6RTC
 
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6YTO
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6YTQ
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6YTK
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6YTL
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8BEN
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8B8K
 | | Cryo-EM structure of Ca2+-bound mTMEM16F N562A mutant in Digitonin closed/closed | | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-6, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8B8G
 | | Cryo-EM structure of Ca2+-free mTMEM16F F518H mutant in Digitonin | | 分子名称: | Anoctamin-6 | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8B8J
 | | Cryo-EM structure of Ca2+-bound mTMEM16F F518H mutant in Digitonin | | 分子名称: | Anoctamin-6, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8BC0
 | | Cryo-EM structure of Ca2+-bound mTMEM16F F518A Q623A mutant in GDN open/closed | | 分子名称: | Anoctamin-6, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-14 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8BC1
 | | Cryo-EM Structure of Ca2+-bound mTMEM16F F518A_Q623A mutant in GDN | | 分子名称: | Anoctamin-6,mTMEM16F, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-14 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8B8M
 | | Cryo-EM structure of Ca2+-bound mTMEM16F N562A mutant in Digitonin open/closed | | 分子名称: | Anoctamin-6, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8B40
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8B41
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8B8Q
 | | Structure of mTMEM16F in lipid Nanodiscs in the presence of Ca2+ | | 分子名称: | Anoctamin-6, CALCIUM ION | | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8B42
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2XQ4
 | | Pentameric ligand gated ion channel GLIC in complex with tetramethylarsonium (TMAs) | | 分子名称: | ARSENIC, GLR4197 PROTEIN | | 著者 | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | | 登録日 | 2010-09-01 | | 公開日 | 2010-11-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
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8C03
 | | Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy12 in outward-facing conformation | | 分子名称: | 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, Solute carrier family 40 member 1 | | 著者 | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | 登録日 | 2022-12-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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2XQ6
 | | Pentameric ligand gated ion channel GLIC in complex with cesium ion (Cs+) | | 分子名称: | CESIUM ION, GLR4197 PROTEIN | | 著者 | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | | 登録日 | 2010-09-01 | | 公開日 | 2010-11-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
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8BZY
 | | Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy3 in occluded conformation | | 分子名称: | 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, DIUNDECYL PHOSPHATIDYL CHOLINE, Solute carrier family 40 member 1, ... | | 著者 | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | 登録日 | 2022-12-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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2XQA
 | | Pentameric ligand gated ion channel GLIC in complex with tetrabutylantimony (TBSb) | | 分子名称: | ANTIMONY (III) ION, GLR4197 PROTEIN | | 著者 | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | | 登録日 | 2010-09-01 | | 公開日 | 2010-11-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
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8C02
 | | Structure of SLC40/ferroportin in complex with synthetic nanobody Sy3 in occluded conformation | | 分子名称: | Solute carrier family 40 member 1, Sybody3 | | 著者 | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | 登録日 | 2022-12-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | | 主引用文献 | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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2XQ9
 | | Pentameric ligand gated ion channel GLIC mutant E221A in complex with tetraethylarsonium (TEAs) | | 分子名称: | ARSENIC, GLR4197 PROTEIN | | 著者 | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | | 登録日 | 2010-09-01 | | 公開日 | 2010-11-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
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2XQ8
 | | Pentameric ligand gated ion channel GLIC in complex with zinc ion (Zn2+) | | 分子名称: | GLR4197 PROTEIN, ZINC ION | | 著者 | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | | 登録日 | 2010-09-01 | | 公開日 | 2010-11-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
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2XQ7
 | | Pentameric ligand gated ion channel GLIC in complex with cadmium ion (Cd2+) | | 分子名称: | CADMIUM ION, GLR4197 PROTEIN | | 著者 | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | | 登録日 | 2010-09-01 | | 公開日 | 2010-11-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
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