7UD4

Cryo-EM structure of AAV-PHP.eB

This is a non-PDB format compatible entry.

Summary for 7UD4

• Entry DOI: 10.2210/pdb7ud4/pdb
• EMDB information: 26417 26453
• Descriptor: Capsid protein VP1 (1 entity in total)
• Functional Keywords: gene therapy, aav, capsid, blood-brain barrier, directed evolution, virus
• Biological source: Adeno-associated virus
• Total number of polymer chains: 1
• Total formula weight: 82188.61

Authors

Jang, S.,Shen, H.K.,Ding, X.,Miles, T.F.,Gradinaru, V. (deposition date: 2022-03-18, release date: 2022-09-21, Last modification date: 2024-06-12)

• Primary citation: Jang, S.,Shen, H.K.,Ding, X.,Miles, T.F.,Gradinaru, V.; Structural basis of receptor usage by the engineered capsid AAV-PHP.eB.; Mol Ther Methods Clin Dev, 26:343-354, 2022; PubMed: 36034770; DOI: 10.1016/j.omtm.2022.07.011

Experimental method

ELECTRON MICROSCOPY (2.24 Å)