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PDB: 346 件

3MAS
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BU of 3mas by Molmil
Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate
分子名称: ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Yang, B, Peng, Y, Ding, J.
登録日2010-03-24
公開日2010-11-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H.
Cell Res., 20, 2010
4ZA1
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BU of 4za1 by Molmil
Crystal Structure of NosA Involved in Nosiheptide Biosynthesis
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, NosA
著者Liu, S, Guo, H, Zhang, T, Han, L, Yao, P, Zhang, Y, Rong, N, Yu, Y, Lan, W, Wang, C, Ding, J, Wang, R, Liu, W, Cao, C.
登録日2015-04-13
公開日2015-08-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides Biosynthesis
Sci Rep, 5, 2015
3MAR
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BU of 3mar by Molmil
Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP
分子名称: Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Yang, B, Peng, Y, Ding, J.
登録日2010-03-24
公開日2010-11-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H.
Cell Res., 20, 2010
5C3O
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BU of 5c3o by Molmil
Crystal structure of the C-terminal truncated Neurospora crassa T7H (NcT7HdeltaC) in apo form
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Thymine dioxygenase
著者Li, W, Zhang, T, Ding, J.
登録日2015-06-17
公開日2015-10-21
最終更新日2015-12-02
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
Nucleic Acids Res., 43, 2015
3DOE
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BU of 3doe by Molmil
Complex of ARL2 and BART, Crystal Form 1
分子名称: ADP-ribosylation factor-like protein 2, ADP-ribosylation factor-like protein 2-binding protein, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Zhang, T, Li, S, Ding, J.
登録日2008-07-04
公開日2009-03-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector
Structure, 17, 2009
4N3X
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BU of 4n3x by Molmil
Crystal structure of Rabex-5 CC domain
分子名称: Rab5 GDP/GTP exchange factor
著者Zhang, Z, Zhang, T, Ding, J.
登録日2013-10-08
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5
Elife, 3, 2014
4N3Z
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BU of 4n3z by Molmil
Crystal structure of Rabex-5delta and Rabaptin-5C21 complex
分子名称: PHOSPHATE ION, Rab GTPase-binding effector protein 1, Rab5 GDP/GTP exchange factor
著者Zhang, Z, Zhang, T, Ding, J.
登録日2013-10-08
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5
Elife, 3, 2014
1R0A
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BU of 1r0a by Molmil
Crystal structure of HIV-1 reverse transcriptase covalently tethered to DNA template-primer solved to 2.8 angstroms
分子名称: 5'-D(*A*TP*GP*CP*AP*TP*CP*GP*GP*CP*GP*CP*TP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*GP*GP*T)-3', 5'-D(*C*CP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*AP*GP*CP*GP*CP*CP*GP*(2DA))-3', GLYCEROL, ...
著者Tuske, S, Ding, J, Arnold, E.
登録日2003-09-19
公開日2004-08-03
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA.
J.Virol., 78, 2004
1T03
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BU of 1t03 by Molmil
HIV-1 reverse transcriptase crosslinked to tenofovir terminated template-primer (complex P)
分子名称: MAGNESIUM ION, POL polyprotein, Synthetic oligonucleotide primer, ...
著者Tuske, S, Sarafianos, S.G, Ding, J, Arnold, E.
登録日2004-04-07
公開日2004-05-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
Nat.Struct.Mol.Biol., 11, 2004
3PPV
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BU of 3ppv by Molmil
Crystal structure of an engineered VWF A2 domain (N1493C and C1670S)
分子名称: CALCIUM ION, SULFATE ION, von Willebrand factor
著者Zhou, M, Dong, X, Zhong, C, Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3PPX
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BU of 3ppx by Molmil
Crystal structure of the N1602A mutant of an engineered VWF A2 domain (N1493C and C1670S)
分子名称: SODIUM ION, von Willebrand factor
著者Zhou, M, Dong, X, Zhong, C, Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3QAH
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BU of 3qah by Molmil
Crystal structure of apo-form human MOF catalytic domain
分子名称: Probable histone acetyltransferase MYST1, ZINC ION
著者Sun, B, Tang, Q, Zhong, C, Ding, J.
登録日2011-01-11
公開日2011-07-06
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274
Cell Res., 21, 2011
3EO9
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BU of 3eo9 by Molmil
Crystal structure the Fab fragment of Efalizumab
分子名称: Efalizumab Fab fragment, heavy chain, light chain
著者Li, S, Ding, J.
登録日2008-09-26
公開日2009-04-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Proc.Natl.Acad.Sci.USA, 106, 2009
2MYJ
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BU of 2myj by Molmil
Solution structure of a bacterial chaperone
分子名称: Acid stress chaperone HdeB
著者Jin, C, Hu, Y, Ding, J.
登録日2015-01-27
公開日2016-01-06
実験手法SOLUTION NMR
主引用文献HdeB chaperone activity is coupled to its intrinsic dynamic properties.
Sci Rep, 5, 2015
3SP4
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BU of 3sp4 by Molmil
Crystal structure of aprataxin ortholog Hnt3 from Schizosaccharomyces pombe
分子名称: Aprataxin-like protein, SULFATE ION, ZINC ION
著者Gong, Y, Zhu, D, Ding, J, Dou, C, Ren, X, Jiang, T, Wang, D.
登録日2011-07-01
公開日2011-10-12
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
3PPY
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BU of 3ppy by Molmil
Crystal structure of the D1596A/N1602A double mutant of an engineered VWF A2 domain (N1493C and C1670S)
分子名称: SODIUM ION, von Willebrand factor
著者Zhou, M, Dong, X, Zhong, C, Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3PPW
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BU of 3ppw by Molmil
Crystal structure of the D1596A mutant of an engineered VWF A2 domain (N1493C and C1670S)
分子名称: SODIUM ION, von Willebrand factor
著者Zhou, M, Dong, X, Zhong, C, Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
5Y38
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BU of 5y38 by Molmil
Crystal structure of C7orf59-HBXIP complex
分子名称: Ragulator complex protein LAMTOR4, Ragulator complex protein LAMTOR5, SULFATE ION
著者Zhang, T, Ding, J.
登録日2017-07-28
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1
Nat Commun, 8, 2017
3SR9
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BU of 3sr9 by Molmil
Crystal structure of mouse PTPsigma
分子名称: Receptor-type tyrosine-protein phosphatase S
著者Wang, J, Hou, L, Li, J, Ding, J.
登録日2011-07-07
公開日2012-05-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into the homology and differences between mouse protein tyrosine phosphatase-sigma and human protein tyrosine phosphatase-sigma
Acta Biochim.Biophys.Sin., 43, 2011
4M6W
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BU of 4m6w by Molmil
Crystal structure of the C-terminal segment of FANCM in complex with FAAP24
分子名称: Fanconi anemia group M protein, Fanconi anemia-associated protein of 24 kDa, SULFATE ION
著者Yang, H, Zhang, T, Tong, L, Ding, J.
登録日2013-08-11
公開日2013-10-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair.
Nucleic Acids Res., 41, 2013
7F00
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BU of 7f00 by Molmil
Crystal structure of SPD_0310
分子名称: SULFATE ION, UPF0371 protein SPRM200_0309
著者Cao, K, Zhang, T, Li, N, Yang, X, Ding, J, He, Q, Sun, X.
登録日2021-06-03
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification and Tetramer Structure of Hemin-Binding Protein SPD_0310 Linked to Iron Homeostasis and Virulence of Streptococcus pneumoniae.
Msystems, 7, 2022

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