Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 40736 件

7Q6A
DownloadVisualize
BU of 7q6a by Molmil
Crystal structure of Chaetomium thermophilum C30S Ahp1 in post-reaction state
分子名称: GLYCEROL, SULFATE ION, Thioredoxin domain-containing protein
著者Ravichandran, K.E, Wilk, P, Grudnik, P, Glatt, S.
登録日2021-11-05
公開日2022-08-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation.
Embo J., 41, 2022
8F1V
DownloadVisualize
BU of 8f1v by Molmil
A benzimidazole (DB1476) sequence-specific recognition of 5'-CGCAAAAAAGCG-3' in B-orientation
分子名称: 4,4'-(1H-benzimidazole-2,6-diyl)di(benzene-1-carboximidamide), DNA (5'-D(*CP*GP*CP*AP*AP*AP*AP*AP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*TP*TP*TP*TP*TP*GP*CP*G)-3'), ...
著者Ogbonna, E.N, Wilson, W.D.
登録日2022-11-06
公開日2023-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.
Acs Bio Med Chem Au, 3, 2023
8F2Y
DownloadVisualize
BU of 8f2y by Molmil
Structure of an alternating AT dodecamer: 5'-CGCGATATCGCG-3
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*TP*AP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
著者Ogbonna, E.N, Wilson, W.D.
登録日2022-11-09
公開日2023-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.
Acs Bio Med Chem Au, 3, 2023
6V3E
DownloadVisualize
BU of 6v3e by Molmil
Cryo-EM structure of the Acinetobacter baumannii Ribosome: 30S subunit
分子名称: 16s Ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Morgan, C.E, Yu, E.W.
登録日2019-11-25
公開日2020-02-05
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development.
Mbio, 11, 2020
8SUF
DownloadVisualize
BU of 8suf by Molmil
The complex of TOL-1 ectodomain bound to LAT-1 Lectin domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Latrophilin-like protein 1, ...
著者Carmona Rosas, G, Li, J, Arac, D, Ozkan, E.
登録日2023-05-12
公開日2024-05-15
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural basis and functional roles for Toll-like receptor binding to Latrophilin adhesion-GPCR in embryo development
To Be Published
6XCP
DownloadVisualize
BU of 6xcp by Molmil
Immune receptor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hybrid insulin peptide, ...
著者Tran, T.M, Faridi, P, Lim, J.J, Ting, T.Y, Onwukwe, G, Bhattacharjee, P, Jones, M.C, Tresoldi, E, Cameron, J.F, La-Gruta, L.N, Purcell, W.A, Mannering, I.S, Rossjohn, J, Reid, H.H.
登録日2020-06-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.
Nat Commun, 12, 2021
6N0J
DownloadVisualize
BU of 6n0j by Molmil
The complex of CCG-222740 bound to pirin
分子名称: (3S)-N-(4-chlorophenyl)-5,5-difluoro-1-[3-(furan-2-yl)benzene-1-carbonyl]piperidine-3-carboxamide, 1,2-ETHANEDIOL, FE (III) ION, ...
著者Lisabeth, E.M, Jin, X, Neubig, R.
登録日2018-11-07
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Antifibrotic and Antimetastatic Compounds
ACS Pharmacol Transl Sci, 2, 2019
7PJR
DownloadVisualize
BU of 7pjr by Molmil
Notum_ARUK3000438
分子名称: 1-[4-chloranyl-3-(trifluoromethyl)phenyl]-1,2,3-triazole, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ...
著者Vecchia, L, Zhao, Y, Fish, P, Jones, E.Y.
登録日2021-08-24
公開日2022-09-07
最終更新日2023-03-22
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.
J.Med.Chem., 65, 2022
7NGU
DownloadVisualize
BU of 7ngu by Molmil
Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
分子名称: HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-(4-methoxyphenyl)-4-methyl-piperidine-1-carboxamide
著者Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
登録日2021-02-09
公開日2022-02-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization
To Be Published
6EXN
DownloadVisualize
BU of 6exn by Molmil
Post-catalytic P complex spliceosome with 3' splice site docked
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ...
著者Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K.
登録日2017-11-08
公開日2018-01-17
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
6ESM
DownloadVisualize
BU of 6esm by Molmil
Crystal structure of MMP9 in complex with inhibitor BE4.
分子名称: (2~{S})-2-[2-[4-(4-methoxyphenyl)phenyl]sulfanylphenyl]pentanedioic acid, CALCIUM ION, Matrix metalloproteinase-9,Matrix metalloproteinase-9, ...
著者Ciccone, L, Tepshi, L, Nuti, E, Rossello, A, Stura, E.A.
登録日2017-10-23
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.104 Å)
主引用文献Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies.
J. Med. Chem., 61, 2018
8CDQ
DownloadVisualize
BU of 8cdq by Molmil
Plasmodium falciparum Myosin A full-length, post-rigor state complexed to the inhibitor KNX-002 and Mg.ATP-gamma-S
分子名称: 1,2-ETHANEDIOL, 1-(4-methoxyphenyl)-~{N}-[(3-thiophen-2-yl-1~{H}-pyrazol-4-yl)methyl]cyclopropan-1-amine, GLYCEROL, ...
著者Moussaoui, D, Robblee, J.P, Robert-Paganin, J, Auguin, D, Fisher, F, Fagnant, P.M, MacFarlane, J.E, Schaletzky, J, Wehri, E, Mueller-Dieckmann, C, Baum, J, Trybus, K.M, Houdusse, A.
登録日2023-01-31
公開日2023-06-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Mechanism of small molecule inhibition of Plasmodium falciparum myosin A informs antimalarial drug design.
Nat Commun, 14, 2023
6S4O
DownloadVisualize
BU of 6s4o by Molmil
The crystal structure of glycogen phosphorylase in complex with 9
分子名称: (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-naphthalen-2-yl-1~{H}-imidazol-4-yl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ...
著者Kyriakis, E, Solovou, T.G.A, Papaioannou, O.S.E, Skamnaki, V.T, Leonidas, D.D.
登録日2019-06-28
公開日2020-02-19
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The architecture of hydrogen and sulfur sigma-hole interactions explain differences in the inhibitory potency of C-beta-d-glucopyranosyl thiazoles, imidazoles and an N-beta-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design.
Bioorg.Med.Chem., 28, 2020
7NGW
DownloadVisualize
BU of 7ngw by Molmil
Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
分子名称: HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-(4-hydroxyphenyl)-4-methyl-piperidine-1-carboxamide
著者Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
登録日2021-02-09
公開日2022-02-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization
To Be Published
7Q68
DownloadVisualize
BU of 7q68 by Molmil
Crystal structure of Chaetomium thermophilum wild-type Ahp1
分子名称: GLYCEROL, SULFATE ION, Thioredoxin domain-containing protein
著者Ravichandran, K.E, Wilk, P, Grudnik, P, Glatt, S.
登録日2021-11-05
公開日2022-08-31
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation.
Embo J., 41, 2022
6XMV
DownloadVisualize
BU of 6xmv by Molmil
The crystal structure of Neisseria gonorrhoeae DolP (NGO1985)
分子名称: CHLORIDE ION, Hemolysin,Endolysin
著者Li, J, Peterson Brown, L.E, Reed, R.W, Wierzbicki, I.H, Sikora, A.E, Korotkov, K.V.
登録日2020-06-30
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The structure and function of a new component of Bam complex in Neisseria
To Be Published
5MG0
DownloadVisualize
BU of 5mg0 by Molmil
Structure of PAS-GAF fragment of Deinococcus phytochrome by serial femtosecond crystallography
分子名称: 1,2-ETHANEDIOL, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome, ...
著者Burgie, E.S, Fuller, F.D, Gul, S, Miller, M.D, Young, I.D, Brewster, A.S, Clinger, J, Aller, P, Braeuer, P, Hutchison, C, Alonso-Mori, R, Kern, J, Yachandra, V.K, Yano, J, Sauter, N.K, Phillips Jr, G.N, Vierstra, R.D, Orville, A.M.
登録日2016-11-20
公開日2017-02-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers.
Nat. Methods, 14, 2017
7ZA3
DownloadVisualize
BU of 7za3 by Molmil
GPC3-Unc5D octamer structure and role in cell migration
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ...
著者Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E.
登録日2022-03-21
公開日2022-11-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献GPC3-Unc5 receptor complex structure and role in cell migration.
Cell, 185, 2022
7PK3
DownloadVisualize
BU of 7pk3 by Molmil
Notum_ARUK3001185
分子名称: 1-[2,4-bis(chloranyl)-3-(trifluoromethyl)phenyl]-1,2,3-triazole, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ...
著者Vecchia, L, Hillier, J, Zhao, Y, Fish, P, Jones, E.Y.
登録日2021-08-25
公開日2022-09-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.
J.Med.Chem., 65, 2022
7ZA2
DownloadVisualize
BU of 7za2 by Molmil
GPC3-Unc5D octamer structure and role in cell migration
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ...
著者Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E.
登録日2022-03-21
公開日2022-11-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献GPC3-Unc5 receptor complex structure and role in cell migration.
Cell, 185, 2022
7PKV
DownloadVisualize
BU of 7pkv by Molmil
Notum_Inhibitor ARUK3000223
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, Palmitoleoyl-protein carboxylesterase NOTUM, ...
著者Ruza, R, Zhao, Y, Fish, P, Jones, E.Y.
登録日2021-08-26
公開日2022-09-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.
J.Med.Chem., 65, 2022
6MYY
DownloadVisualize
BU of 6myy by Molmil
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ...
著者Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D.
登録日2018-11-02
公開日2018-11-14
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
6UWT
DownloadVisualize
BU of 6uwt by Molmil
Clostridium difficile binary toxin translocase CDTb tetradecamer in symmetric conformation
分子名称: ADP-ribosyltransferase binding component, CALCIUM ION
著者Xu, X, Pozharski, E, des Georges, A.
登録日2019-11-05
公開日2020-01-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly.
Proc.Natl.Acad.Sci.USA, 117, 2020
7APE
DownloadVisualize
BU of 7ape by Molmil
Crystal structure of LpqY from Mycobacterium thermoresistible in complex with trehalose
分子名称: Lipoprotein (Sugar-binding) lpqY, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose
著者Furze, C.M, Guy, C.M, Angula, J, Cameron, A.D, Fullam, E.
登録日2020-10-16
公開日2021-04-28
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter.
J.Biol.Chem., 296, 2021
5MLU
DownloadVisualize
BU of 5mlu by Molmil
Crystal structure of the PFV GAG CBS bound to a mononucleosome
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B, ...
著者Pye, V.E, Maskell, D.P, Lesbats, P, Cherepanov, P.
登録日2016-12-07
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for spumavirus GAG tethering to chromatin.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

223166

件を2024-07-31に公開中

PDB statisticsPDBj update infoContact PDBjnumon