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PDB: 8 件

2OGM
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The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative SB-571519
分子名称: (2S,3AR,4R,5S,6S,8R,9R,9AR,10R)-2,5-DIHYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROP[1]ENOCYCLOPENTA[8]ANNULEN-8-YL [(6-AMINOPYRIDAZIN-3-YL)CARBONYL]CARBAMATE, 23S ribosomal RNA, 50S ribosomal protein L3
著者Davidovich, C, Bashan, A, Auerbach-Nevo, T, Yonath, A.
登録日2007-01-07
公開日2007-05-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OGN
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BU of 2ogn by Molmil
The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative SB-280080
分子名称: (3AS,4R,5S,6S,8R,9R,9AR,10R)-5-HYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROPANOCYCLOPENTA[8]ANNULEN-8-YL (PIPERIDIN-4-YLTHIO)ACETATE, 23S ribosomal RNA, 50S ribosomal protein L3
著者Davidovich, C, Bashan, A, Auerbach-Nevo, T, Yonath, A.
登録日2007-01-07
公開日2007-05-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.56 Å)
主引用文献Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OGO
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BU of 2ogo by Molmil
The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative retapamulin (SB-275833)
分子名称: 23S ribosomal RNA, 50S ribosomal protein L3, Retapamulin
著者Davidovich, C, Bashan, A, Auerbach-Nevo, T, Yonath, A.
登録日2007-01-07
公開日2007-05-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.66 Å)
主引用文献Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
8EQV
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BU of 8eqv by Molmil
Cryo-EM structure of PRC2 in complex with the long isoform of AEBP2
分子名称: Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, ...
著者Boudes, M, Zhang, Q, Flanigan, S.F, Davidovich, C.
登録日2022-10-09
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献To be updated
To Be Published
6V3X
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BU of 6v3x by Molmil
Crystal structure of EED in complex with PALI1-K1241me3 peptide
分子名称: PALI1 peptide, Polycomb protein EED
著者Zhang, Q, Davidovich, C.
登録日2019-11-26
公開日2021-05-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.
Nat Commun, 12, 2021
6V3Y
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BU of 6v3y by Molmil
Crystal structure of EED in complex with PALI1-K1219me3 peptide
分子名称: PALI1 peptide, Polycomb protein EED
著者Zhang, Q, Davidovich, C.
登録日2019-11-26
公開日2021-05-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.
Nat Commun, 12, 2021
3JQ4
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BU of 3jq4 by Molmil
The structure of the complex of the large ribosomal subunit from D. Radiodurans with the antibiotic lankacidin
分子名称: 23S ribosomal RNA, 5S ribosomal RNA, N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7,13-dihydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetraen-2-yl]-2-oxopropanamide
著者Auerbach-Nevo, T, Mermershtain, I, Davidovich, C, Bashan, A, Rozenberg, H, Yonath, A.
登録日2009-09-06
公開日2010-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics
Proc.Natl.Acad.Sci.USA, 107, 2010
3FWO
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BU of 3fwo by Molmil
The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin
分子名称: (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA
著者Auerbach, T, Mermershtain, I, Bashan, A, Davidovich, C, Rozenberg, H, Sherman, D.H, Yonath, A.
登録日2009-01-19
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.71 Å)
主引用文献Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin
Biotechnologia, 1, 2009

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件を2024-10-09に公開中

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