET N3861I/Q3867L bound to inhibitor 18 (TC-5153) | 分子名称: | 5'-([(3S)-3-amino-3-carboxypropyl]{[1-(3,3-diphenylpropyl)azetidin-3-yl]methyl}amino)-5'-deoxyadenosine, GLYCEROL, Histone-lysine N-methyltransferase, ... | 著者 | Petrunak, E.M, Stuckey, J.A. | 登録日 | 2019-09-09 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of Potent Small-Molecule Inhibitors of MLL Methyltransferase. Acs Med.Chem.Lett., 11, 2020
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6UDJ
| HIV-1 bNAb 1-18 in complex with BG505 SOSIP.664 and 10-1074 | 分子名称: | 1-18 Fab Heavy Chain, 1-18 Fab Light Chain, 10-1074 Fab Heavy Chain, ... | 著者 | Abernathy, M.E, Barnes, C.O, Gristick, H.B, Bjorkman, P.J. | 登録日 | 2019-09-19 | 公開日 | 2020-01-29 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell, 180, 2020
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6UDK
| HIV-1 bNAb 1-55 in complex with modified BG505 SOSIP-based immunogen RC1 and 10-1074 | 分子名称: | 1-55 Fab Heavy Chain, 1-55 Fab Light Chain, 10-1074 Fab Heavy Chain, ... | 著者 | Abernathy, M.E, Barnes, C.O, Gristick, H.B, Bjorkman, P.J. | 登録日 | 2019-09-19 | 公開日 | 2020-01-29 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell, 180, 2020
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