1ELF
 
 | | NATURE OF THE INACTIVATION OF ELASTASE BY N-PEPTIDYL-O-AROYL HYDROXYLAMINE AS A FUNCTION OF PH | | 分子名称: | (TERT-BUTYLOXYCARBONYL)-ALANYL-AMINO ETHYL-FORMAMIDE, CALCIUM ION, PORCINE PANCREATIC ELASTASE, ... | | 著者 | Ding, X, Rasmussen, B, Demuth, H.-U, Ringe, D, Steinmetz, A.C.U. | | 登録日 | 1995-03-13 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Nature of the inactivation of elastase by N-peptidyl-O-aroyl hydroxylamine as a function of pH.
Biochemistry, 34, 1995
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1ELG
 | | NATURE OF THE INACTIVATION OF ELASTASE BY N-PEPTIDYL-O-AROYL HYDROXYLAMINE AS A FUNCTION OF PH | | 分子名称: | (TERT-BUTYLOXYCARBONYL)-ALANYL-ALANYL-AMINE, CALCIUM ION, PORCINE PANCREATIC ELASTASE | | 著者 | Ding, X, Rasmussen, B, Demuth, H.-U, Ringe, D, Steinmetz, A.C.U. | | 登録日 | 1995-03-13 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Nature of the inactivation of elastase by N-peptidyl-O-aroyl hydroxylamine as a function of pH.
Biochemistry, 34, 1995
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1ESA
 | | DIRECT STRUCTURE OBSERVATION OF AN ACYL-ENZYME INTERMEDIATE IN THE HYDROLYSIS OF AN ESTER SUBSTRATE BY ELASTASE | | 分子名称: | CALCIUM ION, PORCINE PANCREATIC ELASTASE, SULFATE ION | | 著者 | Ding, X, Rasmussen, B, Petsko, G.A, Ringe, D. | | 登録日 | 1994-02-04 | | 公開日 | 1994-04-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase.
Biochemistry, 33, 1994
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1ESB
 | | DIRECT STRUCTURE OBSERVATION OF AN ACYL-ENZYME INTERMEDIATE IN THE HYDROLYSIS OF AN ESTER SUBSTRATE BY ELASTASE | | 分子名称: | CALCIUM ION, N-[(BENZYLOXY)CARBONYL]-L-ALANINE, PORCINE PANCREATIC ELASTASE, ... | | 著者 | Ding, X, Rasmussen, B, Petsko, G.A, Ringe, D. | | 登録日 | 1994-02-04 | | 公開日 | 1994-04-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase.
Biochemistry, 33, 1994
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8XAM
 | | Co-crystal structure of compound 7 in complex with MAT2A | | 分子名称: | 2-[3-[7-chloranyl-4-(dimethylamino)-2-oxidanylidene-quinazolin-1-yl]phenoxy]-~{N}-[3-[7-chloranyl-4-(dimethylamino)-2-oxidanylidene-quinazolin-1-yl]phenyl]ethanamide, S-ADENOSYLMETHIONINE, S-adenosylmethionine synthase isoform type-2 | | 著者 | Gao, F, Ding, X. | | 登録日 | 2023-12-04 | | 公開日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Discovery of novel MAT2A inhibitors by an allosteric site-compatible fragment growing approach.
Bioorg.Med.Chem., 100, 2024
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8WJY
 | | PKMYT1_Cocrystal_Cpd 4 | | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, ... | | 著者 | Wang, Y, Wang, C, Liu, T, Qi, H, Chen, S, Cai, X, Zhang, M, Aliper, A, Ren, F, Ding, X, Zhavoronkov, A. | | 登録日 | 2023-09-26 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Discovery of Tetrahydropyrazolopyrazine Derivatives as Potent and Selective MYT1 Inhibitors for the Treatment of Cancer.
J.Med.Chem., 67, 2024
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8J1K
 | | co-crystal structure of non-carboxylic acid inhibitor with PHD2 | | 分子名称: | Egl nine homolog 1, MANGANESE (II) ION, N-[(6-cyanopyridin-3-yl)methyl]-5-oxidanyl-2-[(3R)-3-oxidanylpyrrolidin-1-yl]-1,7-naphthyridine-6-carboxamide | | 著者 | Xu, J, Fu, Y, Ding, X, Meng, Q, Wang, L, Zhang, M, Ding, X, Ren, F, Zhavoronkov, A. | | 登録日 | 2023-04-13 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.451 Å) | | 主引用文献 | co-crystal structure of non-carboxylic acid inhibitor with PHD2
To Be Published
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1DDN
 | | DIPHTHERIA TOX REPRESSOR (C102D MUTANT)/TOX DNA OPERATOR COMPLEX | | 分子名称: | 33 BASE DNA CONTAINING TOXIN OPERATOR, DIPHTHERIA TOX REPRESSOR, NICKEL (II) ION | | 著者 | White, A, Ding, X, Vanderspek, J.C, Murphy, J.R, Ringe, D. | | 登録日 | 1998-06-23 | | 公開日 | 1998-10-14 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex.
Nature, 394, 1998
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1ELA
 | | Analogous inhibitors of elastase do not always bind analogously | | 分子名称: | 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-prolinamide, ACETIC ACID, CALCIUM ION, ... | | 著者 | Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D. | | 登録日 | 1993-12-07 | | 公開日 | 1994-04-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Analogous inhibitors of elastase do not always bind analogously.
Nat.Struct.Biol., 1, 1994
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1ELB
 | | Analogous inhibitors of elastase do not always bind analogously | | 分子名称: | 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-leucinamide, CALCIUM ION, ELASTASE, ... | | 著者 | Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D. | | 登録日 | 1993-12-07 | | 公開日 | 1994-06-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Analogous inhibitors of elastase do not always bind analogously.
Nat.Struct.Biol., 1, 1994
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1ELC
 | | Analogous inhibitors of elastase do not always bind analogously | | 分子名称: | 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-phenylalaninamide, CALCIUM ION, ELASTASE | | 著者 | Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D. | | 登録日 | 1993-12-07 | | 公開日 | 1994-04-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Analogous inhibitors of elastase do not always bind analogously.
Nat.Struct.Biol., 1, 1994
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4NFT
 | | Crystal structure of human lnkH2B-h2A.Z-Anp32e | | 分子名称: | Acidic leucine-rich nuclear phosphoprotein 32 family member E, Histone H2B type 2-E, Histone H2A.Z | | 著者 | Shan, S, Pan, L, Mao, Z, Wang, W, Sun, J, Dong, Q, Liang, X, Ding, X, Chen, S, Dai, L, Zhang, Z, Zhu, B, Zhou, Z. | | 登録日 | 2013-11-01 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z
Cell Res., 24, 2014
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4MZH
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4MZF
 | | Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2a) peptide | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Peptide from Histone H3.2, ... | | 著者 | Su, X, Ding, X, Li, H. | | 登録日 | 2013-09-30 | | 公開日 | 2014-03-26 | | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | | 主引用文献 | Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1
Genes Dev., 28, 2014
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4MZG
 | | Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... | | 著者 | Su, X, Ding, X, Li, H. | | 登録日 | 2013-09-30 | | 公開日 | 2014-03-26 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1
Genes Dev., 28, 2014
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2TDX
 | | DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL | | 分子名称: | DIPHTHERIA TOX REPRESSOR, NICKEL (II) ION | | 著者 | White, A, Ding, X, Zheng, H, Schiering, N, Ringe, D, Murphy, J.R. | | 登録日 | 1998-06-22 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex.
Nature, 394, 1998
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7UD4
 | | Cryo-EM structure of AAV-PHP.eB | | 分子名称: | Capsid protein VP1 | | 著者 | Jang, S, Shen, H.K, Ding, X, Miles, T.F, Gradinaru, V. | | 登録日 | 2022-03-18 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.24 Å) | | 主引用文献 | Structural basis of receptor usage by the engineered capsid AAV-PHP.eB.
Mol Ther Methods Clin Dev, 26, 2022
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