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PDB: 57 件

6N29
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Crystal structure of monomeric von Willebrand Factor D`D3 assembly
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Dong, X, Arndt, J.W, Springer, T.A.
登録日2018-11-12
公開日2019-01-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.
Blood, 133, 2019
5Z2T
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Crystal structure of DNA-bound DUX4-HD2
分子名称: 5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*TP*T)-3', 5'-D(P*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3', Double homeobox protein 4
著者Dong, X, Zhang, W, Wu, H, Huang, J, Zhang, M, Wang, P, Zhang, H, Chen, Z, Chen, S, Meng, G.
登録日2018-01-04
公開日2018-04-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.623 Å)
主引用文献Structural basis of DUX4/IGH-driven transactivation.
Leukemia, 32, 2018
6A8R
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Crystal structure of DUX4 HD2 domain associated with ERG DNA binding site
分子名称: DNA (5'-D(P*AP*AP*TP*CP*TP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*TP*GP*AP*GP*AP*TP*T)-3'), Double homeobox protein 4
著者Dong, X, Zhang, H, Cheng, N, Meng, G.
登録日2018-07-10
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献DUX4HD2-DNAERGstructure reveals new insight into DUX4-Responsive-Element.
Leukemia, 33, 2019
7TAC
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Cryo-EM structure of the (TGA3)2-(NPR1)2-(TGA3)2 complex
分子名称: PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ...
著者Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P.
登録日2021-12-20
公開日2022-03-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of NPR1 in activating plant immunity.
Nature, 605, 2022
7TAD
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CryoEM structure of the (NPR1)2-(TGA3)2 complex
分子名称: PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ...
著者Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P.
登録日2021-12-20
公開日2022-03-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of NPR1 in activating plant immunity.
Nature, 605, 2022
5VBT
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Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor
分子名称: UBH04
著者DONG, A, DONG, X, LIU, L, GUO, Y, LI, Y, ZHANG, W, WALKER, J.R, SIDHU, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC)
登録日2017-03-30
公開日2017-06-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor
to be published
6WPG
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Structural Basis of Salicylic Acid Perception by Arabidopsis NPR Proteins
分子名称: 2-HYDROXYBENZOIC ACID, Regulatory protein NPR4
著者Wang, W, Withers, J, Li, H, Zwack, P.J, Rusnac, D.V, Shi, H, Liu, L, Yan, S, Hinds, T.R, Guttman, M, Dong, X, Zheng, N.
登録日2020-04-27
公開日2020-08-12
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.283 Å)
主引用文献Structural basis of salicylic acid perception by Arabidopsis NPR proteins.
Nature, 586, 2020
4C29
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Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation
分子名称: ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Blenner, M.A, Dong, X, Springer, T.A.
登録日2013-08-16
公開日2014-01-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
4C2A
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Crystal Structure of High-Affinity von Willebrand Factor A1 domain with R1306Q and I1309V Mutations in Complex with High Affinity GPIb alpha
分子名称: ACETATE ION, CACODYLATE ION, CALCIUM ION, ...
著者Blenner, M.A, Dong, X, Springer, T.A.
登録日2013-08-16
公開日2014-01-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.081 Å)
主引用文献Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
4C2B
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Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation in Complex with High Affinity GPIb alpha
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ...
著者Blenner, M.A, Dong, X, Springer, T.A.
登録日2013-08-16
公開日2014-01-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
3EBM
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Crystal structure of human translationally controlled tumour associated protein (hTCTP) mutant E12V
分子名称: Translationally-controlled tumor protein
著者Yang, B, Dong, X, Zhong, C, Ding, J.
登録日2008-08-28
公開日2009-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of the acceleration of the GDP-GTP exchange of human ras homolog enriched in brain by human translationally controlled tumor protein.
J.Biol.Chem., 284, 2009
3PPV
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Crystal structure of an engineered VWF A2 domain (N1493C and C1670S)
分子名称: CALCIUM ION, SULFATE ION, von Willebrand factor
著者Zhou, M, Dong, X, Zhong, C, Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3PPX
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Crystal structure of the N1602A mutant of an engineered VWF A2 domain (N1493C and C1670S)
分子名称: SODIUM ION, von Willebrand factor
著者Zhou, M, Dong, X, Zhong, C, Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3PPW
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Crystal structure of the D1596A mutant of an engineered VWF A2 domain (N1493C and C1670S)
分子名称: SODIUM ION, von Willebrand factor
著者Zhou, M, Dong, X, Zhong, C, Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3PPY
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BU of 3ppy by Molmil
Crystal structure of the D1596A/N1602A double mutant of an engineered VWF A2 domain (N1493C and C1670S)
分子名称: SODIUM ION, von Willebrand factor
著者Zhou, M, Dong, X, Zhong, C, Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
8JAH
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Crystal structure of human CLEC12A C-type lectin domain
分子名称: C-type lectin domain family 12 member A, POTASSIUM ION, SULFATE ION
著者Lei, Q, Tang, H, Dong, X.
登録日2023-05-06
公開日2024-03-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Mechanistic insights into the C-type lectin receptor CLEC12A-mediated immune recognition of monosodium urate crystal.
J.Biol.Chem., 300, 2024
3JXE
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Crystal structure of Pyrococcus horikoshii tryptophanyl-tRNA synthetase in complex with TrpAMP
分子名称: SULFATE ION, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase
著者Zhou, M, Dong, X, Zhong, C, Shen, N, Yang, B, Ding, J.
登録日2009-09-19
公開日2009-11-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of P. horikoshii tryptophanyl-tRNA synthetase and structure-based phylogenetic analysis suggest an archaeal origin of tryptophanyl-tRNA synthetase
To be Published
3KT3
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Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase in complex with TrpAMP
分子名称: SULFATE ION, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase, ...
著者Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J.
登録日2009-11-24
公開日2010-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
Nucleic Acids Res., 38, 2010
3KT6
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Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase in complex with Trp
分子名称: SULFATE ION, TRYPTOPHAN, Tryptophanyl-tRNA synthetase, ...
著者Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J.
登録日2009-11-24
公開日2010-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
Nucleic Acids Res., 38, 2010
3KT0
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Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase
分子名称: (2S)-1-{[(2S)-3-(2-methoxyethoxy)-2-methylpropyl]oxy}propan-2-amine, Tryptophanyl-tRNA synthetase, cytoplasmic
著者Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J.
登録日2009-11-24
公開日2010-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
Nucleic Acids Res., 38, 2010
3KT8
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Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase in complex with L-tryptophanamide
分子名称: L-TRYPTOPHANAMIDE, SULFATE ION, Tryptophanyl-tRNA synthetase, ...
著者Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J.
登録日2009-11-24
公開日2010-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
Nucleic Acids Res., 38, 2010
6IZT
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Crystal structure of Haemophilus Influenzae BamA POTRA3-5
分子名称: Outer membrane protein assembly factor BamA
著者Ma, X, Wang, Q, Li, Y, Tan, P, Wu, H, Wang, P, Dong, X, Hong, L, Meng, G.
登録日2018-12-20
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献How BamA recruits OMP substratesviapoly-POTRAs domain.
Faseb J., 33, 2019
6IZS
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Crystal structure of Haemophilus influenzae BamA POTRA4
分子名称: Outer membrane protein assembly factor BamA
著者Ma, X, Wang, Q, Li, Y, Tan, P, Wu, H, Wang, P, Dong, X, Hong, L, Meng, G.
登録日2018-12-20
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献How BamA recruits OMP substratesviapoly-POTRAs domain.
Faseb J., 33, 2019
6J09
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Crystal structure of Haemophilus Influenzae BamA POTRA1-4
分子名称: Outer membrane protein assembly factor BamA
著者Ma, X, Wang, Q, Li, Y, Tan, P, Wu, H, Wang, P, Dong, X, Hong, L, Meng, G.
登録日2018-12-21
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献How BamA recruits OMP substratesviapoly-POTRAs domain.
Faseb J., 33, 2019
6DBS
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Fusion surface structure, function, and dynamics of gamete fusogen HAP2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hapless 2, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Feng, J, Dong, X, Springer, T.A.
登録日2018-05-03
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献Fusion surface structure, function, and dynamics of gamete fusogen HAP2.
Elife, 7, 2018

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