6G9O
 
 | | Structure of full-length homomeric mLRRC8A volume-regulated anion channel at 4.25 A resolution | | Descriptor: | Volume-regulated anion channel subunit LRRC8A | | Authors: | Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R. | | Deposit date: | 2018-04-11 | | Release date: | 2018-05-16 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4.25 Å) | | Cite: | Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
|
|
6G8Z
 | | Structure of the pore domain of homomeric mLRRC8A volume-regulated anion channel at 3.66 A resolution | | Descriptor: | Volume-regulated anion channel subunit LRRC8A | | Authors: | Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R. | | Deposit date: | 2018-04-10 | | Release date: | 2018-05-16 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
|
|
6G9L
 | | Structure of homomeric mLRRC8A volume-regulated anion channel at 5.01 A resolution | | Descriptor: | Volume-regulated anion channel subunit LRRC8A | | Authors: | Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R. | | Deposit date: | 2018-04-11 | | Release date: | 2018-05-16 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (5.01 Å) | | Cite: | Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
|
|
8BEN
 | | LRR domain Structure of the LRRC8C protein | | Descriptor: | Volume-regulated anion channel subunit LRRC8C | | Authors: | Sawicka, M, Dutzler, R. | | Deposit date: | 2022-10-21 | | Release date: | 2022-12-14 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of a volume-regulated heteromeric LRRC8A/C channel.
Nat.Struct.Mol.Biol., 30, 2023
|
|
2J9L
 | | Cytoplasmic Domain of the Human Chloride Transporter ClC-5 in complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE CHANNEL PROTEIN 5, CHLORIDE ION | | Authors: | Meyer, S, Savaresi, S, Forster, I.C, Dutzler, R. | | Deposit date: | 2006-11-13 | | Release date: | 2007-01-04 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Nucleotide Recognition by the Cytoplasmic Domain of the Human Chloride Transporter Clc-5
Nat.Struct.Mol.Biol., 14, 2006
|
|
7P14
 | | Structure of full-length rXKR9 in complex with a sybody at 3.66A | | Descriptor: | DIUNDECYL PHOSPHATIDYL CHOLINE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, Sybody, ... | | Authors: | Straub, M.S, Sawicka, M, Dutzler, R. | | Deposit date: | 2021-07-01 | | Release date: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Cryo-EM structures of the caspase activated protein XKR9 involved in apoptotic lipid scrambling.
Elife, 10, 2021
|
|
6YTV
 | |
2JA3
 | | Cytoplasmic Domain of the Human Chloride Transporter ClC-5 in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE CHANNEL PROTEIN 5 | | Authors: | Meyer, S, Savaresi, S, Forster, I.C, Dutzler, R. | | Deposit date: | 2006-11-21 | | Release date: | 2007-01-04 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Nucleotide Recognition by the Cytoplasmic Domain of the Human Chloride Transporter Clc-5
Nat.Struct.Mol.Biol., 14, 2006
|
|
6YTX
 | |
5NL2
 | | cryo-EM structure of the mTMEM16A ion channel at 6.6 A resolution. | | Descriptor: | Anoctamin-1 | | Authors: | Paulino, C, Neldner, Y, Lam, K.M, Kalienkova, V, Brunner, J.D, Schenck, S, Dutzler, R. | | Deposit date: | 2017-04-03 | | Release date: | 2017-06-07 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A.
Elife, 6, 2017
|
|
2HT3
 | | Structure of the Escherichia coli ClC chloride channel Y445L mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-25 | | Release date: | 2006-09-19 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
|
|
2HT4
 | | Structure of the Escherichia coli ClC chloride channel Y445W mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-25 | | Release date: | 2006-09-19 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
|
|
2HTL
 | | Structure of the Escherichia coli ClC chloride channel Y445F mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-19 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
|
|
2HTK
 | | Structure of the Escherichia coli ClC chloride channel Y445A mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.41 Å) | | Cite: | Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
|
|
7ZK3
 | | Structure of 1PBC- and calcium-bound mTMEM16A(ac) chloride channel at 2.85 A resolution | | Descriptor: | 1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile, Anoctamin-1, CALCIUM ION | | Authors: | Lam, A.K.M, Rutz, S, Dutzler, R. | | Deposit date: | 2022-04-12 | | Release date: | 2022-05-25 | | Last modified: | 2022-06-01 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC.
Nat Commun, 13, 2022
|
|
5M8K
 | | Crystal structure of Eremococcus coleocola manganese transporter mutant E129Q | | Descriptor: | Divalent metal cation transporter MntH | | Authors: | Manatschal, C, Ehrnstorfer, I.A, Arnold, F.M, Laederach, J, Dutzler, R. | | Deposit date: | 2016-10-29 | | Release date: | 2017-01-11 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family.
Nat Commun, 8, 2017
|
|
5M8A
 | | Crystal structure of Eremococcus coleocola manganese transporter mutant E129A | | Descriptor: | Divalent metal cation transporter MntH | | Authors: | Manatschal, C, Ehrnstorfer, I.A, Arnold, F.M, Laederach, J, Dutzler, R. | | Deposit date: | 2016-10-28 | | Release date: | 2017-01-11 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family.
Nat Commun, 8, 2017
|
|
5M87
 | | Crystal structure of Eremococcus coleocola manganese transporter | | Descriptor: | DECYL-BETA-D-MALTOPYRANOSIDE, Divalent metal cation transporter MntH | | Authors: | Manatschal, C, Ehrnstorfer, I.A, Arnold, F.M, Laederach, J, Dutzler, R. | | Deposit date: | 2016-10-28 | | Release date: | 2017-01-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family.
Nat Commun, 8, 2017
|
|
8B8G
 | | Cryo-EM structure of Ca2+-free mTMEM16F F518H mutant in Digitonin | | Descriptor: | Anoctamin-6 | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-16 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8B8K
 | | Cryo-EM structure of Ca2+-bound mTMEM16F N562A mutant in Digitonin closed/closed | | Descriptor: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-6, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-16 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8B8J
 | | Cryo-EM structure of Ca2+-bound mTMEM16F F518H mutant in Digitonin | | Descriptor: | Anoctamin-6, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-16 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8BC0
 | | Cryo-EM structure of Ca2+-bound mTMEM16F F518A Q623A mutant in GDN open/closed | | Descriptor: | Anoctamin-6, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-14 | | Release date: | 2022-11-16 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8BC1
 | | Cryo-EM Structure of Ca2+-bound mTMEM16F F518A_Q623A mutant in GDN | | Descriptor: | Anoctamin-6,mTMEM16F, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-14 | | Release date: | 2022-11-16 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8B8M
 | | Cryo-EM structure of Ca2+-bound mTMEM16F N562A mutant in Digitonin open/closed | | Descriptor: | Anoctamin-6, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-16 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
|
|
8B40
 | |
