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PDB: 22 件

5W5H
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BU of 5w5h by Molmil
Human IFIT1 dimer with m7Gppp-AAAA
分子名称: Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3')
著者Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B.
登録日2017-06-15
公開日2017-07-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding
To Be Published
7ZYX
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BU of 7zyx by Molmil
Dimeric i-motif from 2'Farabinocytidine-modified TC5
分子名称: DNA (5'-D(*TP*(CFL)P*(CFL)P*(CFL)P*(CFL)P*(CFL))-3')
著者Garavis, M, El Khoury, R, Damha, M.J, Gonzalez, C.
登録日2022-05-25
公開日2023-03-01
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献i-Motif folding intermediates with zero-nucleotide loops are trapped by 2'-fluoroarabinocytidine via F···H and O···H hydrogen bonds.
Commun Chem, 6, 2023
4PEI
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BU of 4pei by Molmil
Dbr1 in complex with synthetic branched RNA analog
分子名称: GLYCEROL, NICKEL (II) ION, RNA (5'-R(*(G46)P*U)-3'), ...
著者Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J.
登録日2014-04-23
公開日2014-08-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1.
Nucleic Acids Res., 42, 2014
4PEG
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BU of 4peg by Molmil
Dbr1 in complex with guanosine-5'-monophosphate
分子名称: GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ...
著者Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J.
登録日2014-04-23
公開日2014-08-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1.
Nucleic Acids Res., 42, 2014
4PEF
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BU of 4pef by Molmil
Dbr1 in complex with sulfate
分子名称: GLYCEROL, MANGANESE (II) ION, RNA lariat debranching enzyme, ...
著者Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J.
登録日2014-04-23
公開日2014-08-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1.
Nucleic Acids Res., 42, 2014
5MJX
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BU of 5mjx by Molmil
2'F-ANA/DNA Chimeric TBA Quadruplex structure
分子名称: DNA (5'-D(*GP*GP*(FT)P*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3')
著者Lietard, J, Abou Assi, H, Gomez-Pinto, I, Gonzalez, C, Somoza, M.M, Damha, M.J.
登録日2016-12-02
公開日2017-02-01
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Mapping the affinity landscape of Thrombin-binding aptamers on 2 F-ANA/DNA chimeric G-Quadruplex microarrays.
Nucleic Acids Res., 45, 2017
4PEH
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BU of 4peh by Molmil
Dbr1 in complex with synthetic linear RNA
分子名称: GLYCEROL, MANGANESE (II) ION, RNA (5'-R(*CP*UP*AP*(A2P)P*AP*CP*AP*A)-3'), ...
著者Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J.
登録日2014-04-23
公開日2014-08-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1.
Nucleic Acids Res., 42, 2014
8QE4
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BU of 8qe4 by Molmil
Formation of left-handed helices by C2'-fluorinated nucleic acids under physiological salt conditions
分子名称: DNA (5'-D(*CP*(FRG)P*CP*(FRG)P*CP*(FRG))-3')
著者El-Khoury, R, Cabrero, C, Movilla, S, Friedland, D, Thorpe, J.D, Roman, M, Orozco, M, Gonzalez, C, Damha, M.
登録日2023-08-30
公開日2024-06-26
実験手法SOLUTION NMR
主引用文献Formation of left-handed helices by C2'-fluorinated nucleic acids under physiological salt conditions.
Nucleic Acids Res., 2024
8QOR
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BU of 8qor by Molmil
Formation of left-handed helices by C2'-fluorinated nucleic acids under physiological salt conditions
分子名称: DNA (5'-D(*(CFL)P*(FRG)P*(CFL)P*(FRG)P*(CFL)P*(FRG))-3')
著者El-Khoury, R, Cabrero, C, Movilla, S, Friedland, D, Thorpe, J.D, Roman, M, Orozco, M, Gonzalez, C, Damha, M.
登録日2023-09-29
公開日2024-06-26
実験手法SOLUTION NMR
主引用文献Formation of left-handed helices by C2'-fluorinated nucleic acids under physiological salt conditions.
Nucleic Acids Res., 2024
2LSC
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BU of 2lsc by Molmil
Solution structure of 2'F-ANA and ANA self-complementary duplex
分子名称: DNA (5'-D(*(CFL)P*(GFL)P*(CFL)P*(GFL)P*(A5O)P*(A5O)P*(UAR)P*(UAR)P*(CFL)P*(GFL)P*(CFL)P*(GFL))-3')
著者Martin-Pintado, N, Yahyaee, M, Campos, R, Noronha, A, Wilds, C, Damha, M, Gonzalez, C.
登録日2012-04-26
公開日2012-07-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversion.
Nucleic Acids Res., 40, 2012
8QDU
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BU of 8qdu by Molmil
Formation of left-handed helices by C2'-fluorinated nucleic acids under physiological salt conditions
分子名称: DNA (5'-D(*(FC)P*GP*(FC)P*GP*(FC)P*G)-3')
著者El-Khoury, R, Cabrero, C, Movilla, S, Thorpe, J.D, Roman, M, Orozco, M, Gonzalez, C, Damha, M.J.
登録日2023-08-30
公開日2024-06-26
実験手法SOLUTION NMR
主引用文献Formation of left-handed helices by C2'-fluorinated nucleic acids under physiological salt conditions.
Nucleic Acids Res., 2024
1ME1
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BU of 1me1 by Molmil
Chimeric hairpin with 2',5'-linked RNA loop and RNA stem
分子名称: 5'-R(*GP*GP*AP*CP*(U25)P*(U25)P*(C25)P*(5GP)P*GP*UP*CP*C)-3'
著者Denisov, A.Y, Hannoush, R.N, Gehring, K, Damha, M.J.
登録日2002-08-07
公開日2003-08-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A Novel RNA Motif Based on the Structure of Unusually Stable 2',5'-Linked r(UUCG) Loops
J.AM.CHEM.SOC., 125, 2003
1ME0
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BU of 1me0 by Molmil
Chimeric hairpin with 2',5'-linked RNA loop and DNA stem
分子名称: DNA/RNA (5'-D(*GP*GP*AP*C)-R(P*(U25)P*(U25)P*(C25)P*(5GP))-D(P*GP*TP*CP*C)-3')
著者Denisov, A.Y, Hannoush, R.N, Gehring, K, Damha, M.J.
登録日2002-08-07
公開日2003-08-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A Novel RNA Motif Based on the Structure of Unusually Stable 2',5'-Linked r(UUCG) Loops
J.AM.CHEM.SOC., 125, 2003
2M8A
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BU of 2m8a by Molmil
2'F-ANA/2'F-RNA alternated sequences
分子名称: 2'F-RNA/2'F-ANA chimeric duplex
著者Martin-Pintado, N, Deleavey, G, Portella, G, Campos, R, Orozco, M, Damha, M, Gonzalez, C.
登録日2013-05-14
公開日2013-11-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Backbone FCHO Hydrogen Bonds in 2'F-Substituted Nucleic Acids.
Angew.Chem.Int.Ed.Engl., 52, 2013
2M84
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BU of 2m84 by Molmil
Structure of 2'F-RNA/2'F-ANA chimeric duplex
分子名称: 2'F-RNA/2'F-ANA CHIMERIC DUPLEX
著者Martin-Pintado, N, Deleavey, G, Portella, G, Campos, R, Orozco, M, Damha, M, Gonzalez, C.
登録日2013-05-07
公開日2013-11-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Backbone FCHO Hydrogen Bonds in 2'F-Substituted Nucleic Acids.
Angew.Chem.Int.Ed.Engl., 52, 2013
2M1G
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BU of 2m1g by Molmil
Parallel human telomeric quadruplex containing 2'F-ANA substitutions
分子名称: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(GFL)P*GP*GP*T)-3'
著者Martin-Pintado, N, Yahyaee-Anzahaee, M, Deleavey, G.F, Portella, G, Orozco, M, Damha, M.J, Gonzalez, C.
登録日2012-11-27
公開日2013-05-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Dramatic effect of furanose c2' substitution on structure and stability: directing the folding of the human telomeric quadruplex with a single fluorine atom.
J.Am.Chem.Soc., 135, 2013
5UDJ
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BU of 5udj by Molmil
IFIT1 monomeric mutant (L457E/L464E) with Gppp-AAAA
分子名称: CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(G3A))-R(P*AP*AP*A)-3'), ...
著者Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B.
登録日2016-12-27
公開日2017-03-01
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UDI
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BU of 5udi by Molmil
IFIT1 monomeric mutant (L457E/L464E) with m7Gppp-AAAA (syn and anti conformations of cap)
分子名称: CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ...
著者Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B.
登録日2016-12-27
公開日2017-03-01
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UDL
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BU of 5udl by Molmil
IFIT1 N216A monomeric mutant (L457E/L464E) with m7Gppp-AAAA (anti conformation of cap)
分子名称: CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ...
著者Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B.
登録日2016-12-27
公開日2017-03-01
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UDK
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BU of 5udk by Molmil
IFIT1 monomeric mutant (L457E/L464E) with PPP-AAAA
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B.
登録日2016-12-27
公開日2017-03-01
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W5I
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BU of 5w5i by Molmil
Human IFIT1 dimer with PPP-AAAA
分子名称: Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(ATP))-R(P*AP*AP*A)-3')
著者Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B.
登録日2017-06-15
公開日2017-06-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding
To Be Published
2N89
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BU of 2n89 by Molmil
Tetrameric i-motif structure of dT-dC-dC-CFL-CFL-dC at acidic pH
分子名称: DNA (5'-D(*TP*CP*CP*(CFL)P*(CFL)P*C)-3')
著者Abou-Assi, H, Harkness, R.W, Martin-Pintado, N, Wilds, C.J, Campos-Olivas, R, Mittermaier, A.K, Gonzalez, C, Damha, M.J.
登録日2015-10-09
公開日2016-08-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Stabilization of i-motif structures by 2'-beta-fluorination of DNA.
Nucleic Acids Res., 44, 2016

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件を2024-07-17に公開中

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