6ONQ
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3H1J
| Stigmatellin-bound cytochrome bc1 complex from chicken | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, Coenzyme Q10, ... | 著者 | Zhang, Z, Huang, L, Shulmeister, V.M, Chi, Y.-I, Kim, K.K, Hung, L.-W, Crofts, A.R, Berry, E.A, Kim, S.-H. | 登録日 | 2009-04-12 | 公開日 | 2009-04-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Electron Transfer by Domain Movement in Cytochrome Bc1 Nature, 392, 1998
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5IG7
| Crystal structure of anti-gliadin 1002-1E01 Fab fragment in complex of peptide PLQPQQPFP | 分子名称: | 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, SULFATE ION, ... | 著者 | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | 登録日 | 2016-02-27 | 公開日 | 2017-03-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease. JCI Insight, 2, 2017
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6OVT
| Crystal Structure of IlvD from Mycobacterium tuberculosis | 分子名称: | DI(HYDROXYETHYL)ETHER, Dihydroxy-acid dehydratase, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Almo, S.C, Grove, T.L, Bonanno, J.B, Baker, E.N, Bashiri, G. | 登録日 | 2019-05-08 | 公開日 | 2019-08-07 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | The active site of theMycobacterium tuberculosisbranched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster. J.Biol.Chem., 294, 2019
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6U9W
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6QPG
| Influenza A virus Polymerase Heterotrimer A/nt/60/1968(H3N2) in complex with Nanobody NB8205 | 分子名称: | Nanobody NB8205, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Fan, H.T, Keown, J.R, Fodor, E, Grimes, J.M. | 登録日 | 2019-02-13 | 公開日 | 2019-09-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
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4W8Q
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8DXR
| Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 5 | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | 登録日 | 2022-08-02 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
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8DXP
| Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 3 | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | 登録日 | 2022-08-02 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
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8DXQ
| Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 4 | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | 登録日 | 2022-08-02 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
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8DXO
| Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 2 | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | 登録日 | 2022-08-02 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
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8DXN
| Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 1 | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | 登録日 | 2022-08-02 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
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6OBF
| JAK2 JH2 in complex with JAK179 | 分子名称: | GLYCEROL, Tyrosine-protein kinase JAK2, [4-({5-amino-3-[(4-sulfamoylphenyl)amino]-1H-1,2,4-triazole-1-carbonyl}amino)phenoxy]acetic acid | 著者 | Krimmer, S.G, Liosi, M.E, Schlessinger, J, Jorgensen, W.L. | 登録日 | 2019-03-20 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Selective Janus Kinase 2 (JAK2) Pseudokinase Ligands with a Diaminotriazole Core. J.Med.Chem., 63, 2020
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6OG7
| 70S termination complex with RF2 bound to the UGA codon. Non-rotated ribosome with RF2 bound (Structure II) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | 登録日 | 2019-04-01 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
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6UIR
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6TZF
| ADC-7 in complex with boronic acid transition state inhibitor S17079 | 分子名称: | 3-(1-{[hydroxy(phosphonooxy)boranyl]methyl}-1H-1,2,3-triazol-4-yl)benzoic acid, Beta-lactamase | 著者 | Fish, E.R, Powers, R.A, Wallar, B.J. | 登録日 | 2019-08-12 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | 1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of beta-Lactamase Inhibitors againstAcinetobacter baumanniiCephalosporinase. Acs Infect Dis., 6, 2020
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8DMH
| Lymphocytic choriomeningitis virus glycoprotein in complex with neutralizing antibody M28 | 分子名称: | 18.5C-M28 Fab Heavy Chain, 18.5C-M28 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Moon-Walker, A, Hastie, K.M, Zyla, D.S, Saphire, E.O. | 登録日 | 2022-07-08 | 公開日 | 2023-04-12 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus. Cell Chem Biol, 30, 2023
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5L9A
| L-threonine dehydrogenase from trypanosoma brucei. | 分子名称: | ACETATE ION, L-threonine 3-dehydrogenase | 著者 | Erskine, P.T, Cooper, J.B, Adjogatse, E, Kelly, J, Wood, S.P. | 登録日 | 2016-06-09 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
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5I73
| X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central and allosteric sites | 分子名称: | (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-AMINOHEXANOIC ACID, ... | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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6ULE
| Crystal structure of 2541 Fab in complex with circumsporozoite protein NANP5 | 分子名称: | 2541 Antibody, heavy chain, light chain, ... | 著者 | Thai, E, Scally, S.W, Murugan, R, Wardemann, H, Julien, J.P. | 登録日 | 2019-10-07 | 公開日 | 2020-06-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. Nat. Med., 26, 2020
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5LA6
| Tubulin-pironetin complex | 分子名称: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Prota, A.E, Setter, J, Waight, A.B, Bargsten, K, Murga, J, Diaz, J.F, Steinmetz, M.O. | 登録日 | 2016-06-13 | 公開日 | 2016-07-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Pironetin Binds Covalently to alpha Cys316 and Perturbs a Major Loop and Helix of alpha-Tubulin to Inhibit Microtubule Formation. J.Mol.Biol., 428, 2016
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6OS9
| human Neurotensin Receptor 1 (hNTSR1) - Gi1 Protein Complex in canonical conformation (C state) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Kato, H.E, Zhang, Y, Kobilka, B.K, Skiniotis, G. | 登録日 | 2019-05-01 | 公開日 | 2019-07-10 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Conformational transitions of a neurotensin receptor 1-Gi1complex. Nature, 572, 2019
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6EF8
| Cryo-EM of the OmcS nanowires from Geobacter sulfurreducens | 分子名称: | C-type cytochrome OmcS, HEME C | 著者 | Wang, F, Gu, Y, Egelman, E.H, Malvankar, N.S. | 登録日 | 2018-08-16 | 公開日 | 2019-04-10 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of Microbial Nanowires Reveals Stacked Hemes that Transport Electrons over Micrometers. Cell, 177, 2019
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6OTV
| Crystal structure of putative isomerase EC2056 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, PHOSPHATE ION, ... | 著者 | Chang, C, Evdokimova, E, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-05-03 | 公開日 | 2019-05-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of putative isomerase EC2056 To Be Published
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6OAC
| PQR530 [(S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine] bound to the PI3Ka catalytic subunit p110alpha | 分子名称: | 4-(difluoromethyl)-5-{4-[(3S)-3-methylmorpholin-4-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}pyridin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Burke, J.E, McPhail, J.A. | 登録日 | 2019-03-15 | 公開日 | 2019-06-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | (S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase. J.Med.Chem., 62, 2019
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