8DXR

Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 5

Summary for 8DXR

• Entry DOI: 10.2210/pdb8dxr/pdb
• Related: 8DXN 8DXO 8DXP 8DXQ
• EMDB information: 27774
• Descriptor: Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A (1 entity in total)
• Functional Keywords: lrrc8c, lrrc8a, swell, vrac, chimera, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 663233.86

Authors

Takahashi, H.,Yamada, T.,Denton, J.S.,Strange, K.,Karakas, E. (deposition date: 2022-08-02, release date: 2023-03-22)

• Primary citation: Takahashi, H.,Yamada, T.,Denton, J.S.,Strange, K.,Karakas, E.; Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly.; Elife, 12:-, 2023; PubMed: 36897307; DOI: 10.7554/eLife.82431

Experimental method

ELECTRON MICROSCOPY (4 Å)