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PDB: 346 件
8JDN
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Crystal structure of H405A mLDHD in complex with D-2-hydroxyvaleric acid
分子名称: (2R)-2-oxidanylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDS
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Crystal structure of mLDHD in complex with Pyruvate
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, PYRUVIC ACID, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.636 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDB
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Crystal structure of H405A mLDHD in complex with D-2-hydroxyoctanoic acid
分子名称: (2R)-2-oxidanyloctanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-13
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDC
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Crystal structure of mLDHD in apo form
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-13
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDQ
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Crystal structure of H405A mLDHD in complex with D-2-hydroxyisocaproic acid
分子名称: (2R)-2-hydroxy-4-methylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDT
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BU of 8jdt by Molmil
Crystal structure of mLDHD in complex with 2-ketobutanoic acid
分子名称: 2-KETOBUTYRIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDV
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BU of 8jdv by Molmil
Crystal structure of mLDHD in complex with 2-ketohexanoic acid
分子名称: 2-Ketohexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDG
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Crystal structure of H405A mLDHD in complex with D-2-hydroxybutanoic acid
分子名称: (2R)-2-oxidanylbutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-14
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDR
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Crystal structure of H405A mLDHD in complex with D-2-hydroxy-3-methyl-valeric acid
分子名称: (2R,3S)-3-methyl-2-oxidanyl-pentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDU
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BU of 8jdu by Molmil
Crystal structure of mLDHD in complex with 2-ketovaleric acid
分子名称: 2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDY
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BU of 8jdy by Molmil
Crystal structure of mLDHD in complex with 2-ketoisocaproic acid
分子名称: 2-OXO-4-METHYLPENTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDD
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BU of 8jdd by Molmil
Crystal structure of H405A mLDHD in apo form
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-13
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDZ
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BU of 8jdz by Molmil
Crystal structure of mLDHD in complex with 2-keto-3-methylvaleric acid
分子名称: (3S)-3-methyl-2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDF
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BU of 8jdf by Molmil
Crystal structure of H405A mLDHD in complex with D-lactate
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-13
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDX
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BU of 8jdx by Molmil
Crystal structure of mLDHD in complex with 2-ketoisovaleric acid
分子名称: 3-METHYL-2-OXOBUTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDE
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BU of 8jde by Molmil
Crystal structure of mLDHD in complex with D-lactate
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-13
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.729 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDO
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BU of 8jdo by Molmil
Crystal structure of H405A mLDHD in complex with D-2-hydroxyhexanoic acid
分子名称: (2R)-2-hydroxyhexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDP
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BU of 8jdp by Molmil
Crystal structure of H405A mLDHD in complex with D-2-hydroxyisovaleric acid
分子名称: DEAMINOHYDROXYVALINE, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JKN
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BU of 8jkn by Molmil
T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAAA motif
分子名称: GAAA-Forward, GAAA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8J6K
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BU of 8j6k by Molmil
Crystal structure of pro-interleukin-18 and caspase-4 complex
分子名称: Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ...
著者Sun, Q, Hou, Y.J, Ding, J.
登録日2023-04-26
公開日2023-11-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome.
Nature, 624, 2023
1BQM
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BU of 1bqm by Molmil
HIV-1 RT/HBY 097
分子名称: (S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE, REVERSE TRANSCRIPTASE
著者Hsiou, Y, Das, K, Ding, J, Arnold, E.
登録日1998-08-17
公開日1999-01-06
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance.
J.Mol.Biol., 284, 1998
1BQN
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BU of 1bqn by Molmil
TYR 188 LEU HIV-1 RT/HBY 097
分子名称: (S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE, REVERSE TRANSCRIPTASE
著者Hsiou, Y, Das, K, Ding, J, Arnold, E.
登録日1998-08-17
公開日1999-01-06
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance.
J.Mol.Biol., 284, 1998
4M6W
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BU of 4m6w by Molmil
Crystal structure of the C-terminal segment of FANCM in complex with FAAP24
分子名称: Fanconi anemia group M protein, Fanconi anemia-associated protein of 24 kDa, SULFATE ION
著者Yang, H, Zhang, T, Tong, L, Ding, J.
登録日2013-08-11
公開日2013-10-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair.
Nucleic Acids Res., 41, 2013
8JKS
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BU of 8jks by Molmil
T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAGA motif
分子名称: GAGA-Forward, GAGA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8JKL
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BU of 8jkl by Molmil
IRF4 DNA-binding domain bound to an DNA containing GATA motif
分子名称: GATA-Forward, GATA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023

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件を2024-10-09に公開中

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