3TS3
 
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4E5E
 | | Crystal structure of avian influenza virus PAn Apo | | Descriptor: | MANGANESE (II) ION, Polymerase protein PA, SULFATE ION | | Authors: | DuBois, R.M, White, S.W. | | Deposit date: | 2012-03-14 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.048 Å) | | Cite: | Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
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4E5G
 | | Crystal structure of avian influenza virus PAn bound to compound 2 | | Descriptor: | 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, Polymerase protein PA, ... | | Authors: | DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W. | | Deposit date: | 2012-03-14 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.647 Å) | | Cite: | Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
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4E5F
 | | Crystal structure of avian influenza virus PAn bound to compound 1 | | Descriptor: | 2-hydroxyisoquinoline-1,3(2H,4H)-dione, MANGANESE (II) ION, Polymerase protein PA, ... | | Authors: | DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W. | | Deposit date: | 2012-03-14 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.392 Å) | | Cite: | Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
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4E5H
 | | Crystal structure of avian influenza virus PAn bound to compound 3 | | Descriptor: | (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, Polymerase protein PA, ... | | Authors: | DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W. | | Deposit date: | 2012-03-14 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.158 Å) | | Cite: | Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
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4E5L
 | | Crystal structure of avian influenza virus PAn bound to compound 6 | | Descriptor: | 2,3-DIHYDROXY-BENZOIC ACID, MANGANESE (II) ION, Polymerase protein PA, ... | | Authors: | DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W. | | Deposit date: | 2012-03-14 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.469 Å) | | Cite: | Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
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4ADG
 | | Crystal structure of the Rubella virus envelope Glycoprotein E1 in post-fusion form (crystal form II) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | Authors: | DuBois, R.M, Vaney, M.C, Tortorici, M.A, Al Kurdi, R, Barba-Spaeth, G, Rey, F.A. | | Deposit date: | 2011-12-26 | | Release date: | 2013-01-09 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1.
Nature, 493, 2013
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4ADI
 | | Crystal structure of the Rubella virus envelope glycoprotein E1 in post-fusion form (crystal form I) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | Authors: | DuBois, R.M, Vaney, M.C, Tortorici, M.A, Al Kurdi, R, Barba-Spaeth, G, Rey, F.A. | | Deposit date: | 2011-12-26 | | Release date: | 2013-01-09 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1.
Nature, 493, 2013
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4ADJ
 | | Crystal structure of the Rubella virus glycoprotein E1 in its post-fusion form crystallized in presence of 1mM of calcium acetate | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | | Authors: | DuBois, R.M, Vaney, M.C, Tortorici, M.A, Al Kurdi, R, Barba-Spaeth, G, Rey, F.A. | | Deposit date: | 2011-12-26 | | Release date: | 2013-01-09 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1.
Nature, 493, 2013
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3MLH
 | | Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain | | Descriptor: | GLYCEROL, Hemagglutinin | | Authors: | DuBois, R.M, Aguilar-Yanez, J.M, Mendoza-Ochoa, G.I, Schultz-Cherry, S, Alvarez, M.M, White, S.W, Russell, C.J. | | Deposit date: | 2010-04-16 | | Release date: | 2010-12-01 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | The Receptor-Binding Domain of Influenza Virus Hemagglutinin Produced in Escherichia coli Folds into Its Native, Immunogenic Structure.
J.Virol., 85, 2011
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4JUL
 | | Crystal structure of H5N1 influenza virus hemagglutinin, clade 2.3.4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | DuBois, R.M, Zaraket, H, Reddivari, M, Coop, T, Heath, R.J, White, S.W, Russell, C.J. | | Deposit date: | 2013-03-25 | | Release date: | 2014-05-07 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.7927 Å) | | Cite: | To be published
To be Published
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4JUK
 | | Crystal structure of H5N1 influenza virus hemagglutinin, clade 2.3.2.1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... | | Authors: | DuBois, R.M, Zaraket, H, Reddivari, M, Coop, T, Heath, R.J, White, S.W, Russell, C.J. | | Deposit date: | 2013-03-25 | | Release date: | 2014-05-07 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.7502 Å) | | Cite: | To be published
To be Published
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4JUN
 | | Crystal structure of H5N1 influenza virus hemagglutinin, clade 5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | DuBois, R.M, Zaraket, H, Reddivari, M, Coop, T, Heath, R.J, White, S.W, Russell, C.J. | | Deposit date: | 2013-03-25 | | Release date: | 2014-05-07 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.3398 Å) | | Cite: | To be published
To be Published
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4JUM
 | | Crystal structure of H5N1 influenza virus hemagglutinin, clade 4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | DuBois, R.M, Zaraket, H, Reddivari, M, Coop, T, Heath, R.J, White, S.W, Russell, C.J. | | Deposit date: | 2013-03-25 | | Release date: | 2014-05-07 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.997 Å) | | Cite: | To be published
To be Published
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3S13
 | | Crystal structure of H5N1 influenza virus hemagglutinin, strain YU562 crystal form 2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | | Authors: | DuBois, R.M, Zaraket, H, Reddivari, M, Heath, R.J, White, S.W, Russell, C.J. | | Deposit date: | 2011-05-14 | | Release date: | 2011-12-14 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.96 Å) | | Cite: | Acid stability of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity.
Plos Pathog., 7, 2011
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3S12
 | | Crystal structure of H5N1 influenza virus hemagglutinin, strain YU562 crystal form 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | | Authors: | DuBois, R.M, Zaraket, H, Reddivari, M, Heath, R.J, White, S.W, Russell, C.J. | | Deposit date: | 2011-05-14 | | Release date: | 2011-12-14 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Acid stability of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity.
Plos Pathog., 7, 2011
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3S11
 | | Crystal structure of H5N1 influenza virus hemagglutinin, strain 437-10 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | Authors: | DuBois, R.M, Zaraket, H, Reddivari, M, Heath, R.J, White, S.W, Russell, C.J. | | Deposit date: | 2011-05-14 | | Release date: | 2011-12-14 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Acid stability of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity.
Plos Pathog., 7, 2011
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4E5I
 | | Crystal structure of avian influenza virus PAn bound to compound 4 | | Descriptor: | 5-hydroxy-2-(1-methyl-1H-imidazol-4-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid, MANGANESE (II) ION, Polymerase protein PA, ... | | Authors: | DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W. | | Deposit date: | 2012-03-14 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.944 Å) | | Cite: | Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
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4E5J
 | | Crystal structure of avian influenza virus PAn bound to compound 5 | | Descriptor: | 2-[3-(acetylamino)phenyl]-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid, MANGANESE (II) ION, Polymerase protein PA, ... | | Authors: | DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W. | | Deposit date: | 2012-03-14 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
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7T8W
 | | Structure of antibody 3G12 bound to Respiratory Syncytial Virus G central conserved domain mutant S177Q | | Descriptor: | 3G12 Fab Heavy chain, 3G12 Fab Light chain, Mature secreted glycoprotein G | | Authors: | Nunez Castrejon, A.M, O'Rourke, S.M, Kauvar, L.M, DuBois, R.M. | | Deposit date: | 2021-12-17 | | Release date: | 2022-02-09 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure-Based Design and Antigenic Validation of Respiratory Syncytial Virus G Immunogens.
J.Virol., 96, 2022
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5I30
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9CP0
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8TN8
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8TUI
 | | Crystal structure of Fab-Lirilumab bound to KIR2DL3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell immunoglobulin-like receptor 2DL3, Lirilumab Fab Heavy Chain, ... | | Authors: | Lorig-Roach, N, DuBois, R.M. | | Deposit date: | 2023-08-16 | | Release date: | 2023-12-06 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab.
Sci Rep, 14, 2024
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6UVO
 | | Structure of antibody 3G12 bound to the central conserved domain of RSV G | | Descriptor: | 3G12 Fab Heavy chain, 3G12 Fab light chain, Major surface glycoprotein G | | Authors: | Fedechkin, S.O, George, N.L, Nunez Castrejon, A.M, Dillen, J, Kauvar, L.M, DuBois, R.M. | | Deposit date: | 2019-11-03 | | Release date: | 2019-12-18 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Conformational Flexibility in Respiratory Syncytial Virus G Neutralizing Epitopes.
J.Virol., 94, 2020
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